hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01088
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBBP6 | E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis) | UniProt NCBI |
| CWC22 | Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb) | UniProt NCBI |
| ACIN1 | Apoptotic chromatin condensation inducer in the nucleus (Acinus) | UniProt NCBI |
| GPATCH8 | G patch domain-containing protein 8 | UniProt NCBI |
| FNBP4 | Formin-binding protein 4 (Formin-binding protein 30) | UniProt NCBI |
| UBTF | Nucleolar transcription factor 1 (Autoantigen NOR-90) (Upstream-binding factor 1) (UBF-1) | UniProt NCBI |
| PNN | Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) | UniProt NCBI |
| TOPORS | E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3) | UniProt NCBI |
| ZC3H18 | Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1) | UniProt NCBI |
| SAP18 | Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18) | UniProt NCBI |
| NKAPD1 | Uncharacterized protein NKAPD1 (NKAP domain containing protein 1) | UniProt NCBI |
| RNPS1 | RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2) | UniProt NCBI |
| SNIP1 | Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1) | UniProt NCBI |
| ZC3H14 | Zinc finger CCCH domain-containing protein 14 (Mammalian suppressor of tau pathology-2) (MSUT-2) (Renal carcinoma antigen NY-REN-37) | UniProt NCBI |
| CCDC9 | Coiled-coil domain-containing protein 9 | UniProt NCBI |
| NKTR | NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:760 | 4.70911134935e-08 | 0.1875 | ACIN1 SAP18 RNPS1 | Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18, RNPS1, Acinus-L |
| GO:0016607 | 1.8614811996e-07 | 0.5625 | ACIN1 TOPORS ZC3H18 SAP18 FNBP4 CWC22 ZC3H14 PNN RBBP6 | nuclear speck |
| GO:0003723 | 3.6763794621e-05 | 0.75 | ACIN1 CCDC9 ZC3H18 SAP18 GPATCH8 CWC22 ZC3H14 PNN UBTF RBBP6 RNPS1 SNIP1 | RNA binding |
| KEGG:03015 | 0.000102906156656 | 0.25 | PNN ACIN1 SAP18 RNPS1 | mRNA surveillance pathway |
| GO:0016604 | 0.000129514180815 | 0.5625 | ACIN1 TOPORS ZC3H18 SAP18 FNBP4 CWC22 ZC3H14 PNN RBBP6 | nuclear body |
| GO:0061574 | 0.000203300410527 | 0.1875 | ACIN1 SAP18 RNPS1 | ASAP complex |
| KEGG:03013 | 0.0009286637701 | 0.25 | PNN ACIN1 SAP18 RNPS1 | RNA transport |
| GO:0003676 | 0.00157209695664 | 0.8125 | ACIN1 CCDC9 ZC3H18 SAP18 GPATCH8 TOPORS CWC22 ZC3H14 PNN UBTF RBBP6 RNPS1 SNIP1 | nucleic acid binding |
| GO:0044451 | 0.00481232843516 | 0.5625 | ACIN1 TOPORS ZC3H18 SAP18 FNBP4 CWC22 ZC3H14 PNN RBBP6 | nucleoplasm part |
| CORUM:351 | 0.0192670275368 | 0.1875 | CWC22 RNPS1 ACIN1 | Spliceosome |
| GO:1901363 | 0.0244061537502 | 0.8125 | ACIN1 CCDC9 ZC3H18 SAP18 GPATCH8 TOPORS CWC22 ZC3H14 PNN UBTF RBBP6 RNPS1 SNIP1 | heterocyclic compound binding |
