hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01190
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FZR1 | Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1) | UniProt NCBI |
| CDC27 | Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC) | UniProt NCBI |
| ANAPC2 | Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2) | UniProt NCBI |
| ANAPC16 | Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16) | UniProt NCBI |
| CDC26 | Anaphase-promoting complex subunit CDC26 (Anaphase-promoting complex subunit 12) (APC12) (Cell division cycle protein 26 homolog) | UniProt NCBI |
| ANAPC4 | Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4) | UniProt NCBI |
| CDC16 | Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6) | UniProt NCBI |
| ANAPC5 | Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5) | UniProt NCBI |
| ANAPC10 | Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10) | UniProt NCBI |
| CDC23 | Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8) | UniProt NCBI |
| ANAPC1 | Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein) | UniProt NCBI |
| ANAPC7 | Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) | UniProt NCBI |
| ANAPC13 | Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005680 | 1.3670726081e-35 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | anaphase-promoting complex |
| REAC:R-HSA-176407 | 2.33025117074e-34 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| REAC:R-HSA-176412 | 2.9712110911e-30 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Phosphorylation of the APC/C |
| GO:0000152 | 4.50025264788e-30 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | nuclear ubiquitin ligase complex |
| REAC:R-HSA-141430 | 7.0557567123e-30 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Inactivation of APC/C via direct inhibition of the APC/C complex |
| REAC:R-HSA-141405 | 7.0557567123e-30 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| GO:0070979 | 4.55807093323e-29 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | protein K11-linked ubiquitination |
| REAC:R-HSA-174048 | 6.5829382723e-29 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | APC/C:Cdc20 mediated degradation of Cyclin B |
| REAC:R-HSA-179409 | 2.32877314791e-28 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | APC-Cdc20 mediated degradation of Nek2A |
| CORUM:96 | 4.13021456905e-28 | 0.692307692308 | ANAPC2 CDC16 CDC27 CDC23 ANAPC7 ANAPC10 ANAPC4 ANAPC1 ANAPC5 | Anaphase-promoting complex |
| REAC:R-HSA-174084 | 2.70413512719e-26 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Autodegradation of Cdh1 by Cdh1:APC/C |
| REAC:R-HSA-174178 | 1.60178201065e-25 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| REAC:R-HSA-69017 | 1.60178201065e-25 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | CDK-mediated phosphorylation and removal of Cdc6 |
| KEGG:04914 | 1.88397961812e-25 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Progesterone-mediated oocyte maturation |
| REAC:R-HSA-176408 | 6.40377438358e-25 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Regulation of APC/C activators between G1/S and early anaphase |
| CORUM:93 | 1.2296474815e-24 | 0.615384615385 | ANAPC2 CDC16 CDC27 CDC23 ANAPC7 ANAPC4 ANAPC1 ANAPC5 | Anaphase-promoting complex |
| REAC:R-HSA-453276 | 1.64463339692e-24 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Regulation of mitotic cell cycle |
| REAC:R-HSA-174143 | 1.64463339692e-24 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | APC/C-mediated degradation of cell cycle proteins |
| REAC:R-HSA-69052 | 2.96656543785e-24 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Switching of origins to a post-replicative state |
| REAC:R-HSA-2559582 | 2.74746031119e-23 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Senescence-Associated Secretory Phenotype (SASP) |
| KEGG:04110 | 2.80162154947e-23 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Cell cycle |
| KEGG:04120 | 7.65368037176e-23 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Ubiquitin mediated proteolysis |
