hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01229
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IFT122 | Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140) | UniProt NCBI |
| TTC21B | Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) (Intraflagellar transport 139 homolog) | UniProt NCBI |
| WDR35 | WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog) | UniProt NCBI |
| WDR19 | WD repeat-containing protein 19 (Intraflagellar transport 144 homolog) | UniProt NCBI |
| IFT140 | Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) | UniProt NCBI |
| C11orf74 | Protein C11orf74 (Protein HEPIS) | UniProt NCBI |
| IFT43 | Intraflagellar transport protein 43 homolog | UniProt NCBI |
| TULP3 | Tubby-related protein 3 (Tubby-like protein 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6585 | 4.24766632997e-16 | 0.625 | WDR19 TTC21B WDR35 IFT122 IFT140 | Intraflagellar transport complex A |
| GO:0030991 | 6.46960706472e-16 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | intraciliary transport particle A |
| GO:0035721 | 4.267974068e-14 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | intraciliary retrograde transport |
| WP:WP4536 | 2.47611239596e-13 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | Genes related to primary cilium development (based on CRISPR) |
| REAC:R-HSA-5620924 | 5.87257017057e-12 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Intraflagellar transport |
| GO:0030990 | 1.63341960744e-11 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | intraciliary transport particle |
| WP:WP4532 | 3.73462369337e-11 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Intraflagellar transport proteins binding to dynein |
| GO:0035735 | 3.53407629573e-10 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | intraciliary transport involved in cilium assembly |
| GO:0061512 | 5.61118940136e-10 | 0.75 | TULP3 WDR19 IFT140 TTC21B WDR35 IFT122 | protein localization to cilium |
| GO:0097542 | 6.49641699236e-10 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | ciliary tip |
| REAC:R-HSA-5610787 | 7.33225119718e-10 | 0.75 | TULP3 WDR19 IFT140 TTC21B WDR35 IFT122 | Hedgehog 'off' state |
| HP:0000774 | 1.11585155779e-09 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Narrow chest |
| GO:0042073 | 1.46140232881e-09 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | intraciliary transport |
| HP:0005257 | 2.57388699937e-09 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Thoracic hypoplasia |
| REAC:R-HSA-5358351 | 3.3011925442e-09 | 0.75 | TULP3 WDR19 IFT140 TTC21B WDR35 IFT122 | Signaling by Hedgehog |
| GO:0098840 | 4.59885405516e-09 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | protein transport along microtubule |
| GO:0099118 | 4.59885405516e-09 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | microtubule-based protein transport |
| HP:0000773 | 1.71826397599e-08 | 0.625 | TTC21B IFT43 WDR35 IFT122 IFT140 | Short ribs |
| REAC:R-HSA-5617833 | 1.99852365652e-08 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Cilium Assembly |
| HP:0000944 | 3.05262078207e-08 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the metaphysis |
| HP:0009826 | 6.95742378784e-08 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Limb undergrowth |
| HP:0012622 | 1.43289705917e-07 | 0.625 | WDR19 TTC21B IFT140 IFT122 IFT43 | Chronic kidney disease |
| HP:0000772 | 1.51788687174e-07 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the ribs |
| HP:0006712 | 1.95347582113e-07 | 0.625 | TTC21B IFT43 WDR35 IFT122 IFT140 | Aplasia/Hypoplasia of the ribs |
| REAC:R-HSA-1852241 | 1.97065650475e-07 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Organelle biogenesis and maintenance |
| HP:0000968 | 2.37737319435e-07 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Ectodermal dysplasia |
| HP:0002983 | 3.26404487513e-07 | 0.625 | TTC21B WDR19 IFT43 WDR35 IFT140 | Micromelia |
| HP:0000691 | 3.44479946157e-07 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Microdontia |
| HP:0001156 | 4.78074865399e-07 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Brachydactyly |
| GO:0010970 | 5.1835889151e-07 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | transport along microtubule |
| HP:0001547 | 5.61092351416e-07 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the rib cage |
| HP:0000679 | 8.03155532972e-07 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Taurodontia |
