hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01167
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SMAD4 | Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4) | UniProt NCBI |
| LHX4 | LIM/homeobox protein Lhx4 (LIM homeobox protein 4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000204 | 0.0258806032458 | 1.0 | SMAD4 LHX4 | Cleft upper lip |
| HP:0410030 | 0.0329602005208 | 1.0 | SMAD4 LHX4 | Cleft lip |
| HP:0000952 | 0.0358354520556 | 1.0 | SMAD4 LHX4 | Jaundice |
| HP:0004621 | 0.0497341708567 | 0.5 | SMAD4 | Enlarged vertebral pedicles |
| HP:0030277 | 0.0497341708567 | 0.5 | SMAD4 | Abnormal vertebral pedicle morphology |
| CORUM:2704 | 0.0499173803268 | 0.5 | SMAD4 | Ectodermin-SMAD4 complex |
| CORUM:3038 | 0.0499173803268 | 0.5 | SMAD4 | SMAD2-SMAD4-FAST1 complex |
| CORUM:3200 | 0.0499173803268 | 0.5 | SMAD4 | SMAD4-SKI complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SMAD4 | LHX4 | 0.548 | 0.642 | bioplex (LHX4) bioplex_WMM |
Images
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Complex HuMAP2_01167 has an average edge precision of 0.642 which is ranked 1703 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SMAD4 | HuMAP2_01167 HuMAP2_06632 |
| LHX4 | HuMAP2_01167 HuMAP2_04165 HuMAP2_06632 |