hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01108
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BUD23 | Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Metastasis-related methyltransferase 1) (Williams-Beuren syndrome chromosomal region 22 protein) (rRNA methyltransferase and ribosome maturation factor) | UniProt NCBI |
| TRMT112 | Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070476 | 0.000450823411379 | 1.0 | BUD23 TRMT112 | rRNA (guanine-N7)-methylation |
| GO:0036265 | 0.00135247023414 | 1.0 | BUD23 TRMT112 | RNA (guanine-N7)-methylation |
| REAC:R-HSA-6790901 | 0.0029663845284 | 1.0 | BUD23 TRMT112 | rRNA modification in the nucleus and cytosol |
| GO:0016435 | 0.00450823411379 | 1.0 | BUD23 TRMT112 | rRNA (guanine) methyltransferase activity |
| GO:0070475 | 0.0126230555186 | 1.0 | BUD23 TRMT112 | rRNA base methylation |
| GO:0090070 | 0.0162296428096 | 1.0 | BUD23 TRMT112 | positive regulation of ribosome biogenesis |
| GO:2000234 | 0.0162296428096 | 1.0 | BUD23 TRMT112 | positive regulation of rRNA processing |
| GO:2000232 | 0.029754345151 | 1.0 | BUD23 TRMT112 | regulation of rRNA processing |
| REAC:R-HSA-8868773 | 0.0304096312248 | 1.0 | BUD23 TRMT112 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.0336860615937 | 1.0 | BUD23 TRMT112 | rRNA processing |
| GO:0090069 | 0.0351642260875 | 1.0 | BUD23 TRMT112 | regulation of ribosome biogenesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BUD23 | TRMT112 | 0.373 | 0.546 | hein_WMM bioplex (BUD23) bioplex_WMM fraction |
Images
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Complex HuMAP2_01108 has an average edge precision of 0.546 which is ranked 2221 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BUD23 | HuMAP2_01108 HuMAP2_01987 HuMAP2_02860 |
| TRMT112 | HuMAP2_01108 HuMAP2_01987 HuMAP2_02860 |