hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01257
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CNOT2 | CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) | UniProt NCBI |
| CNOT1 | CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1) | UniProt NCBI |
| CNOT6 | CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase) | UniProt NCBI |
| CNOT3 | CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2) | UniProt NCBI |
| CNOT8 | CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b) | UniProt NCBI |
| CNOT9 | CCR4-NOT transcription complex subunit 9 (Cell differentiation protein RQCD1 homolog) (Rcd-1) | UniProt NCBI |
| TNKS1BP1 | 182 kDa tankyrase-1-binding protein | UniProt NCBI |
| CNOT11 | CCR4-NOT transcription complex subunit 11 | UniProt NCBI |
| CNOT7 | CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a) | UniProt NCBI |
| CNOT6L | CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) (Carbon catabolite repressor protein 4 homolog B) | UniProt NCBI |
| CNOT10 | CCR4-NOT transcription complex subunit 10 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6804115 | 1.8444887895e-31 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain |
| GO:0030014 | 1.09367335283e-30 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | CCR4-NOT complex |
| REAC:R-HSA-429947 | 4.89498947982e-30 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | Deadenylation of mRNA |
| CORUM:7215 | 3.75317718203e-29 | 0.818181818182 | CNOT6 CNOT3 TNKS1BP1 CNOT9 CNOT11 CNOT8 CNOT1 CNOT10 CNOT2 | CCR4-NOT-CNOT8-CNOT6 complex |
| CORUM:7214 | 3.75317718203e-29 | 0.818181818182 | CNOT6L CNOT7 CNOT3 TNKS1BP1 CNOT9 CNOT11 CNOT1 CNOT10 CNOT2 | CCR4-NOT-CNOT7-CNOT6L complex |
| CORUM:7192 | 3.75317718203e-29 | 0.818181818182 | CNOT6 CNOT3 TNKS1BP1 CNOT9 CNOT11 CNOT1 CNOT10 CNOT2 CNOT7 | CCR4-NOT-CNOT7-CNOT6 complex |
| CORUM:6765 | 3.75317718203e-29 | 0.818181818182 | CNOT6L CNOT6 CNOT3 CNOT11 CNOT9 CNOT1 CNOT10 CNOT2 CNOT7 | CCR4-NOT complex |
| CORUM:7216 | 3.75317718203e-29 | 0.818181818182 | CNOT6L CNOT11 CNOT3 TNKS1BP1 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | CCR4-NOT-CNOT8-CNOT6L complex |
| REAC:R-HSA-6791312 | 2.48134042481e-26 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | TP53 Regulates Transcription of Cell Cycle Genes |
| GO:0000289 | 3.23055484521e-26 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | nuclear-transcribed mRNA poly(A) tail shortening |
| REAC:R-HSA-429914 | 1.63520163619e-25 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | Deadenylation-dependent mRNA decay |
| GO:0006977 | 2.39673839819e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest |
| GO:1902400 | 2.99592299774e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | intracellular signal transduction involved in G1 DNA damage checkpoint |
| GO:0072431 | 2.99592299774e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction involved in mitotic G1 DNA damage checkpoint |
| GO:1902403 | 3.72825973052e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction involved in mitotic DNA integrity checkpoint |
| GO:1902402 | 3.72825973052e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction involved in mitotic DNA damage checkpoint |
| GO:0072413 | 3.72825973052e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction involved in mitotic cell cycle checkpoint |
| GO:0044819 | 8.58063175486e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic G1/S transition checkpoint |
| GO:0031571 | 8.58063175486e-23 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic G1 DNA damage checkpoint |
| GO:0044783 | 1.04683707409e-22 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | G1 DNA damage checkpoint |
| GO:0072401 | 4.56651292598e-22 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction involved in DNA integrity checkpoint |
| GO:0072422 | 4.56651292598e-22 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction involved in DNA damage checkpoint |
| GO:0000288 | 5.41789669184e-22 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| GO:0072395 | 5.41789669184e-22 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction involved in cell cycle checkpoint |
