hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00989
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ASAH1 | Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta] | UniProt NCBI |
| CCDC32 | Coiled-coil domain-containing protein 32 | UniProt NCBI |
| AAGAB | Alpha- and gamma-adaptin-binding protein p34 | UniProt NCBI |
| AP1S3 | AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit of AP-1 clathrin) (Sigma-adaptin 1C) (Sigma1C-adaptin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04142 | 0.0136880283161 | 0.5 | ASAH1 AP1S3 | Lysosome |
| CORUM:7098 | 0.0499140284799 | 0.25 | ASAH1 | ASAH1-NR5A1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ASAH1 | AAGAB | 0.202 | 0.452 | bioplex (AAGAB) bioplex_WMM |
| CCDC32 | AAGAB | 0.064 | 0.349 | bioplex (AAGAB) bioplex_WMM |
| AAGAB | AP1S3 | 0.043 | 0.269 | bioplex (AAGAB) bioplex_WMM |
| CCDC32 | AP1S3 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| ASAH1 | CCDC32 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| ASAH1 | AP1S3 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00989 has an average edge precision of 0.192 which is ranked 6287 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ASAH1 | HuMAP2_00834 HuMAP2_00989 HuMAP2_01734 HuMAP2_03338 HuMAP2_04980 HuMAP2_06143 |
| CCDC32 | HuMAP2_00989 HuMAP2_02111 HuMAP2_02595 HuMAP2_03002 HuMAP2_04081 HuMAP2_06613 HuMAP2_06626 |
| AAGAB | HuMAP2_00989 HuMAP2_03338 HuMAP2_06143 |
| AP1S3 | HuMAP2_00989 HuMAP2_02368 HuMAP2_03338 HuMAP2_03989 HuMAP2_06613 |