hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01047
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYTL2 | Synaptotagmin-like protein 2 (Breast cancer-associated antigen SGA-72M) (Exophilin-4) | UniProt NCBI |
| SYTL1 | Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) | UniProt NCBI |
| SYTL5 | Synaptotagmin-like protein 5 | UniProt NCBI |
| RAB27B | Ras-related protein Rab-27B (C25KG) | UniProt NCBI |
| SYTL4 | Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2291 | 1.82224885556e-14 | 1.0 | SYTL5 SYTL2 SYTL1 SYTL4 RAB27B | Deregulation of Rab and Rab Effector Genes in Bladder Cancer |
| GO:0030133 | 5.32299875625e-05 | 1.0 | SYTL5 SYTL2 SYTL1 SYTL4 RAB27B | transport vesicle |
| GO:0042043 | 7.62415024416e-05 | 0.6 | SYTL2 SYTL1 SYTL4 | neurexin family protein binding |
| GO:0070382 | 0.00113692677057 | 0.8 | SYTL5 SYTL2 SYTL1 SYTL4 | exocytic vesicle |
| GO:0042470 | 0.00139593056214 | 0.6 | RAB27B SYTL1 SYTL2 | melanosome |
| GO:0048770 | 0.00139593056214 | 0.6 | RAB27B SYTL1 SYTL2 | pigment granule |
| GO:0099503 | 0.0133932722999 | 1.0 | SYTL5 SYTL2 SYTL1 SYTL4 RAB27B | secretory vesicle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB27B | SYTL2 | 1.0 | 0.949 | bioplex (RAB27B) bioplex_WMM |
| SYTL1 | RAB27B | 0.999 | 0.949 | bioplex (RAB27B) bioplex_WMM |
| RAB27B | SYTL4 | 0.999 | 0.948 | bioplex (RAB27B) bioplex_WMM |
| SYTL5 | RAB27B | 0.998 | 0.939 | bioplex (RAB27B) bioplex_WMM |
| SYTL5 | SYTL1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL1 | SYTL2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL5 | SYTL2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL4 | SYTL2 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| SYTL1 | SYTL4 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| SYTL5 | SYTL4 | 0.008 | 0.087 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01047 has an average edge precision of 0.433 which is ranked 2990 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SYTL2 | HuMAP2_01047 HuMAP2_01611 |
| SYTL1 | HuMAP2_01047 HuMAP2_01611 |
| SYTL5 | HuMAP2_01047 HuMAP2_01611 |
| RAB27B | HuMAP2_01047 HuMAP2_01611 |
| SYTL4 | HuMAP2_01047 HuMAP2_01394 HuMAP2_01766 HuMAP2_05083 HuMAP2_06001 |