| GO:0071158 | 8.90987579708e-22 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | positive regulation of cell cycle arrest |
| GO:2000134 | 7.0120429639e-21 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of G1/S transition of mitotic cell cycle |
| GO:0044773 | 8.01376338731e-21 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic DNA damage checkpoint |
| GO:1902807 | 8.01376338731e-21 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of cell cycle G1/S phase transition |
| GO:0030330 | 1.72870309162e-20 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | DNA damage response, signal transduction by p53 class mediator |
| GO:0071156 | 1.72870309162e-20 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of cell cycle arrest |
| GO:0044774 | 2.4905216321e-20 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic DNA integrity checkpoint |
| GO:0042770 | 2.17241096847e-19 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction in response to DNA damage |
| GO:2000045 | 2.63975379191e-19 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of G1/S transition of mitotic cell cycle |
| GO:0000077 | 6.09292376255e-19 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | DNA damage checkpoint |
| GO:1902806 | 7.27662238271e-19 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of cell cycle G1/S phase transition |
| GO:0031570 | 1.6974987684e-18 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | DNA integrity checkpoint |
| GO:0007093 | 3.19872643965e-18 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic cell cycle checkpoint |
| KEGG:03018 | 3.53108304864e-18 | 0.818181818182 | CNOT6L CNOT6 CNOT3 CNOT2 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | RNA degradation |
| GO:0007050 | 5.12554000171e-17 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cell cycle arrest |
| GO:0000075 | 5.12554000171e-17 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cell cycle checkpoint |
| GO:0000956 | 8.18680955365e-17 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | nuclear-transcribed mRNA catabolic process |
| GO:1901991 | 8.66838658622e-17 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of mitotic cell cycle phase transition |
| GO:0000082 | 1.02717430415e-16 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | G1/S transition of mitotic cell cycle |
| GO:1901988 | 1.77592946656e-16 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of cell cycle phase transition |
| GO:0090068 | 1.87311963637e-16 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | positive regulation of cell cycle process |
| GO:0044843 | 1.97512120073e-16 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cell cycle G1/S phase transition |
| REAC:R-HSA-3700989 | 2.12591899223e-16 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | Transcriptional Regulation by TP53 |
| GO:0072331 | 4.92237132602e-16 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction by p53 class mediator |
| GO:0030015 | 1.52515442273e-15 | 0.545454545455 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT2 | CCR4-NOT core complex |
| GO:0045787 | 2.50273847587e-15 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | positive regulation of cell cycle |
| GO:0045930 | 2.60985957795e-15 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of mitotic cell cycle |
| GO:0010948 | 5.4065006756e-15 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of cell cycle process |
| GO:0006402 | 3.38650312183e-14 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mRNA catabolic process |
| GO:1901990 | 4.84709530229e-14 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of mitotic cell cycle phase transition |
| GO:0006401 | 8.77124557273e-14 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | RNA catabolic process |
| GO:1901987 | 1.05099075549e-13 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of cell cycle phase transition |
| REAC:R-HSA-8953854 | 2.28772838784e-13 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | Metabolism of RNA |
| GO:0034655 | 1.05912634826e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | nucleobase-containing compound catabolic process |
| GO:0044772 | 1.34597228896e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic cell cycle phase transition |