| GO:0005654 | 0.0280611116533 | 0.8125 | ACIN1 TOPORS PNN ZC3H18 SAP18 RNPS1 CWC22 ZC3H14 UBTF NKTR RBBP6 FNBP4 SNIP1 | nucleoplasm |
| GO:0097159 | 0.0301852443301 | 0.8125 | ACIN1 CCDC9 ZC3H18 SAP18 GPATCH8 TOPORS CWC22 ZC3H14 PNN UBTF RBBP6 RNPS1 SNIP1 | organic cyclic compound binding |
| GO:0035145 | 0.0487679991073 | 0.1875 | PNN SAP18 RNPS1 | exon-exon junction complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACIN1 | PNN | 0.999 | 0.949 | hein_WMM bioplex (PNN) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| RNPS1 | ACIN1 | 0.997 | 0.931 | bioplex_WMM youn_WMM gupta_WMM fraction |
| RNPS1 | PNN | 0.994 | 0.923 | bioplex (PNN) bioplex_WMM youn_WMM gupta_WMM fraction |
| CCDC9 | PNN | 0.986 | 0.901 | hein_WMM bioplex (PNN) bioplex_WMM youn_WMM hein (CCDC9) |
| GPATCH8 | RNPS1 | 0.746 | 0.741 | bioplex_WMM youn_WMM hein (RNPS1) gupta_WMM fraction |
| ACIN1 | SNIP1 | 0.659 | 0.696 | bioplex (SNIP1) bioplex_WMM |
| CCDC9 | ACIN1 | 0.63 | 0.681 | hein_WMM bioplex_WMM youn_WMM hein (CCDC9) |
| ZC3H14 | PNN | 0.441 | 0.584 | bioplex (PNN) bioplex_WMM youn_WMM gupta_WMM |
| ZC3H18 | RNPS1 | 0.389 | 0.551 | bioplex (ZC3H18) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| ACIN1 | UBTF | 0.359 | 0.54 | bioplex_WMM youn_WMM gupta_WMM fraction |
| RNPS1 | SNIP1 | 0.286 | 0.489 | bioplex (SNIP1) bioplex_WMM |
| SAP18 | CCDC9 | 0.278 | 0.486 | hein_WMM bioplex_WMM youn_WMM hein (CCDC9) |
| ZC3H18 | RBBP6 | 0.261 | 0.482 | hein_WMM bioplex (ZC3H18) bioplex_WMM youn_WMM gupta_WMM |
| SNIP1 | ZC3H14 | 0.137 | 0.408 | bioplex (SNIP1) bioplex_WMM |
| ZC3H18 | FNBP4 | 0.127 | 0.398 | bioplex (ZC3H18) bioplex_WMM youn_WMM |
| CCDC9 | NKTR | 0.103 | 0.366 | hein_WMM bioplex_WMM hein (CCDC9) |
| ZC3H18 | ACIN1 | 0.099 | 0.358 | bioplex (ZC3H18) bioplex_WMM youn_WMM gupta_WMM fraction |
| ZC3H18 | CWC22 | 0.07 | 0.347 | bioplex_WMM youn_WMM fraction |
| ZC3H18 | TOPORS | 0.057 | 0.322 | bioplex (ZC3H18) bioplex_WMM |
| ZC3H18 | PNN | 0.047 | 0.293 | bioplex (ZC3H18) bioplex_WMM youn_WMM gupta_WMM fraction |
| NKAPD1 | ZC3H14 | 0.047 | 0.293 | bioplex (NKAPD1) bioplex_WMM |
| SNIP1 | PNN | 0.039 | 0.266 | bioplex (SNIP1) bioplex_WMM |
| RNPS1 | UBTF | 0.039 | 0.264 | bioplex_WMM youn_WMM gupta_WMM fraction |
| CCDC9 | SNIP1 | 0.032 | 0.241 | bioplex (SNIP1) bioplex_WMM |
| ZC3H18 | ZC3H14 | 0.029 | 0.234 | bioplex (ZC3H18) bioplex_WMM youn_WMM |
| CWC22 | PNN | 0.029 | 0.231 | bioplex_WMM youn_WMM fraction treiber_WMM |
| RNPS1 | ZC3H14 | 0.022 | 0.196 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NKAPD1 | NKTR | 0.021 | 0.185 | bioplex (NKAPD1) bioplex_WMM |
| NKAPD1 | RNPS1 | 0.02 | 0.188 | bioplex (NKAPD1) bioplex_WMM |
