hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01150
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| INTS6L | Integrator complex subunit 6-like (Protein DDX26B) | UniProt NCBI |
| CSTF2 | Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64) | UniProt NCBI |
| CSTF1 | Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1146 | 1.00675659188e-05 | 0.666666666667 | CSTF2 CSTF1 | Cleavage stimulation factor |
| CORUM:2211 | 3.35555483123e-05 | 0.666666666667 | CSTF2 CSTF1 | BARD1-BRCA1-CSTF complex |
| CORUM:1147 | 7.04603414803e-05 | 0.666666666667 | CSTF2 CSTF1 | Polyadenylation complex (CSTF1, CSTF2, CSTF3, SYMPK CPSF1, CPSF2, CPSF3) |
| REAC:R-HSA-77595 | 0.00114404160216 | 0.666666666667 | CSTF2 CSTF1 | Processing of Intronless Pre-mRNAs |
| KEGG:03015 | 0.0017077231529 | 0.666666666667 | CSTF2 CSTF1 | mRNA surveillance pathway |
| REAC:R-HSA-75067 | 0.00252791438215 | 0.666666666667 | CSTF2 CSTF1 | Processing of Capped Intronless Pre-mRNA |
| WP:WP411 | 0.00739285752446 | 0.666666666667 | CSTF2 CSTF1 | mRNA Processing |
| REAC:R-HSA-72187 | 0.00955880978777 | 0.666666666667 | CSTF2 CSTF1 | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 0.0130404028432 | 0.666666666667 | CSTF2 CSTF1 | RNA Polymerase II Transcription Termination |
| GO:0031123 | 0.0356085105614 | 1.0 | INTS6L CSTF2 CSTF1 | RNA 3'-end processing |
| MIRNA:hsa-miR-4738-3p | 0.0467934390182 | 0.666666666667 | CSTF2 CSTF1 | hsa-miR-4738-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CSTF2 | CSTF1 | 0.399 | 0.559 | hein_WMM bioplex_WMM Guru youn_WMM Malo fraction treiber_WMM |
| CSTF2 | INTS6L | 0.042 | 0.269 | fraction |
Images
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Complex HuMAP2_01150 has an average edge precision of 0.414 which is ranked 3161 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| INTS6L | HuMAP2_01150 HuMAP2_02956 HuMAP2_06201 |
| CSTF2 | HuMAP2_01150 HuMAP2_02956 HuMAP2_06228 |
| CSTF1 | HuMAP2_01150 HuMAP2_01726 HuMAP2_02956 |