hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01251
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CSNK2B | Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a) | UniProt NCBI |
| CSNK2A1 | Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5225 | 1.67592346237e-06 | 1.0 | CSNK2B CSNK2A1 | Casein kinase II (beta-dimer, alpha-dimer) |
| CORUM:2720 | 5.02777038712e-06 | 1.0 | CSNK2B CSNK2A1 | Casein kinase II (beta-dimer, alpha, alpha') |
| CORUM:5224 | 5.02777038712e-06 | 1.0 | CSNK2B CSNK2A1 | Casein kinase II (beta-dimer, alpha, alpha') |
| CORUM:2719 | 1.00555407742e-05 | 1.0 | CSNK2B CSNK2A1 | Casein kinase II-HMG1 complex |
| CORUM:938 | 1.67592346237e-05 | 1.0 | CSNK2B CSNK2A1 | FACT complex, UV-activated |
| REAC:R-HSA-201688 | 4.69258569465e-05 | 1.0 | CSNK2B CSNK2A1 | WNT mediated activation of DVL |
| REAC:R-HSA-8934903 | 6.03332446455e-05 | 1.0 | CSNK2B CSNK2A1 | Receptor Mediated Mitophagy |
| REAC:R-HSA-2514853 | 9.21757904306e-05 | 1.0 | CSNK2B CSNK2A1 | Condensation of Prometaphase Chromosomes |
| KEGG:04137 | 0.00027589225596 | 1.0 | CSNK2B CSNK2A1 | Mitophagy - animal |
| REAC:R-HSA-445144 | 0.000318425457851 | 1.0 | CSNK2B CSNK2A1 | Signal transduction by L1 |
| KEGG:04520 | 0.000342275638542 | 1.0 | CSNK2B CSNK2A1 | Adherens junction |
| KEGG:03008 | 0.000426896214141 | 1.0 | CSNK2B CSNK2A1 | Ribosome biogenesis in eukaryotes |
| KEGG:04064 | 0.000449510333482 | 1.0 | CSNK2B CSNK2A1 | NF-kappa B signaling pathway |
| KEGG:05235 | 0.000461036239468 | 1.0 | CSNK2B CSNK2A1 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
| REAC:R-HSA-5205647 | 0.000462554875615 | 1.0 | CSNK2B CSNK2A1 | Mitophagy |
| REAC:R-HSA-1483191 | 0.000544675125272 | 1.0 | CSNK2B CSNK2A1 | Synthesis of PC |
| REAC:R-HSA-8939243 | 0.0010558317813 | 1.0 | CSNK2B CSNK2A1 | RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known |
| WP:WP4336 | 0.00111886173915 | 1.0 | CSNK2B CSNK2A1 | ncRNAs involved in Wnt signaling in hepatocellular carcinoma |
| KEGG:05162 | 0.00118585523873 | 1.0 | CSNK2B CSNK2A1 | Measles |
| REAC:R-HSA-6814122 | 0.00124185928562 | 1.0 | CSNK2B CSNK2A1 | Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding |
| GO:0005956 | 0.00135247023414 | 1.0 | CSNK2B CSNK2A1 | protein kinase CK2 complex |
| WP:WP4258 | 0.00139382676196 | 1.0 | CSNK2B CSNK2A1 | LncRNA involvement in canonical Wnt signaling and colorectal cancer |
| KEGG:04310 | 0.00156562654612 | 1.0 | CSNK2B CSNK2A1 | Wnt signaling pathway |
| WP:WP428 | 0.00211290873217 | 1.0 | CSNK2B CSNK2A1 | Wnt Signaling |
| WP:WP4262 | 0.00357342755251 | 1.0 | CSNK2B CSNK2A1 | Breast cancer pathway |
| REAC:R-HSA-8948751 | 0.00381775364729 | 1.0 | CSNK2B CSNK2A1 | Regulation of PTEN stability and activity |
| REAC:R-HSA-1632852 | 0.00626962967274 | 1.0 | CSNK2B CSNK2A1 | Macroautophagy |
| REAC:R-HSA-390466 | 0.00671207346681 | 1.0 | CSNK2B CSNK2A1 | Chaperonin-mediated protein folding |
| REAC:R-HSA-6804756 | 0.00686290657842 | 1.0 | CSNK2B CSNK2A1 | Regulation of TP53 Activity through Phosphorylation |
| REAC:R-HSA-391251 | 0.00764221098843 | 1.0 | CSNK2B CSNK2A1 | Protein folding |
| REAC:R-HSA-9612973 | 0.00880362594785 | 1.0 | CSNK2B CSNK2A1 | Autophagy |
| REAC:R-HSA-1483206 | 0.00950416195513 | 1.0 | CSNK2B CSNK2A1 | Glycerophospholipid biosynthesis |
| REAC:R-HSA-373760 | 0.0102315127378 | 1.0 | CSNK2B CSNK2A1 | L1CAM interactions |
| REAC:R-HSA-6807070 | 0.0151587277172 | 1.0 | CSNK2B CSNK2A1 | PTEN Regulation |
| REAC:R-HSA-5633007 | 0.0205233587202 | 1.0 | CSNK2B CSNK2A1 | Regulation of TP53 Activity |
| REAC:R-HSA-1483257 | 0.0282158474125 | 1.0 | CSNK2B CSNK2A1 | Phospholipid metabolism |
| REAC:R-HSA-68877 | 0.0304096312248 | 1.0 | CSNK2B CSNK2A1 | Mitotic Prometaphase |
| REAC:R-HSA-8878171 | 0.0400059689703 | 1.0 | CSNK2B CSNK2A1 | Transcriptional regulation by RUNX1 |
| REAC:R-HSA-201681 | 0.0411120784555 | 1.0 | CSNK2B CSNK2A1 | TCF dependent signaling in response to WNT |
| REAC:R-HSA-1257604 | 0.0422332712518 | 1.0 | CSNK2B CSNK2A1 | PIP3 activates AKT signaling |
| CORUM:5223 | 0.0499173803268 | 0.5 | CSNK2B | Casein kinase II (beta-dimer, alpha'-dimer) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CSNK2A1 | CSNK2B | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_01251 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CSNK2B | HuMAP2_01251 HuMAP2_05042 HuMAP2_05669 HuMAP2_06657 HuMAP2_06828 |
| CSNK2A1 | HuMAP2_01251 HuMAP2_05042 HuMAP2_05669 HuMAP2_06657 HuMAP2_06828 |