| GO:0004535 | 1.40681009827e-12 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | poly(A)-specific ribonuclease activity |
| GO:0045786 | 2.34405080199e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of cell cycle |
| GO:0046700 | 2.39743498174e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | heterocycle catabolic process |
| GO:0044270 | 2.45192214042e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cellular nitrogen compound catabolic process |
| GO:0044770 | 2.74163087954e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cell cycle phase transition |
| GO:0019439 | 3.19959775399e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | aromatic compound catabolic process |
| GO:0007346 | 3.89034131867e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of mitotic cell cycle |
| GO:1901361 | 4.91741829028e-12 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | organic cyclic compound catabolic process |
| GO:0010564 | 2.27534200838e-11 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of cell cycle process |
| REAC:R-HSA-212436 | 3.7675671311e-11 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | Generic Transcription Pathway |
| REAC:R-HSA-73857 | 1.255616691e-10 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | RNA Polymerase II Transcription |
| GO:0006974 | 1.38361431651e-10 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cellular response to DNA damage stimulus |
| GO:0016071 | 1.40529488272e-10 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mRNA metabolic process |
| GO:1903047 | 1.42728384959e-10 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic cell cycle process |
| REAC:R-HSA-74160 | 4.19314911511e-10 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | Gene expression (Transcription) |
| GO:0000278 | 7.76202366797e-10 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | mitotic cell cycle |
| GO:0051726 | 1.85128316411e-09 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of cell cycle |
| GO:0000175 | 2.4549713949e-09 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | 3'-5'-exoribonuclease activity |
| GO:0016896 | 3.51412536992e-09 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | exoribonuclease activity, producing 5'-phosphomonoesters |
| GO:0044265 | 4.14297854427e-09 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cellular macromolecule catabolic process |
| GO:0004532 | 4.92891182764e-09 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | exoribonuclease activity |
| GO:0017148 | 9.92154610372e-09 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | negative regulation of translation |
| GO:0022402 | 1.61852963497e-08 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cell cycle process |
| CORUM:6394 | 2.02774899104e-08 | 0.272727272727 | CNOT3 CNOT2 CNOT1 | CNOT1-CNOT2-CNOT3 complex |
| GO:0034249 | 2.18774399626e-08 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | negative regulation of cellular amide metabolic process |
| GO:0009057 | 2.42951320397e-08 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | macromolecule catabolic process |
| GO:0016796 | 3.45425357653e-08 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0010606 | 4.0237537548e-08 | 0.363636363636 | CNOT6L CNOT6 CNOT1 CNOT2 | positive regulation of cytoplasmic mRNA processing body assembly |
| GO:0008408 | 4.35935913079e-08 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | 3'-5' exonuclease activity |
| GO:0007049 | 1.07746331475e-07 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cell cycle |
| GO:0000932 | 1.23851013548e-07 | 0.545454545455 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT2 | P-body |
| GO:0010629 | 2.72557524123e-07 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of gene expression |
| GO:0010603 | 2.81450928027e-07 | 0.363636363636 | CNOT6L CNOT6 CNOT1 CNOT2 | regulation of cytoplasmic mRNA processing body assembly |
| GO:0004527 | 3.26763199327e-07 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | exonuclease activity |
| GO:0033554 | 8.29366945024e-07 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cellular response to stress |