| HP:0011071 | 8.03155532972e-07 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of permanent molar morphology |
| HP:0006479 | 8.03155532972e-07 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of the dental pulp |
| HP:0000083 | 8.31158103839e-07 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Renal insufficiency |
| GO:0044441 | 9.45716068527e-07 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | ciliary part |
| HP:0100259 | 9.50206180813e-07 | 0.625 | TTC21B WDR19 IFT43 WDR35 IFT140 | Postaxial polydactyly |
| GO:0099111 | 1.01372006916e-06 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | microtubule-based transport |
| HP:0011077 | 1.03534793477e-06 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of molar |
| HP:0006486 | 1.03534793477e-06 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of the dental root |
| HP:0011070 | 1.03534793477e-06 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of molar morphology |
| HP:0001159 | 1.10921036617e-06 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Syndactyly |
| HP:0001363 | 1.17672592956e-06 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Craniosynostosis |
| HP:0000090 | 1.31449288149e-06 | 0.5 | WDR19 TTC21B IFT140 IFT43 | Nephronophthisis |
| GO:0030705 | 1.40877955049e-06 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | cytoskeleton-dependent intracellular transport |
| HP:0004207 | 1.63717749252e-06 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal 5th finger morphology |
| HP:0006711 | 1.69180630958e-06 | 0.625 | TTC21B IFT43 WDR35 IFT122 IFT140 | Aplasia/Hypoplasia involving bones of the thorax |
| HP:0000268 | 1.82757316625e-06 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Dolichocephaly |
| HP:0008499 | 2.03765564003e-06 | 0.5 | WDR19 WDR35 IFT122 IFT43 | High hypermetropia |
| HP:0000766 | 2.35911740066e-06 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the sternum |
| HP:0010306 | 2.49454652724e-06 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Short thorax |
| HP:0000269 | 2.74980530968e-06 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Prominent occiput |
| HP:0100957 | 3.02413459246e-06 | 0.5 | WDR19 TTC21B IFT140 IFT43 | Abnormal renal medulla morphology |
| GO:0005929 | 4.1532167841e-06 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | cilium |
| HP:0009803 | 5.9848662374e-06 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Short phalanx of finger |
| HP:0011927 | 6.4603087016e-06 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Short digit |
| HP:0006482 | 7.14791501721e-06 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of dental morphology |
| HP:0000687 | 9.42303328574e-06 | 0.5 | IFT43 WDR35 IFT122 IFT140 | Widely spaced teeth |
| HP:0008905 | 9.42303328574e-06 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Rhizomelia |
| HP:0009767 | 1.11491375984e-05 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Aplasia/Hypoplasia of the phalanges of the hand |
| HP:0006494 | 1.33822984627e-05 | 0.625 | WDR19 TTC21B WDR35 IFT122 IFT140 | Aplasia/Hypoplasia involving bones of the feet |
| HP:0045060 | 1.46896983277e-05 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Aplasia/hypoplasia involving bones of the extremities |
| HP:0003774 | 1.50143856476e-05 | 0.5 | WDR19 TTC21B IFT140 IFT43 | Stage 5 chronic kidney disease |
| HP:0010442 | 1.51852489787e-05 | 0.625 | TTC21B WDR19 IFT43 WDR35 IFT140 | Polydactyly |
| GO:0031503 | 1.68892344458e-05 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | protein-containing complex localization |
| GO:0007018 | 1.82703489235e-05 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | microtubule-based movement |
| HP:0004442 | 1.90906692226e-05 | 0.375 | WDR19 IFT43 IFT122 | Sagittal craniosynostosis |
| HP:0011314 | 2.24938194814e-05 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of long bone morphology |
| HP:0009815 | 2.30431735766e-05 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Aplasia/hypoplasia of the extremities |
| HP:0001407 | 2.42910943475e-05 | 0.375 | WDR19 IFT122 TTC21B | Hepatic cysts |
| HP:0005918 | 2.65784522778e-05 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal finger phalanx morphology |
| HP:0012211 | 2.68923044444e-05 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal renal physiology |
| HP:0011329 | 2.8557490966e-05 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of cranial sutures |
| HP:0000601 | 2.99333731359e-05 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Hypotelorism |