| REAC:R-HSA-174154 | 9.96881765166e-23 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | APC/C:Cdc20 mediated degradation of Securin |
| REAC:R-HSA-69239 | 1.06430414037e-22 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Synthesis of DNA |
| GO:0031145 | 1.57447704034e-22 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | anaphase-promoting complex-dependent catabolic process |
| REAC:R-HSA-174184 | 2.37503638713e-22 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
| REAC:R-HSA-69306 | 2.42760777646e-22 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | DNA Replication |
| GO:0031461 | 2.69082090874e-22 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | cullin-RING ubiquitin ligase complex |
| REAC:R-HSA-179419 | 2.80297504372e-22 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint |
| REAC:R-HSA-176409 | 3.87555733211e-22 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | APC/C:Cdc20 mediated degradation of mitotic proteins |
| REAC:R-HSA-176814 | 4.54110712803e-22 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
| REAC:R-HSA-69242 | 4.43159382681e-21 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | S Phase |
| KEGG:04114 | 6.095759964e-21 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Oocyte meiosis |
| WP:WP179 | 2.12535516013e-20 | 0.846153846154 | ANAPC2 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Cell Cycle |
| REAC:R-HSA-69618 | 2.86121556205e-20 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Mitotic Spindle Checkpoint |
| REAC:R-HSA-2559583 | 3.53191764727e-20 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Cellular Senescence |
| GO:0000151 | 4.43842056335e-19 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | ubiquitin ligase complex |
| REAC:R-HSA-983168 | 7.87162146714e-18 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Antigen processing: Ubiquitination & Proteasome degradation |
| REAC:R-HSA-2467813 | 1.30020816955e-17 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Separation of Sister Chromatids |
| REAC:R-HSA-68882 | 2.10700753951e-17 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Mitotic Anaphase |
| REAC:R-HSA-2555396 | 2.23477933577e-17 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Mitotic Metaphase and Anaphase |
| REAC:R-HSA-983169 | 6.92212337287e-17 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Class I MHC mediated antigen processing & presentation |
| REAC:R-HSA-2262752 | 4.48556242341e-16 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Cellular responses to stress |
| GO:0000209 | 6.60697034115e-16 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | protein polyubiquitination |
| KEGG:05166 | 1.83536972443e-15 | 0.769230769231 | ANAPC2 CDC16 CDC26 CDC27 CDC23 ANAPC7 ANAPC10 ANAPC4 ANAPC1 ANAPC5 | Human T-cell leukemia virus 1 infection |
| REAC:R-HSA-69620 | 2.02742839516e-15 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | Cell Cycle Checkpoints |
| REAC:R-HSA-8953897 | 4.04925230101e-15 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Cellular responses to external stimuli |
| REAC:R-HSA-69278 | 7.95412322713e-15 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Cell Cycle, Mitotic |
| GO:1901990 | 1.39706820016e-14 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | regulation of mitotic cell cycle phase transition |
| GO:0016567 | 1.61652321421e-14 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | protein ubiquitination |
| GO:0043161 | 2.33459816531e-14 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| GO:1901987 | 3.24881732256e-14 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | regulation of cell cycle phase transition |
| REAC:R-HSA-68886 | 4.22079328256e-14 | 0.846153846154 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 | M Phase |
| REAC:R-HSA-1640170 | 7.03245950423e-14 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Cell Cycle |
| GO:0032446 | 7.88755313016e-14 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | protein modification by small protein conjugation |