| GO:1901575 | 1.85056557191e-06 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | organic substance catabolic process |
| GO:0004540 | 1.88061112316e-06 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | ribonuclease activity |
| GO:0044248 | 4.3898747975e-06 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cellular catabolic process |
| GO:0006417 | 5.53340495254e-06 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | regulation of translation |
| CORUM:0000000 | 6.27334655689e-06 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | CORUM root |
| GO:0010605 | 8.29335075424e-06 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of macromolecule metabolic process |
| GO:0010608 | 9.97288569569e-06 | 0.727272727273 | CNOT6 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 CNOT7 | posttranscriptional regulation of gene expression |
| GO:0035556 | 1.12486268001e-05 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | intracellular signal transduction |
| GO:0033962 | 1.45859703988e-05 | 0.363636363636 | CNOT6L CNOT6 CNOT1 CNOT2 | cytoplasmic mRNA processing body assembly |
| GO:0009056 | 1.58011795645e-05 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | catabolic process |
| WP:WP4352 | 1.62519302927e-05 | 0.454545454545 | CNOT6L CNOT10 CNOT9 CNOT1 TNKS1BP1 | Ciliary landscape |
| GO:0034248 | 1.71781877427e-05 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | regulation of cellular amide metabolic process |
| GO:0009892 | 2.19713179411e-05 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of metabolic process |
| GO:0004518 | 3.8623857738e-05 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | nuclease activity |
| GO:0036464 | 6.95814165825e-05 | 0.545454545455 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT2 | cytoplasmic ribonucleoprotein granule |
| GO:0035770 | 9.58847192282e-05 | 0.545454545455 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT2 | ribonucleoprotein granule |
| GO:0006950 | 0.000263384715812 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | response to stress |
| GO:0033147 | 0.000523632447094 | 0.272727272727 | CNOT1 CNOT9 CNOT2 | negative regulation of intracellular estrogen receptor signaling pathway |
| GO:0010468 | 0.000651824721407 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of gene expression |
| GO:0006412 | 0.000797459259432 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | translation |
| GO:0043043 | 0.00108056036329 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | peptide biosynthetic process |
| GO:0140098 | 0.00157740939092 | 0.545454545455 | CNOT6L CNOT6 CNOT8 CNOT1 CNOT2 CNOT7 | catalytic activity, acting on RNA |
| GO:0016070 | 0.0016280313829 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | RNA metabolic process |
| GO:0048523 | 0.00234687699329 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of cellular process |
| GO:1902117 | 0.00249850568129 | 0.363636363636 | CNOT6L CNOT6 CNOT1 CNOT2 | positive regulation of organelle assembly |
| GO:0043604 | 0.00375691828179 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | amide biosynthetic process |
| GO:0006518 | 0.00387949976765 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | peptide metabolic process |
| GO:0032269 | 0.00392110870745 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | negative regulation of cellular protein metabolic process |
| GO:0090304 | 0.00577667484778 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | nucleic acid metabolic process |
| GO:0051248 | 0.0061085860917 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | negative regulation of protein metabolic process |
| GO:0010467 | 0.0102654244082 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | gene expression |
| GO:0048519 | 0.0105141344093 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | negative regulation of biological process |
| GO:0048522 | 0.0108327209646 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | positive regulation of cellular process |
| GO:2000036 | 0.0121541034417 | 0.272727272727 | CNOT3 CNOT2 CNOT1 | regulation of stem cell population maintenance |
| GO:0007165 | 0.0170824338285 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signal transduction |
