hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01212
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC25A31 | ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein) | UniProt NCBI |
| LRRCC1 | Leucine-rich repeat and coiled-coil domain-containing protein 1 (Centrosomal leucine-rich repeat and coiled-coil domain-containing protein) | UniProt NCBI |
| ATP2A1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase) | UniProt NCBI |
| ZNF684 | Zinc finger protein 684 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04022 | 0.0195308586359 | 0.5 | ATP2A1 SLC25A31 | cGMP-PKG signaling pathway |
| KEGG:04020 | 0.0248155779574 | 0.5 | ATP2A1 SLC25A31 | Calcium signaling pathway |
| CORUM:6514 | 0.0249595281251 | 0.25 | ATP2A1 | SLN-ATP2A1 complex |
| CORUM:6515 | 0.0249595281251 | 0.25 | ATP2A1 | SLN-PLN-SERCA1A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SLC25A31 | LRRCC1 | 0.653 | 0.69 | bioplex (LRRCC1) bioplex_WMM |
| ATP2A1 | LRRCC1 | 0.034 | 0.264 | bioplex (LRRCC1) bioplex_WMM |
| SLC25A31 | ZNF684 | 0.026 | 0.22 | bioplex (ZNF684) bioplex_WMM |
| ATP2A1 | SLC25A31 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01212 has an average edge precision of 0.294 which is ranked 4683 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC25A31 | HuMAP2_01212 HuMAP2_02963 HuMAP2_03527 HuMAP2_06173 |
| LRRCC1 | HuMAP2_01212 HuMAP2_03527 HuMAP2_06173 |
| ATP2A1 | HuMAP2_01212 |
| ZNF684 | HuMAP2_01212 HuMAP2_02963 |