hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01037
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MTERF3 | Transcription termination factor 3, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3) (mTERF domain-containing protein 1, mitochondrial) | UniProt NCBI |
| NGRN | Neugrin (Mesenchymal stem cell protein DSC92) (Neurite outgrowth-associated protein) (Spinal cord-derived protein FI58G) | UniProt NCBI |
| FASTKD2 | FAST kinase domain-containing protein 2, mitochondrial | UniProt NCBI |
| PTCD1 | Pentatricopeptide repeat-containing protein 1, mitochondrial | UniProt NCBI |
| APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP) | UniProt NCBI |
| YARS2 | Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) | UniProt NCBI |
| TRUB2 | Mitochondrial mRNA pseudouridine synthase TRUB2 (EC 5.4.99.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032543 | 5.45016298593e-05 | 0.714285714286 | MTERF3 NGRN FASTKD2 YARS2 TRUB2 | mitochondrial translation |
| GO:0140053 | 0.000134374214392 | 0.714285714286 | MTERF3 NGRN FASTKD2 YARS2 TRUB2 | mitochondrial gene expression |
| GO:0070131 | 0.00144279242783 | 0.428571428571 | NGRN FASTKD2 TRUB2 | positive regulation of mitochondrial translation |
| GO:0070129 | 0.00487641079113 | 0.428571428571 | NGRN FASTKD2 TRUB2 | regulation of mitochondrial translation |
| GO:0062125 | 0.00640641290662 | 0.428571428571 | NGRN FASTKD2 TRUB2 | regulation of mitochondrial gene expression |
| GO:0006412 | 0.0466952219065 | 0.714285714286 | MTERF3 NGRN FASTKD2 YARS2 TRUB2 | translation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| APIP | FASTKD2 | 0.38 | 0.548 | bioplex (APIP) bioplex_WMM |
| MTERF3 | NGRN | 0.056 | 0.315 | hein_WMM bioplex_WMM WMM_only |
| TRUB2 | YARS2 | 0.055 | 0.309 | hein_WMM bioplex (TRUB2) bioplex_WMM |
| MTERF3 | PTCD1 | 0.051 | 0.301 | bioplex_WMM WMM_only treiber_WMM |
| FASTKD2 | YARS2 | 0.035 | 0.261 | hein_WMM bioplex (FASTKD2) bioplex_WMM youn_WMM |
| FASTKD2 | MTERF3 | 0.029 | 0.232 | hein_WMM bioplex (FASTKD2) bioplex_WMM treiber_WMM |
| PTCD1 | NGRN | 0.027 | 0.225 | bioplex_WMM WMM_only |
| TRUB2 | FASTKD2 | 0.025 | 0.211 | hein_WMM bioplex (FASTKD2) bioplex_WMM treiber_WMM |
| FASTKD2 | PTCD1 | 0.023 | 0.211 | bioplex (FASTKD2) bioplex_WMM treiber_WMM |
| FASTKD2 | NGRN | 0.022 | 0.2 | hein_WMM bioplex (FASTKD2) bioplex_WMM youn_WMM |
| TRUB2 | NGRN | 0.021 | 0.186 | hein_WMM bioplex_WMM WMM_only |
| TRUB2 | MTERF3 | 0.018 | 0.177 | hein_WMM bioplex_WMM WMM_only treiber_WMM |
| TRUB2 | PTCD1 | 0.016 | 0.164 | bioplex_WMM WMM_only treiber_WMM |
| NGRN | YARS2 | 0.015 | 0.141 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| MTERF3 | YARS2 | 0.014 | 0.137 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| PTCD1 | YARS2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01037 has an average edge precision of 0.231 which is ranked 5669 out of all 6965 complexes.
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