| HP:0011217 | 3.49606707389e-05 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal shape of the occiput |
| HP:0008873 | 4.05941313091e-05 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Disproportionate short-limb short stature |
| HP:0001162 | 4.91289434064e-05 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Postaxial hand polydactyly |
| HP:0006493 | 5.09668179666e-05 | 0.625 | WDR19 TTC21B WDR35 IFT122 IFT140 | Aplasia/hypoplasia involving bones of the lower limbs |
| HP:0030799 | 6.45836076192e-05 | 0.375 | IFT140 IFT122 IFT43 | Scaphocephaly |
| HP:0001773 | 7.63095061024e-05 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Short foot |
| HP:0000232 | 7.95395466441e-05 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Everted lower lip vermilion |
| HP:0011218 | 8.2602313466e-05 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormal shape of the frontal region |
| HP:0002007 | 8.2602313466e-05 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Frontal bossing |
| HP:0001395 | 8.28706876709e-05 | 0.5 | WDR19 WDR35 IFT122 IFT140 | Hepatic fibrosis |
| HP:0003498 | 9.34915037097e-05 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Disproportionate short stature |
| HP:0012472 | 0.000105097914847 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Eclabion |
| HP:0008388 | 0.000113411935974 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal toenail morphology |
| HP:0410042 | 0.000114375619679 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal liver morphology |
| HP:0000235 | 0.000116233407208 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of the fontanelles or cranial sutures |
| HP:0000765 | 0.000121908150096 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the thorax |
| GO:0060271 | 0.000126788183612 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | cilium assembly |
| HP:0009882 | 0.000151668410454 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Short distal phalanx of finger |
| HP:0009835 | 0.000168243449261 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Aplasia/Hypoplasia of the distal phalanges of the hand |
| GO:0044782 | 0.000173033817276 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | cilium organization |
| HP:0006703 | 0.000192403275544 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Aplasia/Hypoplasia of the lungs |
| HP:0012210 | 0.000217210067382 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal renal morphology |
| HP:0000540 | 0.000240799653472 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Hypermetropia |
| HP:0006706 | 0.000269848756142 | 0.375 | WDR19 IFT122 TTC21B | Cystic liver disease |
| HP:0000668 | 0.000289056416216 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Hypodontia |
| HP:0011277 | 0.000322926244308 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the urinary system physiology |
| HP:0000682 | 0.000325009551192 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of dental enamel |
| HP:0001231 | 0.00036419879787 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal fingernail morphology |
| HP:0002652 | 0.000385064902112 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Skeletal dysplasia |
| HP:0001392 | 0.000389943214311 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the liver |
| GO:0120038 | 0.00039496102155 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | plasma membrane bounded cell projection part |
| GO:0044463 | 0.00039496102155 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | cell projection part |
| HP:3000050 | 0.000395826148734 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of odontoid tissue |
| HP:0009832 | 0.000406810175843 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal distal phalanx morphology of finger |
| HP:0001167 | 0.000464726281721 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of finger |
| HP:0001161 | 0.000465178107088 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Hand polydactyly |
| HP:0009115 | 0.000488645308224 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Aplasia/hypoplasia involving the skeleton |
| HP:0006101 | 0.000600397717211 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Finger syndactyly |
| HP:0002644 | 0.000612440632072 | 0.625 | TTC21B WDR19 IFT43 WDR35 IFT140 | Abnormality of pelvic girdle bone morphology |
| HP:0005692 | 0.000678052208658 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Joint hyperflexibility |
| HP:0000463 | 0.000744659087775 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Anteverted nares |
