hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01270
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP6AP2 | Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adaptor) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) | UniProt NCBI |
| ATP6AP1 | V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1) | UniProt NCBI |
| ATP6V0A1 | V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) | UniProt NCBI |
| ATP6V0C | V-type proton ATPase 16 kDa proteolipid subunit (V-ATPase 16 kDa proteolipid subunit) (Vacuolar proton pump 16 kDa proteolipid subunit) | UniProt NCBI |
| VMA21 | Vacuolar ATPase assembly integral membrane protein VMA21 (Myopathy with excessive autophagy protein) | UniProt NCBI |
| TCIRG1 | V-type proton ATPase 116 kDa subunit a isoform 3 (V-ATPase 116 kDa isoform a3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3) | UniProt NCBI |
| ATP6V0D1 | V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1) | UniProt NCBI |
| TMEM199 | Transmembrane protein 199 | UniProt NCBI |
| ATP6V0D2 | V-type proton ATPase subunit d 2 (V-ATPase subunit d 2) (Vacuolar proton pump subunit d 2) | UniProt NCBI |
| CCDC115 | Coiled-coil domain-containing protein 115 | UniProt NCBI |
| ATP6V0A2 | V-type proton ATPase 116 kDa subunit a isoform 2 (V-ATPase 116 kDa isoform a2) (Lysosomal H(+)-transporting ATPase V0 subunit a2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0033176 | 2.55909676686e-21 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0A2 TCIRG1 ATP6AP2 ATP6V0D1 ATP6AP1 | proton-transporting V-type ATPase complex |
| GO:0016471 | 3.34029486556e-18 | 0.727272727273 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0A2 ATP6AP2 ATP6V0D1 TCIRG1 | vacuolar proton-transporting V-type ATPase complex |
| GO:0016469 | 9.67955546119e-18 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0A2 TCIRG1 ATP6AP2 ATP6V0D1 ATP6AP1 | proton-transporting two-sector ATPase complex |
| GO:0045851 | 1.23179416111e-17 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | pH reduction |
| REAC:R-HSA-77387 | 7.74430546028e-16 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Insulin receptor recycling |
| GO:0030641 | 1.56047125318e-15 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | regulation of cellular pH |
| GO:0006885 | 2.34274188883e-15 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | regulation of pH |
| REAC:R-HSA-917977 | 3.48824050607e-15 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Transferrin endocytosis and recycling |
| GO:0030004 | 7.17311432061e-15 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | cellular monovalent inorganic cation homeostasis |
| GO:0051452 | 1.30723293835e-14 | 0.727272727273 | ATP6V0A1 CCDC115 TMEM199 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6V0D1 TCIRG1 | intracellular pH reduction |
| GO:0007035 | 2.57364598068e-14 | 0.636363636364 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0A2 ATP6V0D1 TCIRG1 | vacuolar acidification |
| KEGG:05110 | 3.36497883481e-14 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Vibrio cholerae infection |
| GO:0055067 | 8.23831637093e-14 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | monovalent inorganic cation homeostasis |
| KEGG:05323 | 1.05790670868e-13 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Rheumatoid arthritis |
| KEGG:05120 | 1.98773332772e-13 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Epithelial cell signaling in Helicobacter pylori infection |
| KEGG:04966 | 2.42009600836e-13 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | Collecting duct acid secretion |
| REAC:R-HSA-917937 | 3.93483822305e-13 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Iron uptake and transport |
| REAC:R-HSA-74752 | 7.57076264026e-13 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Signaling by Insulin receptor |
| GO:0051453 | 8.8819189167e-13 | 0.727272727273 | ATP6V0A1 CCDC115 TMEM199 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6V0D1 TCIRG1 | regulation of intracellular pH |
| GO:0033572 | 2.17483691489e-12 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | transferrin transport |
| REAC:R-HSA-1222556 | 6.01653050862e-12 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | ROS and RNS production in phagocytes |
| GO:0046961 | 7.61364007486e-12 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | proton-transporting ATPase activity, rotational mechanism |
| KEGG:00190 | 2.37000350615e-11 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Oxidative phosphorylation |
| KEGG:04142 | 2.37000350615e-11 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Lysosome |
| KEGG:04145 | 6.197904076e-11 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Phagosome |
| GO:0006826 | 1.02773416653e-10 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | iron ion transport |
| KEGG:05152 | 1.31211794019e-10 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Tuberculosis |
| KEGG:04721 | 1.34729711691e-10 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | Synaptic vesicle cycle |
| GO:0044769 | 2.68630656928e-10 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism |
| GO:0090383 | 4.48738226367e-10 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | phagosome acidification |
| REAC:R-HSA-983712 | 1.01028121481e-09 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Ion channel transport |
| GO:0005774 | 1.28629124425e-09 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 ATP6V0D1 TCIRG1 | vacuolar membrane |
| GO:0036295 | 1.74499729133e-09 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | cellular response to increased oxygen levels |
| GO:0036296 | 1.74499729133e-09 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | response to increased oxygen levels |
| GO:0000041 | 2.27826956771e-09 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | transition metal ion transport |
| GO:0009678 | 2.4549713949e-09 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | pyrophosphate hydrolysis-driven proton transmembrane transporter activity |
| GO:0090382 | 2.94511633785e-09 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | phagosome maturation |
| GO:0005773 | 2.98232875365e-09 | 0.909090909091 | ATP6V0A1 VMA21 TMEM199 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 ATP6V0D1 TCIRG1 CCDC115 | vacuole |
| GO:0030670 | 4.92891182764e-09 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | phagocytic vesicle membrane |
| GO:0008286 | 5.13649114337e-09 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | insulin receptor signaling pathway |
| GO:0030003 | 1.78434719626e-08 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | cellular cation homeostasis |
