hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01163
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RTCB | tRNA-splicing ligase RtcB homolog (EC 6.5.1.3) | UniProt NCBI |
| GART | Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] | UniProt NCBI |
| DDX1 | ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6301 | 3.35555483123e-05 | 0.666666666667 | DDX1 RTCB | tRNA Splicing Ligase Complex |
| REAC:R-HSA-6784531 | 0.00955880978777 | 0.666666666667 | DDX1 RTCB | tRNA processing in the nucleus |
| REAC:R-HSA-72306 | 0.0343335993912 | 0.666666666667 | DDX1 RTCB | tRNA processing |
| GO:0072669 | 0.0378589948753 | 0.666666666667 | DDX1 RTCB | tRNA-splicing ligase complex |
| WP:WP2942 | 0.0499785733994 | 0.333333333333 | DDX1 | DDX1 as a regulatory component of the Drosha microprocessor |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX1 | RTCB | 1.0 | 0.949 | hein_WMM youn (DDX1) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| DDX1 | GART | 0.067 | 0.35 | youn (DDX1) bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| RTCB | GART | 0.065 | 0.347 | bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_01163 has an average edge precision of 0.549 which is ranked 2204 out of all 6965 complexes.
Related Complexes