hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01126
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DYNLRB2 | Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) (Roadblock domain-containing protein 2) | UniProt NCBI |
| ENO1 | Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein) | UniProt NCBI |
| FKBP7 | Peptidyl-prolyl cis-trans isomerase FKBP7 (PPIase FKBP7) (EC 5.2.1.8) (23 kDa FK506-binding protein) (23 kDa FKBP) (FKBP-23) (FK506-binding protein 7) (FKBP-7) (Rotamase) | UniProt NCBI |
| YKT6 | Synaptobrevin homolog YKT6 (EC 2.3.1.-) | UniProt NCBI |
| ENO3 | Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase) | UniProt NCBI |
| SPR | Sepiapterin reductase (SPR) (EC 1.1.1.153) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP534 | 0.00524729006009 | 0.333333333333 | ENO1 ENO3 | Glycolysis and Gluconeogenesis |
| REAC:R-HSA-70263 | 0.00959640616298 | 0.333333333333 | ENO1 ENO3 | Gluconeogenesis |
| KEGG:00010 | 0.0120956152943 | 0.333333333333 | ENO1 ENO3 | Glycolysis / Gluconeogenesis |
| KEGG:01230 | 0.0153684049392 | 0.333333333333 | ENO1 ENO3 | Biosynthesis of amino acids |
| WP:WP4018 | 0.0174151198914 | 0.333333333333 | ENO1 ENO3 | Pathways in clear cell renal cell carcinoma |
| KEGG:03018 | 0.0176099294651 | 0.333333333333 | ENO1 ENO3 | RNA degradation |
| GO:0004634 | 0.020283420769 | 0.333333333333 | ENO1 ENO3 | phosphopyruvate hydratase activity |
| KEGG:04066 | 0.0304541793376 | 0.333333333333 | ENO1 ENO3 | HIF-1 signaling pathway |
| KEGG:01200 | 0.039527830217 | 0.333333333333 | ENO1 ENO3 | Carbon metabolism |
| REAC:R-HSA-70171 | 0.0470157324282 | 0.333333333333 | ENO1 ENO3 | Glycolysis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| YKT6 | ENO1 | 0.946 | 0.857 | bioplex (YKT6) bioplex_WMM fraction treiber_WMM |
| FKBP7 | ENO1 | 0.285 | 0.49 | bioplex (FKBP7) bioplex_WMM Guru fraction |
| YKT6 | ENO3 | 0.119 | 0.393 | bioplex (YKT6) fraction |
| SPR | ENO1 | 0.071 | 0.352 | fraction treiber_WMM |
| DYNLRB2 | ENO3 | 0.042 | 0.27 | fraction |
| DYNLRB2 | ENO1 | 0.041 | 0.268 | fraction |
| ENO3 | ENO1 | 0.034 | 0.261 | bioplex (ENO3) bioplex_WMM boldt_WMM treiber_WMM |
| YKT6 | DYNLRB2 | 0.007 | 0.003 | gupta_WMM WMM_only |
| SPR | YKT6 | 0.006 | 0.006 | fraction treiber_WMM |
| SPR | ENO3 | 0.0 | 0.002 | fraction |
Images
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Complex HuMAP2_01126 has an average edge precision of 0.29 which is ranked 4747 out of all 6965 complexes.
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