hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01232
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PKM | Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58) | UniProt NCBI |
| FSCN1 | Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) | UniProt NCBI |
| MVB12B | Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B) | UniProt NCBI |
| CPOX | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3) | UniProt NCBI |
| CRIP2 | Cysteine-rich protein 2 (CRP-2) (Protein ESP1) | UniProt NCBI |
| SPR | Sepiapterin reductase (SPR) (EC 1.1.1.153) | UniProt NCBI |
| CARHSP1 | Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-3909 | 0.000733581175223 | 0.428571428571 | PKM MVB12B CARHSP1 | hsa-miR-3909 |
| CORUM:7403 | 0.0499886427319 | 0.142857142857 | PKM | SREBP-1a-PKM2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CPOX | FSCN1 | 0.47 | 0.605 | bioplex_WMM fraction |
| CPOX | PKM | 0.1 | 0.361 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| SPR | FSCN1 | 0.082 | 0.351 | bioplex_WMM fraction |
| FSCN1 | PKM | 0.055 | 0.311 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| FSCN1 | CARHSP1 | 0.055 | 0.306 | bioplex_WMM fraction |
| SPR | CRIP2 | 0.029 | 0.231 | fraction |
| PKM | MVB12B | 0.023 | 0.208 | bioplex (MVB12B) bioplex_WMM fraction |
| SPR | PKM | 0.02 | 0.184 | bioplex_WMM fraction treiber_WMM |
| CPOX | MVB12B | 0.007 | 0.001 | bioplex_WMM WMM_only |
| FSCN1 | CRIP2 | 0.004 | 0.01 | fraction |
| CPOX | CARHSP1 | 0.004 | 0.01 | bioplex_WMM fraction |
| SPR | CPOX | 0.003 | 0.015 | bioplex_WMM fraction |
| PKM | CARHSP1 | 0.0 | 0.011 | bioplex_WMM gupta_WMM fraction |
| CARHSP1 | CRIP2 | 0.0 | 0.017 | fraction |
| SPR | CARHSP1 | 0.0 | 0.001 | bioplex_WMM fraction |
Images
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Complex HuMAP2_01232 has an average edge precision of 0.175 which is ranked 6480 out of all 6965 complexes.
Related Complexes