| GO:0006139 | 0.0193594635595 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | nucleobase-containing compound metabolic process |
| GO:0043603 | 0.0229775304998 | 0.636363636364 | CNOT7 CNOT3 CNOT9 CNOT8 CNOT1 CNOT10 CNOT2 | cellular amide metabolic process |
| GO:0060255 | 0.0277169776931 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | regulation of macromolecule metabolic process |
| GO:0046483 | 0.0283299452848 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | heterocycle metabolic process |
| GO:0006725 | 0.0294323659787 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cellular aromatic compound metabolic process |
| GO:0023052 | 0.0406090450737 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | signaling |
| GO:0007154 | 0.0409322704174 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | cell communication |
| GO:0033144 | 0.0434092832834 | 0.272727272727 | CNOT1 CNOT9 CNOT2 | negative regulation of intracellular steroid hormone receptor signaling pathway |
| GO:1901360 | 0.0448799691044 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | organic cyclic compound metabolic process |
| GO:0048518 | 0.0471650468182 | 1.0 | CNOT6L CNOT6 CNOT3 TNKS1BP1 CNOT2 CNOT11 CNOT8 CNOT1 CNOT10 CNOT9 CNOT7 | positive regulation of biological process |
| GO:0033146 | 0.0485987949639 | 0.272727272727 | CNOT1 CNOT9 CNOT2 | regulation of intracellular estrogen receptor signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CNOT9 | CNOT1 | 1.0 | 0.949 | hein_WMM youn (CNOT1,CNOT9) bioplex_WMM boldt youn_WMM hein (CNOT1) Malo gupta_WMM fraction boldt_WMM |
| CNOT9 | CNOT3 | 1.0 | 0.949 | hein_WMM youn (CNOT9) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| CNOT2 | CNOT11 | 1.0 | 0.949 | hein_WMM youn (CNOT2) bioplex (CNOT11) bioplex_WMM boldt youn_WMM hein (CNOT2) gupta_WMM boldt_WMM |
| CNOT2 | CNOT3 | 1.0 | 0.949 | hein_WMM youn (CNOT2) bioplex_WMM boldt youn_WMM hein (CNOT2) Malo gupta_WMM fraction boldt_WMM |
| CNOT7 | CNOT1 | 1.0 | 0.949 | hein_WMM youn (CNOT1,CNOT7) bioplex (CNOT7) bioplex_WMM Guru boldt youn_WMM hein (CNOT1) Malo gupta_WMM fraction boldt_WMM |
| CNOT7 | CNOT9 | 1.0 | 0.949 | hein_WMM youn (CNOT7,CNOT9) bioplex (CNOT7) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| CNOT7 | CNOT3 | 1.0 | 0.949 | hein_WMM youn (CNOT7) bioplex (CNOT7) bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| CNOT7 | CNOT2 | 1.0 | 0.949 | hein_WMM youn (CNOT2,CNOT7) bioplex (CNOT7) bioplex_WMM boldt youn_WMM hein (CNOT2) gupta_WMM boldt_WMM |
| CNOT11 | CNOT1 | 1.0 | 0.949 | hein_WMM youn (CNOT1) bioplex (CNOT11) bioplex_WMM boldt youn_WMM hein (CNOT1) gupta_WMM boldt_WMM |
| CNOT7 | CNOT6L | 1.0 | 0.949 | hein_WMM youn (CNOT6L,CNOT7) bioplex (CNOT7) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT7 | CNOT6 | 1.0 | 0.949 | hein_WMM youn (CNOT7) bioplex (CNOT7) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT3 | CNOT1 | 1.0 | 0.949 | hein_WMM youn (CNOT1) bioplex_WMM Guru boldt youn_WMM hein (CNOT1) Malo gupta_WMM fraction boldt_WMM |
| CNOT7 | CNOT11 | 1.0 | 0.949 | hein_WMM youn (CNOT7) bioplex (CNOT11,CNOT7) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CNOT9 | CNOT2 | 1.0 | 0.949 | hein_WMM youn (CNOT2,CNOT9) bioplex_WMM boldt youn_WMM hein (CNOT2) gupta_WMM boldt_WMM |
| CNOT10 | CNOT2 | 1.0 | 0.949 | hein_WMM youn (CNOT2) bioplex_WMM boldt youn_WMM hein (CNOT2) gupta_WMM boldt_WMM |
| CNOT6L | CNOT2 | 1.0 | 0.949 | hein_WMM youn (CNOT2,CNOT6L) bioplex_WMM boldt youn_WMM hein (CNOT2) boldt_WMM |
| CNOT7 | CNOT10 | 0.999 | 0.949 | hein_WMM youn (CNOT7) bioplex (CNOT7) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CNOT2 | CNOT8 | 0.999 | 0.949 | hein_WMM youn (CNOT2) bioplex_WMM boldt youn_WMM hein (CNOT2) boldt_WMM |
| CNOT10 | CNOT1 | 0.998 | 0.944 | hein_WMM youn (CNOT1) bioplex_WMM boldt youn_WMM hein (CNOT1) gupta_WMM boldt_WMM |
| CNOT2 | TNKS1BP1 | 0.997 | 0.934 | hein_WMM youn (CNOT2) bioplex_WMM boldt youn_WMM hein (CNOT2,TNKS1BP1) boldt_WMM |