| GO:0010498 | 1.15306696261e-13 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | proteasomal protein catabolic process |
| REAC:R-HSA-1280218 | 1.2458872751e-13 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Adaptive Immune System |
| GO:1990234 | 2.40739445873e-13 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | transferase complex |
| GO:0044772 | 5.23198006552e-13 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | mitotic cell cycle phase transition |
| GO:0006511 | 7.66029319168e-13 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | ubiquitin-dependent protein catabolic process |
| GO:0019941 | 8.46293730911e-13 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | modification-dependent protein catabolic process |
| GO:0043632 | 1.10840796752e-12 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | modification-dependent macromolecule catabolic process |
| GO:0044770 | 1.13559126592e-12 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | cell cycle phase transition |
| GO:0007346 | 1.66241175447e-12 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | regulation of mitotic cell cycle |
| GO:0070647 | 1.71550586845e-12 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | protein modification by small protein conjugation or removal |
| GO:0051603 | 5.77631698237e-12 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | proteolysis involved in cellular protein catabolic process |
| GO:0010564 | 1.13713164383e-11 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | regulation of cell cycle process |
| GO:0044257 | 1.68376712356e-11 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | cellular protein catabolic process |
| GO:1903047 | 8.38270549174e-11 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | mitotic cell cycle process |
| GO:0030163 | 1.07683273897e-10 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | protein catabolic process |
| GO:1902494 | 2.68802717939e-10 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | catalytic complex |
| GO:0000278 | 5.28324209289e-10 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | mitotic cell cycle |
| GO:0051726 | 1.35838469363e-09 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | regulation of cell cycle |
| GO:0044265 | 3.25784119305e-09 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | cellular macromolecule catabolic process |
| GO:1901565 | 5.42398799849e-09 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | organonitrogen compound catabolic process |
| GO:0022402 | 1.42956258861e-08 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | cell cycle process |
| REAC:R-HSA-168256 | 1.93540216262e-08 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | Immune System |
| GO:0009057 | 2.22095329437e-08 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | macromolecule catabolic process |
| CORUM:5361 | 2.97527064635e-08 | 0.230769230769 | CDC27 CDC16 ANAPC7 | Cell division cycle complex (CDC27, CDC16, ANAPC7) |
| GO:0006508 | 5.6995756747e-08 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | proteolysis |
| GO:0007049 | 1.11621544597e-07 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | cell cycle |
| GO:1901575 | 2.42127073873e-06 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | organic substance catabolic process |
| GO:0044248 | 6.15568563865e-06 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | cellular catabolic process |
| GO:0007091 | 1.58707027926e-05 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | metaphase/anaphase transition of mitotic cell cycle |
| GO:0044784 | 1.77081858848e-05 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | metaphase/anaphase transition of cell cycle |
| GO:0010965 | 1.97116327235e-05 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | regulation of mitotic sister chromatid separation |
| GO:0051306 | 2.42606623267e-05 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | mitotic sister chromatid separation |
| GO:0009056 | 2.45126140758e-05 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | catabolic process |
