hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01019
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DNMT1 | DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT) | UniProt NCBI |
| UGT3A2 | UDP-glucuronosyltransferase 3A2 (UDPGT 3A2) (EC 2.4.1.17) | UniProt NCBI |
| ACAT1 | Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2) | UniProt NCBI |
| CRIPT | Cysteine-rich PDZ-binding protein (Cysteine-rich interactor of PDZ three) (Cysteine-rich interactor of PDZ3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001262 | 0.00986303631958 | 0.5 | ACAT1 DNMT1 | Excessive daytime somnolence |
| HP:0000741 | 0.0195010181256 | 0.5 | ACAT1 DNMT1 | Apathy |
| HP:0000745 | 0.023433582519 | 0.5 | ACAT1 DNMT1 | Diminished motivation |
| WP:WP311 | 0.0416857670091 | 0.25 | ACAT1 | Synthesis and Degradation of Ketone Bodies |
| CORUM:862 | 0.0499140284799 | 0.25 | DNMT1 | DNMT1-EHMT2 complex |
| CORUM:6336 | 0.0499140284799 | 0.25 | DNMT1 | CTNNB1-DNMT1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UGT3A2 | ACAT1 | 0.102 | 0.365 | fraction |
| CRIPT | ACAT1 | 0.036 | 0.265 | fraction |
| ACAT1 | DNMT1 | 0.034 | 0.261 | bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| CRIPT | DNMT1 | 0.0 | 0.0 | fraction |
Images
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Complex HuMAP2_01019 has an average edge precision of 0.223 which is ranked 5814 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DNMT1 | HuMAP2_01019 HuMAP2_02434 HuMAP2_06314 HuMAP2_06411 |
| UGT3A2 | HuMAP2_01019 HuMAP2_02434 HuMAP2_02672 HuMAP2_02760 |
| ACAT1 | HuMAP2_01019 HuMAP2_02434 HuMAP2_02672 HuMAP2_02760 |
| CRIPT | HuMAP2_00125 HuMAP2_00526 HuMAP2_01019 HuMAP2_02760 HuMAP2_04392 |