| HP:0009997 | 0.000799046684664 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Duplication of phalanx of hand |
| HP:0004275 | 0.000817560682485 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Duplication of hand bones |
| HP:0009142 | 0.000817560682485 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Duplication of bones involving the upper extremities |
| HP:0005288 | 0.000850916085232 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of the nares |
| HP:0001830 | 0.000939580488264 | 0.375 | WDR19 IFT140 TTC21B | Postaxial foot polydactyly |
| GO:0120031 | 0.000940537940189 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | plasma membrane bounded cell projection assembly |
| HP:0002012 | 0.00102689404716 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the abdominal organs |
| GO:0030031 | 0.00105961614518 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | cell projection assembly |
| HP:0000077 | 0.00107955525204 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the kidney |
| HP:0001780 | 0.00121857052867 | 0.625 | WDR19 TTC21B IFT140 IFT122 IFT43 | Abnormality of toe |
| HP:0010935 | 0.00127405028424 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the upper urinary tract |
| HP:0001760 | 0.00132893968786 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the foot |
| HP:0004322 | 0.00134497629625 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Short stature |
| HP:0000939 | 0.00142119754348 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Osteoporosis |
| HP:0005930 | 0.00144959409952 | 0.5 | WDR19 TTC21B IFT140 IFT122 | Abnormality of epiphysis morphology |
| HP:0000429 | 0.00148750524076 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of the nasal alae |
| HP:0011297 | 0.00148785708121 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal digit morphology |
| HP:0040069 | 0.0015767332569 | 0.625 | WDR19 TTC21B WDR35 IFT122 IFT140 | Abnormal lower limb bone morphology |
| HP:0000178 | 0.00179059130684 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of lower lip |
| HP:0000940 | 0.00185848223486 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal diaphysis morphology |
| HP:0009381 | 0.00189313692853 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Short finger |
| HP:0009804 | 0.00192827013949 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Reduced number of teeth |
| HP:0001155 | 0.00194950336279 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the hand |
| HP:0000002 | 0.00200488965669 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of body height |
| HP:0000692 | 0.00214936002123 | 0.5 | IFT43 WDR35 IFT122 IFT140 | Misalignment of teeth |
| HP:0000767 | 0.00230687429312 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Pectus excavatum |
| HP:0004209 | 0.00234755852173 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Clinodactyly of the 5th finger |
| HP:0010579 | 0.00237345021028 | 0.375 | WDR19 IFT140 TTC21B | Cone-shaped epiphysis |
| HP:0009179 | 0.00243052511994 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Deviation of the 5th finger |
| HP:0008070 | 0.00247281651547 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Sparse hair |
| HP:0006644 | 0.00248871678952 | 0.25 | WDR19 WDR35 | Thoracic dysplasia |
| HP:0002213 | 0.00249350467565 | 0.375 | WDR35 IFT122 IFT43 | Fine hair |
| HP:0001382 | 0.00260297760598 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Joint hypermobility |
| HP:0010322 | 0.00261751913606 | 0.375 | WDR19 IFT140 TTC21B | Abnormality of the 5th toe |
| HP:0006483 | 0.00283114453605 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal number of teeth |
| HP:0011357 | 0.00302412121558 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of hair density |
| HP:0011061 | 0.00302412121558 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of dental structure |
| HP:0002817 | 0.00314823086166 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the upper limb |
| HP:0002813 | 0.00334844254703 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of limb bone morphology |
| HP:0040068 | 0.00334844254703 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of limb bone |
| HP:0040019 | 0.00338513780385 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Finger clinodactyly |
| HP:0006265 | 0.0034392099436 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Aplasia/Hypoplasia of fingers |