| GO:1905818 | 2.96109919147e-05 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | regulation of chromosome separation |
| GO:0006464 | 3.29243213786e-05 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | cellular protein modification process |
| GO:0036211 | 3.29243213786e-05 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | protein modification process |
| GO:0033047 | 5.61780928741e-05 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | regulation of mitotic sister chromatid segregation |
| GO:0043412 | 6.97327366057e-05 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | macromolecule modification |
| GO:0033045 | 0.000123935985346 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | regulation of sister chromatid segregation |
| GO:0051304 | 0.000164659115557 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | chromosome separation |
| GO:0051983 | 0.000446018109171 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | regulation of chromosome segregation |
| GO:0044267 | 0.00095578453828 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | cellular protein metabolic process |
| GO:0044428 | 0.00261160858145 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | nuclear part |
| GO:0019538 | 0.00264493421084 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | protein metabolic process |
| GO:0007088 | 0.00308035018328 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | regulation of mitotic nuclear division |
| GO:0000070 | 0.00399143904334 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | mitotic sister chromatid segregation |
| GO:0051783 | 0.0041374055814 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | regulation of nuclear division |
| GO:0032991 | 0.00444280967359 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | protein-containing complex |
| GO:0005654 | 0.00474938988392 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | nucleoplasm |
| GO:0000819 | 0.00940607267604 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | sister chromatid segregation |
| KEGG:00000 | 0.0116697121743 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | KEGG root term |
| GO:1901564 | 0.0248751608987 | 1.0 | ANAPC2 CDC26 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC5 ANAPC1 CDC23 ANAPC16 FZR1 | organonitrogen compound metabolic process |
| HPA:032010_22 | 0.0256259459962 | 0.692307692308 | CDC16 CDC26 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 FZR1 | pancreas; exocrine glandular cells[Approved,Medium] |
| CORUM:0000000 | 0.0288016093364 | 0.692307692308 | ANAPC2 CDC16 CDC27 CDC23 ANAPC7 ANAPC10 ANAPC4 ANAPC1 ANAPC5 | CORUM root |
| GO:0098813 | 0.0290425217508 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | nuclear chromosome segregation |
| WP:000000 | 0.0298796988973 | 0.846153846154 | ANAPC2 CDC16 CDC27 ANAPC13 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | WIKIPATHWAYS |
| HPA:046010_21 | 0.0355796580789 | 0.692307692308 | CDC16 CDC26 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 FZR1 | smooth muscle; smooth muscle cells[Approved,Low] |
| GO:0031981 | 0.043521186735 | 0.923076923077 | ANAPC2 CDC26 CDC16 CDC27 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 ANAPC5 FZR1 | nuclear lumen |
| GO:0140014 | 0.0458415561205 | 0.384615384615 | CDC27 ANAPC5 ANAPC1 CDC23 ANAPC4 | mitotic nuclear division |
| HPA:055010_22 | 0.0493412484305 | 0.692307692308 | CDC16 CDC26 ANAPC16 ANAPC7 ANAPC10 ANAPC4 ANAPC1 CDC23 FZR1 | thyroid gland; glandular cells[Approved,Medium] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CDC27 | ANAPC1 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| CDC16 | CDC23 | 1.0 | 0.949 | hein_WMM bioplex (CDC16) bioplex_WMM boldt (CDC23) youn_WMM hein (CDC16,CDC23) Malo gupta_WMM fraction boldt_WMM |
| CDC27 | CDC16 | 1.0 | 0.949 | hein_WMM bioplex (CDC16) bioplex_WMM boldt youn_WMM hein (CDC16) Malo gupta_WMM fraction boldt_WMM |
| CDC16 | ANAPC1 | 1.0 | 0.949 | hein_WMM bioplex (CDC16) bioplex_WMM youn_WMM hein (CDC16) Malo gupta_WMM fraction boldt_WMM |