| CNOT7 | TNKS1BP1 | 0.997 | 0.93 | hein_WMM youn (CNOT7) bioplex (CNOT7) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT10 | CNOT11 | 0.997 | 0.929 | hein_WMM bioplex (CNOT11) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CNOT6L | CNOT11 | 0.997 | 0.929 | hein_WMM youn (CNOT6L) bioplex (CNOT11) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT9 | CNOT11 | 0.996 | 0.926 | hein_WMM youn (CNOT9) bioplex (CNOT11) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CNOT1 | CNOT8 | 0.995 | 0.924 | hein_WMM youn (CNOT1) bioplex_WMM boldt youn_WMM hein (CNOT1) boldt_WMM |
| CNOT2 | CNOT6 | 0.988 | 0.901 | hein_WMM youn (CNOT2) bioplex_WMM boldt youn_WMM hein (CNOT2) boldt_WMM |
| CNOT2 | CNOT1 | 0.976 | 0.889 | hein_WMM youn (CNOT1,CNOT2) bioplex_WMM boldt youn_WMM hein (CNOT1,CNOT2) gupta_WMM boldt_WMM |
| CNOT6L | CNOT1 | 0.973 | 0.886 | hein_WMM youn (CNOT1,CNOT6L) bioplex_WMM boldt youn_WMM hein (CNOT1) boldt_WMM |
| CNOT11 | CNOT6 | 0.972 | 0.886 | hein_WMM bioplex (CNOT11) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT9 | TNKS1BP1 | 0.969 | 0.88 | hein_WMM youn (CNOT9) bioplex_WMM boldt youn_WMM hein (TNKS1BP1) boldt_WMM |
| CNOT3 | CNOT11 | 0.96 | 0.865 | hein_WMM bioplex (CNOT11) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CNOT6L | CNOT3 | 0.95 | 0.857 | hein_WMM youn (CNOT6L) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT11 | TNKS1BP1 | 0.92 | 0.844 | hein_WMM bioplex (CNOT11) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT11 | CNOT8 | 0.884 | 0.817 | hein_WMM bioplex (CNOT11) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT1 | TNKS1BP1 | 0.836 | 0.779 | hein_WMM youn (CNOT1) bioplex_WMM boldt youn_WMM hein (CNOT1,TNKS1BP1) boldt_WMM |
| CNOT6L | TNKS1BP1 | 0.628 | 0.68 | hein_WMM youn (CNOT6L) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT3 | TNKS1BP1 | 0.595 | 0.666 | hein_WMM bioplex_WMM boldt youn_WMM hein (TNKS1BP1) boldt_WMM |
| CNOT6L | CNOT8 | 0.574 | 0.657 | hein_WMM youn (CNOT6L) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT9 | CNOT6L | 0.449 | 0.593 | hein_WMM youn (CNOT6L,CNOT9) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT9 | CNOT10 | 0.357 | 0.539 | hein_WMM youn (CNOT9) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CNOT6L | CNOT10 | 0.332 | 0.523 | hein_WMM youn (CNOT6L) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT6L | CNOT6 | 0.331 | 0.521 | hein_WMM youn (CNOT6L) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT9 | CNOT8 | 0.282 | 0.487 | hein_WMM youn (CNOT9) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT1 | CNOT6 | 0.269 | 0.483 | hein_WMM bioplex_WMM boldt youn_WMM hein (CNOT1) boldt_WMM |
| CNOT8 | TNKS1BP1 | 0.264 | 0.481 | hein_WMM bioplex_WMM boldt youn_WMM hein (TNKS1BP1) boldt_WMM |
| CNOT9 | CNOT6 | 0.244 | 0.468 | hein_WMM youn (CNOT9) bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT3 | CNOT6 | 0.071 | 0.351 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT10 | CNOT3 | 0.07 | 0.348 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CNOT10 | CNOT6 | 0.069 | 0.349 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT10 | CNOT8 | 0.064 | 0.348 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT3 | CNOT8 | 0.061 | 0.339 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT8 | CNOT6 | 0.057 | 0.324 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT6 | TNKS1BP1 | 0.054 | 0.298 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT7 | CNOT8 | 0.051 | 0.3 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| CNOT10 | TNKS1BP1 | 0.041 | 0.27 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_01257 has an average edge precision of 0.75 which is ranked 1155 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CNOT2 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_05227 |
| CNOT1 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_06831 |
| CNOT6 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 |
| CNOT3 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_06831 |
| CNOT8 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 |
| CNOT9 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_06831 |
| TNKS1BP1 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 |
| CNOT11 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_05227 |
| CNOT7 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_06831 HuMAP2_06839 |
| CNOT6L | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 |
| CNOT10 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 |