hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00960
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HSP90B1 | Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog) | UniProt NCBI |
| GANAB | Neutral alpha-glucosidase AB (EC 3.2.1.207) (Alpha-glucosidase 2) (Glucosidase II subunit alpha) | UniProt NCBI |
| LONP2 | Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon) | UniProt NCBI |
| OS9 | Protein OS-9 (Amplified in osteosarcoma 9) | UniProt NCBI |
| CBX3 | Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6859 | 0.000522504524138 | 0.4 | OS9 HSP90B1 | HRD1 complex |
| KEGG:04141 | 0.000538800909475 | 0.6 | GANAB OS9 HSP90B1 | Protein processing in endoplasmic reticulum |
| REAC:R-HSA-901042 | 0.00437263170532 | 0.4 | OS9 GANAB | Calnexin/calreticulin cycle |
| REAC:R-HSA-532668 | 0.00799559968784 | 0.4 | OS9 GANAB | N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| OS9 | HSP90B1 | 0.549 | 0.643 | hein_WMM bioplex (OS9) bioplex_WMM hein (HSP90B1) gupta_WMM |
| OS9 | LONP2 | 0.053 | 0.301 | bioplex (OS9) bioplex_WMM |
| HSP90B1 | GANAB | 0.044 | 0.28 | hein_WMM bioplex (GANAB) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| CBX3 | HSP90B1 | 0.042 | 0.27 | bioplex_WMM youn_WMM gupta_WMM fraction |
| LONP2 | GANAB | 0.007 | 0.001 | bioplex_WMM WMM_only |
| LONP2 | CBX3 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| OS9 | CBX3 | 0.007 | 0.004 | gupta_WMM WMM_only |
| LONP2 | HSP90B1 | 0.006 | 0.003 | bioplex_WMM WMM_only |
| OS9 | GANAB | 0.0 | 0.009 | bioplex (OS9) bioplex_WMM gupta_WMM boldt_WMM |
| CBX3 | GANAB | 0.0 | 0.004 | bioplex (GANAB) boldt youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_00960 has an average edge precision of 0.152 which is ranked 6692 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HSP90B1 | HuMAP2_00960 HuMAP2_01492 HuMAP2_01924 HuMAP2_03097 HuMAP2_03795 |
| GANAB | HuMAP2_00960 |
| LONP2 | HuMAP2_00960 HuMAP2_01630 HuMAP2_02623 HuMAP2_06933 |
| OS9 | HuMAP2_00960 HuMAP2_01924 HuMAP2_01997 HuMAP2_03097 HuMAP2_06289 HuMAP2_06933 |
| CBX3 | HuMAP2_00960 HuMAP2_02094 HuMAP2_03097 HuMAP2_04364 |