| ANAPC4 | CDC16 | 1.0 | 0.949 | hein_WMM bioplex (CDC16) bioplex_WMM youn_WMM hein (CDC16) Malo gupta_WMM fraction boldt_WMM |
| CDC27 | CDC23 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (CDC23) youn_WMM hein (CDC23) Malo gupta_WMM fraction boldt_WMM |
| ANAPC16 | CDC23 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC16,CDC23) Malo fraction boldt_WMM |
| CDC27 | ANAPC16 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC16) Malo fraction boldt_WMM |
| ANAPC5 | ANAPC1 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC5) Malo gupta_WMM fraction boldt_WMM |
| CDC16 | ANAPC5 | 1.0 | 0.949 | hein_WMM bioplex (CDC16) bioplex_WMM youn_WMM hein (ANAPC5,CDC16) Malo gupta_WMM fraction boldt_WMM |
| ANAPC16 | ANAPC1 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC16) Malo fraction boldt_WMM |
| ANAPC4 | ANAPC1 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| ANAPC2 | CDC16 | 1.0 | 0.949 | hein_WMM bioplex (CDC16) bioplex_WMM hein (ANAPC2,CDC16) Malo fraction boldt_WMM |
| CDC16 | CDC26 | 1.0 | 0.949 | hein_WMM bioplex (CDC16) bioplex_WMM youn_WMM hein (CDC16,CDC26) fraction |
| ANAPC13 | CDC16 | 1.0 | 0.949 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM hein (ANAPC13,CDC16) gupta_WMM fraction |
| CDC27 | ANAPC4 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| ANAPC16 | ANAPC5 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC16,ANAPC5) Malo fraction boldt_WMM |
| ANAPC4 | CDC23 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (CDC23) Malo gupta_WMM fraction boldt_WMM |
| ANAPC7 | CDC23 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (CDC23) youn_WMM hein (CDC23) Malo gupta_WMM fraction boldt_WMM |
| ANAPC4 | ANAPC16 | 0.999 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC16) Malo fraction boldt_WMM |
| ANAPC2 | ANAPC10 | 0.999 | 0.949 | hein_WMM bioplex_WMM hein (ANAPC2) Malo fraction boldt_WMM |
| ANAPC13 | CDC26 | 0.999 | 0.949 | hein_WMM bioplex (ANAPC13) bioplex_WMM hein (ANAPC13,CDC26) fraction |
| CDC16 | ANAPC7 | 0.999 | 0.948 | hein_WMM bioplex (CDC16) bioplex_WMM boldt youn_WMM hein (CDC16) gupta_WMM boldt_WMM |
| ANAPC4 | ANAPC5 | 0.999 | 0.946 | hein_WMM bioplex_WMM youn_WMM Malo fraction boldt_WMM |
| ANAPC2 | ANAPC4 | 0.998 | 0.939 | hein_WMM bioplex_WMM hein (ANAPC2) Malo fraction boldt_WMM |
| ANAPC13 | CDC23 | 0.998 | 0.939 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM hein (ANAPC13,CDC23) gupta_WMM fraction |
| CDC27 | ANAPC7 | 0.997 | 0.934 | hein_WMM bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| ANAPC16 | CDC16 | 0.996 | 0.927 | hein_WMM bioplex (CDC16) bioplex_WMM youn_WMM hein (ANAPC16,CDC16) boldt_WMM |
| ANAPC16 | ANAPC7 | 0.996 | 0.927 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC16) Malo fraction boldt_WMM |
| ANAPC2 | ANAPC13 | 0.994 | 0.921 | hein_WMM bioplex (ANAPC13) bioplex_WMM hein (ANAPC2) fraction |
| ANAPC13 | ANAPC5 | 0.993 | 0.918 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM hein (ANAPC13) gupta_WMM fraction |
| CDC16 | ANAPC10 | 0.992 | 0.912 | hein_WMM bioplex (CDC16) bioplex_WMM hein (CDC16) Malo fraction boldt_WMM |
| ANAPC10 | CDC23 | 0.991 | 0.91 | hein_WMM bioplex_WMM hein (CDC23) Malo fraction boldt_WMM |
| ANAPC4 | ANAPC7 | 0.989 | 0.902 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| ANAPC7 | ANAPC1 | 0.988 | 0.901 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| ANAPC4 | ANAPC10 | 0.988 | 0.902 | hein_WMM bioplex_WMM Malo fraction boldt_WMM |
| CDC27 | CDC26 | 0.987 | 0.902 | hein_WMM bioplex_WMM youn_WMM hein (CDC26) fraction |
| CDC27 | ANAPC13 | 0.987 | 0.901 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM hein (ANAPC13) gupta_WMM fraction |
| ANAPC13 | ANAPC1 | 0.984 | 0.899 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM hein (ANAPC13) gupta_WMM |
| ANAPC7 | ANAPC10 | 0.979 | 0.895 | hein_WMM bioplex_WMM Malo fraction boldt_WMM |
| ANAPC13 | ANAPC16 | 0.966 | 0.876 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM hein (ANAPC13,ANAPC16) |