| HP:0002814 | 0.00374277991825 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the lower limb |
| HP:0002648 | 0.00386113237196 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of calvarial morphology |
| HP:0009122 | 0.00401823706933 | 0.625 | TTC21B IFT43 WDR35 IFT122 IFT140 | Aplasia/hypoplasia affecting bones of the axial skeleton |
| HP:0000545 | 0.00413934167929 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Myopia |
| HP:0000973 | 0.00426097292117 | 0.375 | WDR19 WDR35 IFT43 | Cutis laxa |
| HP:0011844 | 0.00516213833898 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal appendicular skeleton morphology |
| HP:0005922 | 0.00545735168842 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal hand morphology |
| HP:0000164 | 0.00588478974331 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of the dentition |
| HP:0001799 | 0.0059681081945 | 0.25 | IFT43 IFT122 | Short nail |
| GO:0120025 | 0.00603881254865 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | plasma membrane bounded cell projection |
| HP:0001510 | 0.00636361355162 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Growth delay |
| GO:0042995 | 0.00641275397842 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | cell projection |
| HP:0010938 | 0.0066554649482 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of the external nose |
| HP:0000112 | 0.0069443613846 | 0.375 | WDR19 IFT140 TTC21B | Nephropathy |
| GO:0007017 | 0.0070136898898 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | microtubule-based process |
| WP:WP4352 | 0.00764439931257 | 0.375 | IFT140 IFT122 IFT43 | Ciliary landscape |
| HP:0000290 | 0.007876910085 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of the forehead |
| HP:0000293 | 0.00795116344928 | 0.375 | WDR19 WDR35 IFT122 | Full cheeks |
| HP:0002683 | 0.00804124668873 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormality of the calvaria |
| HP:0004097 | 0.008560867729 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Deviation of finger |
| HP:0005105 | 0.0087258661226 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormal nasal morphology |
| HP:0002088 | 0.00884430713945 | 0.625 | TTC21B WDR19 IFT43 WDR35 IFT140 | Abnormal lung morphology |
| HP:0000889 | 0.00905007554403 | 0.375 | WDR19 IFT140 TTC21B | Abnormality of the clavicle |
| HP:0001829 | 0.00963529148538 | 0.375 | WDR19 IFT140 TTC21B | Foot polydactyly |
| HP:0009484 | 0.00979935799313 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Deviation of the hand or of fingers of the hand |
| HP:0001597 | 0.0100380518138 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of the nail |
| HP:0000079 | 0.0107352206567 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of the urinary system |
| HP:0009136 | 0.0108796714446 | 0.375 | WDR19 IFT140 TTC21B | Duplication involving bones of the feet |
| HP:0000639 | 0.0109182372354 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Nystagmus |
| GO:0070925 | 0.0111731156143 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | organelle assembly |
| HP:0012547 | 0.0116393290133 | 0.625 | WDR19 IFT43 WDR35 IFT122 IFT140 | Abnormal involuntary eye movements |
| HP:0030084 | 0.0131031690513 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Clinodactyly |
| HP:0004349 | 0.0135486926517 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Reduced bone mineral density |
| HP:0008067 | 0.0136777576076 | 0.375 | WDR19 WDR35 IFT43 | Abnormally lax or hyperextensible skin |
| HP:0005927 | 0.0143160113104 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Aplasia/hypoplasia involving bones of the hand |
| HP:0000506 | 0.0152391607346 | 0.375 | WDR35 IFT122 IFT43 | Telecanthus |
| HP:0000286 | 0.0162884350978 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Epicanthus |
| HP:0000539 | 0.0182666998945 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of refraction |
| HP:0012252 | 0.018860152253 | 0.625 | TTC21B WDR19 IFT43 WDR35 IFT140 | Abnormal respiratory system morphology |
| HP:0006496 | 0.0198130668967 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Aplasia/hypoplasia involving bones of the upper limbs |
| HP:0009836 | 0.0198563136463 | 0.25 | WDR19 IFT122 | Broad distal phalanx of finger |
| REAC:R-HSA-162582 | 0.020478873125 | 0.75 | TULP3 WDR19 IFT140 TTC21B WDR35 IFT122 | Signal Transduction |
| HP:0040064 | 0.0222539662917 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormality of limbs |
| HP:0001970 | 0.0224977761754 | 0.25 | WDR19 IFT122 | Tubulointerstitial nephritis |
