hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00983
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| JADE2 | E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15) | UniProt NCBI |
| ING4 | Inhibitor of growth protein 4 (p29ING4) | UniProt NCBI |
| ING5 | Inhibitor of growth protein 5 (p28ING5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2847 | 2.01342304124e-05 | 0.666666666667 | JADE2 ING4 | ING4 complex (ING4, JADE2, KAT7, MEAF6) |
| CORUM:7254 | 2.01342304124e-05 | 0.666666666667 | JADE2 ING5 | ING5 complex (ING5, JADE2, KAT7, MEAF6) |
| REAC:R-HSA-3214847 | 0.000210042684884 | 1.0 | JADE2 ING4 ING5 | HATs acetylate histones |
| REAC:R-HSA-3247509 | 0.00144234915262 | 1.0 | JADE2 ING4 ING5 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.00144234915262 | 1.0 | JADE2 ING4 ING5 | Chromatin organization |
| GO:0043966 | 0.00178004409005 | 1.0 | JADE2 ING4 ING5 | histone H3 acetylation |
| GO:0000123 | 0.00690911398953 | 1.0 | JADE2 ING4 ING5 | histone acetyltransferase complex |
| GO:0031248 | 0.00996606725847 | 1.0 | JADE2 ING4 ING5 | protein acetyltransferase complex |
| GO:1902493 | 0.00996606725847 | 1.0 | JADE2 ING4 ING5 | acetyltransferase complex |
| GO:0016573 | 0.0180261250619 | 1.0 | JADE2 ING4 ING5 | histone acetylation |
| GO:0018393 | 0.0190659069388 | 1.0 | JADE2 ING4 ING5 | internal peptidyl-lysine acetylation |
| GO:0043983 | 0.020283420769 | 0.666666666667 | JADE2 ING4 | histone H4-K12 acetylation |
| GO:0006475 | 0.0218385980648 | 1.0 | JADE2 ING4 ING5 | internal protein amino acid acetylation |
| GO:0018394 | 0.022423560513 | 1.0 | JADE2 ING4 ING5 | peptidyl-lysine acetylation |
| GO:0006473 | 0.047104416733 | 1.0 | JADE2 ING4 ING5 | protein acetylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| JADE2 | ING4 | 1.0 | 0.949 | hein_WMM bioplex (JADE2) bioplex_WMM hein (ING4) |
| JADE2 | ING5 | 0.994 | 0.919 | bioplex (JADE2) bioplex_WMM |
| ING5 | ING4 | 0.011 | 0.137 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00983 has an average edge precision of 0.668 which is ranked 1527 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| JADE2 | HuMAP2_00983 HuMAP2_02043 HuMAP2_06383 |
| ING4 | HuMAP2_00983 HuMAP2_02043 HuMAP2_06383 |
| ING5 | HuMAP2_00983 HuMAP2_02043 HuMAP2_06383 |