hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01081
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CD44 | CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44) | UniProt NCBI |
| VCAN | Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) | UniProt NCBI |
| METTL8 | Methyltransferase-like protein 8 (EC 2.1.1.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005540 | 0.0283955176165 | 0.666666666667 | VCAN CD44 | hyaluronic acid binding |
| REAC:R-HSA-1630316 | 0.0406759452204 | 0.666666666667 | VCAN CD44 | Glycosaminoglycan metabolism |
| CORUM:7535 | 0.0499776345577 | 0.333333333333 | CD44 | CD44-LRP1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VCAN | CD44 | 0.198 | 0.451 | bioplex (CD44) bioplex_WMM |
| CD44 | METTL8 | 0.048 | 0.295 | bioplex (CD44) bioplex_WMM |
| VCAN | METTL8 | 0.008 | 0.012 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01081 has an average edge precision of 0.253 which is ranked 5342 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CD44 | HuMAP2_01081 HuMAP2_03996 |
| VCAN | HuMAP2_01081 HuMAP2_06568 |
| METTL8 | HuMAP2_01081 HuMAP2_03996 HuMAP2_06989 |