| CCDC9 | ZC3H14 | 0.019 | 0.182 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| ACIN1 | ZC3H14 | 0.016 | 0.164 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NKTR | PNN | 0.016 | 0.161 | hein_WMM bioplex (PNN) bioplex_WMM |
| NKAPD1 | ACIN1 | 0.015 | 0.145 | bioplex (NKAPD1) bioplex_WMM |
| CCDC9 | RNPS1 | 0.012 | 0.145 | bioplex_WMM youn_WMM WMM_only |
| GPATCH8 | PNN | 0.011 | 0.141 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZC3H18 | NKTR | 0.011 | 0.144 | bioplex (ZC3H18) bioplex_WMM boldt_WMM |
| RBBP6 | PNN | 0.01 | 0.14 | bioplex (PNN) bioplex_WMM youn_WMM gupta_WMM |
| NKAPD1 | PNN | 0.01 | 0.134 | bioplex (NKAPD1) bioplex_WMM |
| RNPS1 | RBBP6 | 0.01 | 0.134 | bioplex_WMM youn_WMM gupta_WMM fraction |
| NKTR | TOPORS | 0.01 | 0.133 | bioplex_WMM WMM_only |
| GPATCH8 | ZC3H14 | 0.01 | 0.13 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NKTR | ACIN1 | 0.01 | 0.107 | hein_WMM bioplex_WMM WMM_only |
| ZC3H14 | RBBP6 | 0.01 | 0.105 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SAP18 | SNIP1 | 0.009 | 0.111 | bioplex (SNIP1) bioplex_WMM |
| NKTR | ZC3H14 | 0.009 | 0.103 | bioplex_WMM WMM_only |
| NKTR | RBBP6 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| SAP18 | GPATCH8 | 0.009 | 0.098 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RBBP6 | TOPORS | 0.008 | 0.093 | bioplex_WMM WMM_only |
| SAP18 | ZC3H14 | 0.008 | 0.09 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NKTR | GPATCH8 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| FNBP4 | RBBP6 | 0.008 | 0.085 | bioplex_WMM youn_WMM WMM_only |
| ZC3H18 | GPATCH8 | 0.008 | 0.084 | bioplex_WMM youn_WMM fraction boldt_WMM |
| CCDC9 | GPATCH8 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| GPATCH8 | RBBP6 | 0.008 | 0.082 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZC3H14 | FNBP4 | 0.008 | 0.044 | bioplex_WMM youn_WMM WMM_only |
| NKTR | RNPS1 | 0.008 | 0.041 | bioplex_WMM WMM_only boldt_WMM |
| SAP18 | NKTR | 0.008 | 0.039 | hein_WMM bioplex_WMM WMM_only |
| NKAPD1 | CCDC9 | 0.008 | 0.029 | bioplex (NKAPD1) bioplex_WMM |
| ACIN1 | CWC22 | 0.008 | 0.027 | bioplex_WMM youn_WMM fraction treiber_WMM |
| FNBP4 | PNN | 0.008 | 0.019 | bioplex_WMM youn_WMM WMM_only |
| NKTR | FNBP4 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| ZC3H14 | UBTF | 0.008 | 0.014 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CCDC9 | CWC22 | 0.008 | 0.008 | bioplex_WMM WMM_only |
| FNBP4 | TOPORS | 0.007 | 0.006 | bioplex_WMM WMM_only |
| SAP18 | RBBP6 | 0.007 | 0.011 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CCDC9 | UBTF | 0.007 | 0.011 | bioplex_WMM WMM_only |
| UBTF | RBBP6 | 0.007 | 0.005 | youn_WMM gupta_WMM WMM_only treiber_WMM |
| FNBP4 | UBTF | 0.007 | 0.011 | youn_WMM WMM_only |
| GPATCH8 | FNBP4 | 0.007 | 0.008 | youn_WMM WMM_only |
| RNPS1 | FNBP4 | 0.007 | 0.006 | bioplex_WMM youn_WMM WMM_only |
