hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01156
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| H1-3 | Histone H1.3 (Histone H1c) (Histone H1s-2) | UniProt NCBI |
| H1-2 | Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1) | UniProt NCBI |
| H2AFX | Histone H2AX (H2a/x) (Histone H2A.X) | UniProt NCBI |
| RPL28 | 60S ribosomal protein L28 (Large ribosomal subunit protein eL28) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2559586 | 0.000106384407537 | 0.75 | H2AFX H1-3 H1-2 | DNA Damage/Telomere Stress Induced Senescence |
| REAC:R-HSA-140342 | 0.000783559910601 | 0.5 | H1-3 H1-2 | Apoptosis induced DNA fragmentation |
| REAC:R-HSA-2559584 | 0.00120515287053 | 0.5 | H1-3 H1-2 | Formation of Senescence-Associated Heterochromatin Foci (SAHF) |
| REAC:R-HSA-2559583 | 0.00145806857207 | 0.75 | H2AFX H1-3 H1-2 | Cellular Senescence |
| REAC:R-HSA-75153 | 0.012764635731 | 0.5 | H1-3 H1-2 | Apoptotic execution phase |
| REAC:R-HSA-2262752 | 0.0147563350021 | 0.75 | H2AFX H1-3 H1-2 | Cellular responses to stress |
| REAC:R-HSA-8953897 | 0.0253615474256 | 0.75 | H2AFX H1-3 H1-2 | Cellular responses to external stimuli |
| CORUM:3055 | 0.0256667490118 | 0.5 | RPL28 H1-3 | Nop56p-associated pre-rRNA complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| H1-3 | RPL28 | 0.885 | 0.817 | bioplex (RPL28) bioplex_WMM boldt gupta_WMM boldt_WMM treiber_WMM |
| RPL28 | 728912 | 0.286 | 0.489 | bioplex (RPL28) bioplex_WMM |
| RPL28 | H1-2 | 0.204 | 0.454 | bioplex (RPL28) bioplex_WMM boldt gupta_WMM boldt_WMM treiber_WMM |
| H2AFX | H1-2 | 0.064 | 0.349 | bioplex (H2AFX) bioplex_WMM youn_WMM gupta_WMM |
| H1-3 | H1-2 | 0.009 | 0.109 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM treiber_WMM |
| H1-3 | 728912 | 0.008 | 0.059 | bioplex_WMM WMM_only |
| H1-2 | 728912 | 0.008 | 0.032 | bioplex_WMM WMM_only |
| H1-3 | H2AFX | 0.007 | 0.003 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| H2AFX | RPL28 | 0.007 | 0.005 | hein_WMM bioplex_WMM gupta_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_01156 has an average edge precision of 0.257 which is ranked 5267 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| H1-3 | HuMAP2_00380 HuMAP2_01156 HuMAP2_01921 HuMAP2_03549 HuMAP2_04252 HuMAP2_05025 |
| H1-2 | HuMAP2_01156 HuMAP2_01571 |
| H2AFX | HuMAP2_00547 HuMAP2_01156 HuMAP2_02818 HuMAP2_03709 HuMAP2_06596 |
| RPL28 | HuMAP2_01156 HuMAP2_02207 HuMAP2_04416 |