hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01074
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NLRP11 | NACHT, LRR and PYD domains-containing protein 11 (Nucleotide-binding oligomerization domain protein 17) (PAAD-and NACHT domain-containing protein 10) (PYRIN-containing APAF1-like protein 6) | UniProt NCBI |
| SPTBN5 | Spectrin beta chain, non-erythrocytic 5 (Beta-V spectrin) | UniProt NCBI |
| IMPA1 | Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1) | UniProt NCBI |
| MAN2A1 | Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) | UniProt NCBI |
| GSTO2 | Glutathione S-transferase omega-2 (GSTO-2) (EC 2.5.1.18) (Glutathione S-transferase omega 2-2) (GSTO 2-2) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) | UniProt NCBI |
| CTSZ | Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-948021 | 0.00458915535708 | 0.5 | CTSZ MAN2A1 SPTBN5 | Transport to the Golgi and subsequent modification |
| REAC:R-HSA-446203 | 0.0217812337664 | 0.5 | CTSZ MAN2A1 SPTBN5 | Asparagine N-linked glycosylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IMPA1 | GSTO2 | 0.303 | 0.497 | Guru fraction |
| IMPA1 | CTSZ | 0.028 | 0.23 | bioplex (CTSZ) bioplex_WMM fraction |
| IMPA1 | MAN2A1 | 0.026 | 0.22 | fraction |
| MAN2A1 | GSTO2 | 0.023 | 0.207 | fraction |
| IMPA1 | SPTBN5 | 0.023 | 0.209 | fraction |
| NLRP11 | SPTBN5 | 0.022 | 0.205 | fraction |
| MAN2A1 | CTSZ | 0.006 | 0.012 | fraction |
Images
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Complex HuMAP2_01074 has an average edge precision of 0.226 which is ranked 5763 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NLRP11 | HuMAP2_00770 HuMAP2_01074 HuMAP2_02195 HuMAP2_05275 |
| SPTBN5 | HuMAP2_01074 HuMAP2_02195 |
| IMPA1 | HuMAP2_00332 HuMAP2_01074 HuMAP2_01864 HuMAP2_06793 |
| MAN2A1 | HuMAP2_00753 HuMAP2_01074 HuMAP2_02004 HuMAP2_05613 |
| GSTO2 | HuMAP2_01074 HuMAP2_01418 HuMAP2_04777 HuMAP2_06652 HuMAP2_06793 |
| CTSZ | HuMAP2_01074 HuMAP2_02706 HuMAP2_03122 |