| ANAPC13 | ANAPC7 | 0.965 | 0.875 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM hein (ANAPC13) gupta_WMM fraction |
| ANAPC13 | ANAPC4 | 0.965 | 0.875 | hein_WMM bioplex (ANAPC13) bioplex_WMM youn_WMM fraction |
| CDC27 | ANAPC10 | 0.959 | 0.865 | hein_WMM bioplex_WMM Malo fraction boldt_WMM |
| ANAPC16 | CDC26 | 0.92 | 0.844 | hein_WMM bioplex_WMM hein (ANAPC16,CDC26) fraction |
| CDC26 | ANAPC1 | 0.869 | 0.802 | hein_WMM bioplex_WMM youn_WMM hein (CDC26) fraction |
| ANAPC2 | FZR1 | 0.849 | 0.79 | hein_WMM bioplex (FZR1) bioplex_WMM hein (ANAPC2) |
| FZR1 | CDC16 | 0.797 | 0.764 | hein_WMM bioplex (FZR1) bioplex_WMM hein (CDC16) |
| ANAPC1 | CDC23 | 0.764 | 0.748 | hein_WMM bioplex_WMM youn_WMM hein (CDC23) gupta_WMM boldt_WMM |
| ANAPC5 | CDC23 | 0.733 | 0.738 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC5,CDC23) gupta_WMM boldt_WMM |
| FZR1 | CDC26 | 0.722 | 0.732 | hein_WMM bioplex (FZR1) bioplex_WMM hein (CDC26) |
| ANAPC2 | ANAPC1 | 0.649 | 0.687 | hein_WMM bioplex_WMM hein (ANAPC2) boldt_WMM |
| ANAPC4 | CDC26 | 0.601 | 0.671 | hein_WMM bioplex_WMM youn_WMM hein (CDC26) fraction |
| FZR1 | CDC23 | 0.579 | 0.661 | hein_WMM bioplex (FZR1) bioplex_WMM hein (CDC23) |
| CDC26 | ANAPC10 | 0.568 | 0.655 | hein_WMM bioplex_WMM hein (CDC26) fraction |
| ANAPC2 | CDC26 | 0.522 | 0.634 | hein_WMM bioplex_WMM hein (ANAPC2,CDC26) fraction |
| ANAPC2 | CDC23 | 0.481 | 0.612 | hein_WMM bioplex_WMM hein (ANAPC2,CDC23) boldt_WMM |
| ANAPC2 | CDC27 | 0.417 | 0.573 | hein_WMM bioplex_WMM hein (ANAPC2) boldt_WMM |
| ANAPC2 | ANAPC7 | 0.413 | 0.571 | hein_WMM bioplex_WMM hein (ANAPC2) boldt_WMM |
| ANAPC2 | ANAPC16 | 0.402 | 0.561 | hein_WMM bioplex_WMM hein (ANAPC16,ANAPC2) boldt_WMM |
| ANAPC2 | ANAPC5 | 0.355 | 0.54 | hein_WMM bioplex_WMM hein (ANAPC2,ANAPC5) boldt_WMM |
| CDC26 | CDC23 | 0.353 | 0.539 | hein_WMM bioplex_WMM youn_WMM hein (CDC23,CDC26) |
| ANAPC13 | ANAPC10 | 0.318 | 0.509 | hein_WMM bioplex (ANAPC13) bioplex_WMM fraction |
| ANAPC5 | CDC26 | 0.211 | 0.458 | hein_WMM bioplex_WMM youn_WMM hein (CDC26) |
| ANAPC7 | CDC26 | 0.16 | 0.418 | hein_WMM bioplex_WMM youn_WMM hein (CDC26) fraction |
| CDC27 | ANAPC5 | 0.111 | 0.38 | hein_WMM bioplex_WMM youn_WMM hein (ANAPC5) gupta_WMM boldt_WMM |
| CDC27 | FZR1 | 0.055 | 0.311 | hein_WMM bioplex (FZR1) bioplex_WMM |
| ANAPC16 | FZR1 | 0.043 | 0.269 | hein_WMM bioplex_WMM hein (ANAPC16) |
| ANAPC4 | FZR1 | 0.036 | 0.264 | hein_WMM bioplex (FZR1) bioplex_WMM |
| ANAPC13 | FZR1 | 0.033 | 0.251 | hein_WMM bioplex (ANAPC13) bioplex_WMM |
| ANAPC16 | ANAPC10 | 0.027 | 0.231 | hein_WMM bioplex_WMM hein (ANAPC16) boldt_WMM |
| FZR1 | ANAPC1 | 0.025 | 0.212 | hein_WMM bioplex (FZR1) bioplex_WMM |
| FZR1 | ANAPC10 | 0.022 | 0.205 | hein_WMM bioplex (FZR1) bioplex_WMM |
| ANAPC7 | ANAPC5 | 0.019 | 0.186 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| FZR1 | ANAPC5 | 0.014 | 0.138 | hein_WMM bioplex (FZR1) bioplex_WMM |
| ANAPC5 | ANAPC10 | 0.013 | 0.146 | hein_WMM bioplex_WMM WMM_only boldt_WMM |
| ANAPC10 | ANAPC1 | 0.012 | 0.146 | hein_WMM bioplex_WMM WMM_only boldt_WMM |
| FZR1 | ANAPC7 | 0.01 | 0.104 | hein_WMM bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_01190 has an average edge precision of 0.734 which is ranked 1247 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FZR1 | HuMAP2_00729 HuMAP2_01190 HuMAP2_02668 HuMAP2_03601 HuMAP2_04374 HuMAP2_04714 |
| CDC27 | HuMAP2_00729 HuMAP2_01027 HuMAP2_01190 HuMAP2_03601 |
| ANAPC2 | HuMAP2_00729 HuMAP2_01190 HuMAP2_03601 HuMAP2_06160 |
| ANAPC16 | HuMAP2_00729 HuMAP2_01190 HuMAP2_03601 |
| CDC26 | HuMAP2_00729 HuMAP2_01190 HuMAP2_03601 |
| ANAPC4 | HuMAP2_00729 HuMAP2_01027 HuMAP2_01190 HuMAP2_03601 |
| CDC16 | HuMAP2_00729 HuMAP2_01027 HuMAP2_01190 HuMAP2_03601 HuMAP2_04342 |
| ANAPC5 | HuMAP2_00729 HuMAP2_01190 HuMAP2_03601 |
| ANAPC10 | HuMAP2_00729 HuMAP2_01190 HuMAP2_03601 |
| CDC23 | HuMAP2_00729 HuMAP2_01027 HuMAP2_01190 HuMAP2_03601 |
| ANAPC1 | HuMAP2_00729 HuMAP2_01027 HuMAP2_01190 HuMAP2_03601 |
| ANAPC7 | HuMAP2_00729 HuMAP2_01190 HuMAP2_03601 |
| ANAPC13 | HuMAP2_00729 HuMAP2_01190 HuMAP2_03601 |