hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01114
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| AP2M1 | AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein) | UniProt NCBI |
| AAK1 | AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8856825 | 0.00656291627866 | 1.0 | AAK1 AP2M1 | Cargo recognition for clathrin-mediated endocytosis |
| REAC:R-HSA-8856828 | 0.0138364241054 | 1.0 | AAK1 AP2M1 | Clathrin-mediated endocytosis |
| REAC:R-HSA-164939 | 0.0249595281251 | 0.5 | AP2M1 | Nef mediated downregulation of CD28 cell surface expression |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AAK1 | AP2M1 | 1.0 | 0.949 | hein_WMM bioplex (AP2M1) bioplex_WMM youn_WMM gupta_WMM |
Images
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Complex HuMAP2_01114 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| AP2M1 | HuMAP2_01005 HuMAP2_01114 HuMAP2_03002 HuMAP2_03989 HuMAP2_06613 HuMAP2_06848 |
| AAK1 | HuMAP2_00998 HuMAP2_01005 HuMAP2_01114 HuMAP2_02595 HuMAP2_03002 HuMAP2_06069 HuMAP2_06613 |