| NKAPD1 | UBTF | 0.007 | 0.008 | bioplex (NKAPD1) bioplex_WMM |
| ACIN1 | FNBP4 | 0.007 | 0.004 | bioplex_WMM youn_WMM WMM_only |
| CWC22 | RBBP6 | 0.007 | 0.005 | youn_WMM WMM_only |
| CWC22 | FNBP4 | 0.007 | 0.007 | youn_WMM WMM_only |
| SAP18 | FNBP4 | 0.007 | 0.003 | youn_WMM WMM_only |
| CCDC9 | RBBP6 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| NKTR | UBTF | 0.007 | 0.003 | bioplex_WMM WMM_only |
| ZC3H14 | TOPORS | 0.007 | 0.001 | bioplex_WMM WMM_only |
| GPATCH8 | TOPORS | 0.007 | 0.002 | bioplex_WMM WMM_only |
| CCDC9 | TOPORS | 0.007 | 0.004 | bioplex_WMM WMM_only |
| ZC3H18 | NKAPD1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| CWC22 | ZC3H14 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| ZC3H18 | CCDC9 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| NKTR | CWC22 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| ACIN1 | TOPORS | 0.007 | 0.007 | bioplex_WMM youn_WMM WMM_only |
| SAP18 | TOPORS | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| RNPS1 | TOPORS | 0.007 | 0.001 | bioplex_WMM youn_WMM WMM_only |
| NKAPD1 | SAP18 | 0.006 | 0.003 | bioplex (NKAPD1) bioplex_WMM |
| NKTR | SNIP1 | 0.006 | 0.006 | bioplex (SNIP1) bioplex_WMM |
| GPATCH8 | ACIN1 | 0.005 | 0.013 | bioplex_WMM youn_WMM gupta_WMM fraction |
| NKAPD1 | CWC22 | 0.004 | 0.012 | bioplex (NKAPD1) bioplex_WMM |
| ZC3H18 | UBTF | 0.004 | 0.011 | bioplex_WMM youn_WMM gupta_WMM fraction |
| SAP18 | RNPS1 | 0.003 | 0.013 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| GPATCH8 | UBTF | 0.003 | 0.01 | bioplex_WMM youn_WMM gupta_WMM fraction |
| PNN | TOPORS | 0.003 | 0.013 | bioplex (PNN) bioplex_WMM |
| SAP18 | CWC22 | 0.003 | 0.014 | bioplex_WMM youn_WMM fraction |
| ACIN1 | RBBP6 | 0.0 | 0.014 | bioplex_WMM youn_WMM gupta_WMM fraction |
| RNPS1 | CWC22 | 0.0 | 0.016 | bioplex_WMM youn_WMM fraction |
| UBTF | PNN | 0.0 | 0.009 | bioplex_WMM youn_WMM gupta_WMM fraction |
| SAP18 | ACIN1 | 0.0 | 0.007 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| GPATCH8 | CWC22 | 0.0 | 0.011 | bioplex_WMM youn_WMM fraction |
| CWC22 | UBTF | 0.0 | 0.01 | bioplex_WMM youn_WMM fraction boldt_WMM |
| SAP18 | UBTF | 0.0 | 0.008 | bioplex_WMM youn_WMM gupta_WMM fraction |
| GPATCH8 | SNIP1 | 0.0 | 0.012 | bioplex (SNIP1) bioplex_WMM |
| CWC22 | SNIP1 | 0.0 | 0.001 | bioplex (SNIP1) bioplex_WMM |
| ZC3H18 | SAP18 | 0.0 | 0.001 | bioplex (ZC3H18) bioplex_WMM youn_WMM gupta_WMM fraction |
| ZC3H18 | SNIP1 | 0.0 | 0.001 | hein_WMM bioplex (SNIP1) bioplex_WMM |
| SAP18 | PNN | 0.0 | 0.001 | hein_WMM bioplex (PNN) bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_01088 has an average edge precision of 0.158 which is ranked 6646 out of all 6965 complexes.
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