| GO:0033365 | 0.0232541780893 | 0.75 | TULP3 WDR19 IFT140 TTC21B WDR35 IFT122 | protein localization to organelle |
| HP:0004348 | 0.0234178973438 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormality of bone mineral density |
| HP:0010719 | 0.0283203909549 | 0.375 | WDR35 IFT122 IFT43 | Abnormality of hair texture |
| HP:0002093 | 0.0287750086045 | 0.5 | WDR19 TTC21B WDR35 IFT140 | Respiratory insufficiency |
| HP:0010647 | 0.0348458133379 | 0.375 | WDR19 WDR35 IFT43 | Abnormal elasticity of skin |
| HP:0012372 | 0.0360693442595 | 0.75 | IFT140 IFT122 WDR19 WDR35 TTC21B IFT43 | Abnormal eye morphology |
| HP:0003026 | 0.0377100700127 | 0.375 | TTC21B WDR35 IFT122 | Short long bone |
| HP:0001388 | 0.0377100700127 | 0.375 | WDR35 IFT122 IFT43 | Joint laxity |
| GO:0120160 | 0.0378589948753 | 0.25 | C11orf74 TULP3 | intraciliary transport particle A binding |
| GO:0034613 | 0.0398294539613 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | cellular protein localization |
| GO:0070727 | 0.0414994148133 | 0.875 | IFT140 TULP3 WDR19 WDR35 TTC21B IFT43 IFT122 | cellular macromolecule localization |
| HP:0004426 | 0.0422901516914 | 0.375 | WDR19 WDR35 IFT122 | Abnormality of the cheek |
| HP:0000546 | 0.0430873277361 | 0.375 | WDR19 IFT140 TTC21B | Retinal degeneration |
| HP:0011849 | 0.0468310960959 | 0.5 | WDR19 WDR35 IFT122 IFT43 | Abnormal bone ossification |
| HP:0001770 | 0.0480785191905 | 0.375 | WDR19 IFT140 TTC21B | Toe syndactyly |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR35 | C11orf74 | 1.0 | 0.949 | bioplex (C11orf74) bioplex_WMM boldt boldt_WMM |
| WDR35 | IFT43 | 0.999 | 0.949 | bioplex (IFT43) bioplex_WMM boldt (IFT43,WDR35) boldt_WMM |
| TTC21B | IFT43 | 0.995 | 0.924 | bioplex (IFT43) bioplex_WMM boldt (IFT43) boldt_WMM |
| WDR19 | IFT43 | 0.988 | 0.902 | bioplex (IFT43) bioplex_WMM boldt (IFT43,WDR19) boldt_WMM |
| IFT140 | IFT43 | 0.983 | 0.898 | bioplex (IFT43) bioplex_WMM boldt (IFT140,IFT43) boldt_WMM |
| TTC21B | TULP3 | 0.978 | 0.894 | bioplex (TULP3) bioplex_WMM boldt (TULP3) boldt_WMM |
| IFT43 | IFT122 | 0.951 | 0.858 | bioplex (IFT122,IFT43) bioplex_WMM boldt (IFT122,IFT43) boldt_WMM |
| C11orf74 | IFT43 | 0.945 | 0.856 | bioplex (C11orf74,IFT43) bioplex_WMM boldt boldt_WMM |
| C11orf74 | IFT140 | 0.863 | 0.8 | bioplex (C11orf74) bioplex_WMM boldt boldt_WMM |
| WDR19 | IFT122 | 0.796 | 0.762 | bioplex (IFT122) bioplex_WMM boldt (IFT122,WDR19) boldt_WMM |
| WDR19 | C11orf74 | 0.789 | 0.758 | bioplex (C11orf74) bioplex_WMM boldt boldt_WMM |
| C11orf74 | IFT122 | 0.782 | 0.756 | bioplex (C11orf74) bioplex_WMM boldt (IFT122) boldt_WMM |
| TULP3 | WDR35 | 0.768 | 0.75 | bioplex (TULP3) bioplex_WMM boldt (TULP3) boldt_WMM |
| IFT140 | IFT122 | 0.72 | 0.732 | bioplex (IFT122) bioplex_WMM boldt (IFT122,IFT140) boldt_WMM |
| WDR35 | IFT122 | 0.656 | 0.695 | bioplex (IFT122) bioplex_WMM boldt (IFT122,WDR35) boldt_WMM |
| TULP3 | IFT122 | 0.654 | 0.692 | bioplex (TULP3) bioplex_WMM boldt (TULP3) boldt_WMM |
| TULP3 | WDR19 | 0.62 | 0.675 | bioplex (TULP3) bioplex_WMM boldt (TULP3,WDR19) boldt_WMM |
| TULP3 | IFT140 | 0.596 | 0.667 | bioplex (TULP3) bioplex_WMM boldt (TULP3) boldt_WMM |
| WDR35 | WDR19 | 0.069 | 0.349 | bioplex_WMM boldt (WDR19,WDR35) boldt_WMM |
| TULP3 | IFT43 | 0.019 | 0.184 | bioplex (IFT43,TULP3) bioplex_WMM boldt (TULP3) boldt_WMM |
| TTC21B | IFT140 | 0.017 | 0.173 | bioplex_WMM boldt (IFT140) boldt_WMM |
| TTC21B | WDR35 | 0.017 | 0.171 | bioplex_WMM boldt (WDR35) boldt_WMM |
| TTC21B | IFT122 | 0.017 | 0.168 | bioplex_WMM boldt (IFT122) boldt_WMM |
| TTC21B | WDR19 | 0.016 | 0.164 | bioplex_WMM boldt (WDR19) boldt_WMM |
| WDR19 | IFT140 | 0.011 | 0.141 | bioplex_WMM boldt (IFT140,WDR19) fraction boldt_WMM |
| TULP3 | C11orf74 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| TTC21B | C11orf74 | 0.008 | 0.024 | bioplex_WMM boldt boldt_WMM |
| WDR35 | IFT140 | 0.0 | 0.001 | bioplex_WMM boldt (IFT140,WDR35) fraction boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_01229 has an average edge precision of 0.571 which is ranked 2081 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IFT122 | HuMAP2_01229 HuMAP2_03603 |
| TTC21B | HuMAP2_00920 HuMAP2_01229 HuMAP2_05938 |
| WDR35 | HuMAP2_01229 HuMAP2_03603 |
| WDR19 | HuMAP2_01229 HuMAP2_03603 |
| IFT140 | HuMAP2_01229 HuMAP2_01474 HuMAP2_03603 |
| C11orf74 | HuMAP2_01229 HuMAP2_03603 |
| IFT43 | HuMAP2_01229 HuMAP2_03603 HuMAP2_05938 |
| TULP3 | HuMAP2_00920 HuMAP2_01229 HuMAP2_04929 |