hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00961
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RGPD5 | RANBP2-like and GRIP domain-containing protein 5/6 (Ran-binding protein 2-like 1/2) (RanBP2-like 1/2) (RanBP2L1) (RanBP2L2) (Sperm membrane protein BS-63) | UniProt NCBI |
| SUMO1 | Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1) | UniProt NCBI |
| RGPD8 | RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) | UniProt NCBI |
| RGPD3 | RanBP2-like and GRIP domain-containing protein 3 | UniProt NCBI |
| RCC1 | Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) | UniProt NCBI |
| RANBP1 | Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0008536 | 1.54127830699e-06 | 0.8 | RCC1 RGPD3 RGPD8 RANBP1 | Ran GTPase binding |
| GO:0005643 | 0.000164422098058 | 0.8 | SUMO1 RGPD3 RGPD8 RANBP1 | nuclear pore |
| GO:0005635 | 0.000201815974304 | 1.0 | RCC1 RGPD3 SUMO1 RGPD8 RANBP1 | nuclear envelope |
| REAC:R-HSA-165054 | 0.00625202329777 | 0.4 | RCC1 RANBP1 | Rev-mediated nuclear export of HIV RNA |
| REAC:R-HSA-177243 | 0.00709716303977 | 0.4 | RCC1 RANBP1 | Interactions of Rev with host cellular proteins |
| CORUM:7567 | 0.0249780992026 | 0.2 | SUMO1 | SUMO1-SYT7 complex |
| GO:0031967 | 0.0253087624128 | 1.0 | RCC1 RGPD3 SUMO1 RGPD8 RANBP1 | organelle envelope |
| GO:0031975 | 0.0253087624128 | 1.0 | RCC1 RGPD3 SUMO1 RGPD8 RANBP1 | envelope |
| GO:0017016 | 0.0351481133305 | 0.8 | RCC1 RGPD3 RGPD8 RANBP1 | Ras GTPase binding |
| GO:0031267 | 0.0441192366731 | 0.8 | RCC1 RGPD3 RGPD8 RANBP1 | small GTPase binding |
| CORUM:680 | 0.0499494897235 | 0.2 | RANBP1 | RANBMP-CD39 complex |
| CORUM:1056 | 0.0499494897235 | 0.2 | SUMO1 | ZNF198-SUMO1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RCC1 | RGPD8 | 1.0 | 0.949 | hein_WMM bioplex (RCC1) bioplex_WMM youn_WMM hein (RCC1) gupta_WMM |
| RCC1 | RANBP1 | 1.0 | 0.949 | hein_WMM bioplex (RCC1) bioplex_WMM youn_WMM hein (RANBP1,RCC1) gupta_WMM treiber_WMM |
| RCC1 | RGPD3 | 0.884 | 0.816 | bioplex (RCC1) bioplex_WMM gupta_WMM |
| RCC1 | RGPD5 | 0.772 | 0.751 | bioplex (RCC1) bioplex_WMM |
| RCC1 | SUMO1 | 0.756 | 0.747 | hein_WMM bioplex (RCC1) bioplex_WMM youn_WMM hein (RCC1) gupta_WMM |
| RGPD8 | RGPD5 | 0.039 | 0.266 | bioplex_WMM WMM_only |
| SUMO1 | RGPD8 | 0.017 | 0.175 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RGPD8 | RGPD3 | 0.015 | 0.138 | bioplex_WMM gupta_WMM WMM_only |
| RGPD3 | RGPD5 | 0.013 | 0.154 | bioplex_WMM WMM_only |
| SUMO1 | RGPD5 | 0.01 | 0.131 | bioplex_WMM WMM_only |
| RGPD8 | RANBP1 | 0.009 | 0.096 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RANBP1 | RGPD5 | 0.008 | 0.044 | bioplex_WMM WMM_only |
| RANBP1 | RGPD3 | 0.008 | 0.032 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SUMO1 | RGPD3 | 0.008 | 0.028 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SUMO1 | RANBP1 | 0.003 | 0.011 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_00961 has an average edge precision of 0.352 which is ranked 3904 out of all 6965 complexes.
Related Complexes