| GO:0006873 | 2.08652397528e-08 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | cellular ion homeostasis |
| KEGG:05165 | 2.29047835638e-08 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Human papillomavirus infection |
| GO:0019829 | 3.8849138447e-08 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | ATPase-coupled cation transmembrane transporter activity |
| GO:0044437 | 4.12721753776e-08 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 ATP6V0D1 TCIRG1 | vacuolar part |
| GO:0055080 | 4.29970588674e-08 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | cation homeostasis |
| GO:0098771 | 4.85620207675e-08 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | inorganic ion homeostasis |
| GO:0042625 | 6.08126461795e-08 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | ATPase-coupled ion transmembrane transporter activity |
| GO:0055082 | 8.07856796574e-08 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | cellular chemical homeostasis |
| GO:0032869 | 9.37813336643e-08 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to insulin stimulus |
| GO:0050801 | 1.13048130093e-07 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | ion homeostasis |
| GO:0032868 | 1.32387984281e-07 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | response to insulin |
| GO:0019725 | 4.45777553013e-07 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | cellular homeostasis |
| GO:0045335 | 4.84380124633e-07 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | phagocytic vesicle |
| REAC:R-HSA-9006934 | 7.11877233268e-07 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Signaling by Receptor Tyrosine Kinases |
| GO:0071375 | 9.34676904569e-07 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to peptide hormone stimulus |
| GO:0015078 | 1.37764232083e-06 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | proton transmembrane transporter activity |
| GO:0042626 | 1.46805114361e-06 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | ATPase-coupled transmembrane transporter activity |
| GO:0015399 | 1.88061112316e-06 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | primary active transmembrane transporter activity |
| GO:0043434 | 2.18889569553e-06 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | response to peptide hormone |
| GO:0098805 | 2.3648955658e-06 | 0.909090909091 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 | whole membrane |
| GO:0048878 | 2.62141380667e-06 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | chemical homeostasis |
| GO:1901653 | 3.27923083026e-06 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to peptide |
| GO:0030666 | 3.73617620317e-06 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | endocytic vesicle membrane |
| GO:0006879 | 7.89839487997e-06 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | cellular iron ion homeostasis |
| GO:1901652 | 8.76603670666e-06 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | response to peptide |
| GO:0030659 | 1.01358582174e-05 | 0.727272727273 | ATP6V0A1 TMEM199 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 ATP6V0D1 TCIRG1 | cytoplasmic vesicle membrane |
| GO:0010008 | 1.05037255725e-05 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | endosome membrane |
| REAC:R-HSA-382551 | 1.06969970019e-05 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Transport of small molecules |
| GO:0000323 | 1.18977813141e-05 | 0.727272727273 | ATP6V0A1 VMA21 ATP6V0D1 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 TCIRG1 | lytic vacuole |
| GO:0005764 | 1.18977813141e-05 | 0.727272727273 | ATP6V0A1 VMA21 ATP6V0D1 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 TCIRG1 | lysosome |
| GO:0012506 | 1.26739891123e-05 | 0.727272727273 | ATP6V0A1 TMEM199 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 ATP6V0D1 TCIRG1 | vesicle membrane |
| GO:0055072 | 1.29464494433e-05 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | iron ion homeostasis |
| GO:0033181 | 1.49850650438e-05 | 0.272727272727 | ATP6V0D1 ATP6V0D2 ATP6AP1 | plasma membrane proton-transporting V-type ATPase complex |
| GO:0098588 | 1.71560437595e-05 | 0.909090909091 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 | bounding membrane of organelle |
| GO:0098796 | 1.80561052152e-05 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0A2 TCIRG1 ATP6AP2 ATP6V0D1 ATP6AP1 | membrane protein complex |
| GO:0044440 | 2.65861574232e-05 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | endosomal part |
| GO:0031090 | 5.83518106303e-05 | 1.0 | ATP6V0A1 VMA21 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 CCDC115 | organelle membrane |
| GO:0022853 | 6.08972561762e-05 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | active ion transmembrane transporter activity |
| GO:0031410 | 7.46834789937e-05 | 0.909090909091 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 | cytoplasmic vesicle |
| GO:0097708 | 7.5161485101e-05 | 0.909090909091 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 | intracellular vesicle |
| GO:0071417 | 8.67959832245e-05 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to organonitrogen compound |
| GO:0046916 | 8.87162661122e-05 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | cellular transition metal ion homeostasis |
| GO:0044433 | 9.39816257148e-05 | 0.818181818182 | ATP6V0A1 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 | cytoplasmic vesicle part |
| GO:0055076 | 0.000161642621208 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | transition metal ion homeostasis |
| GO:0032870 | 0.000162308009185 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to hormone stimulus |
| REAC:R-HSA-168249 | 0.000164141821137 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 TCIRG1 | Innate Immune System |
| GO:0030139 | 0.000178487669494 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | endocytic vesicle |
| GO:1901699 | 0.000185830312075 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to nitrogen compound |
| GO:0042592 | 0.000242065537887 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | homeostatic process |
| GO:0022804 | 0.000305166109071 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | active transmembrane transporter activity |
| KEGG:01100 | 0.000379538868165 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Metabolic pathways |
| GO:0009725 | 0.000460742706642 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | response to hormone |
| GO:0016236 | 0.000522786175354 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | macroautophagy |
| GO:0015077 | 0.000586932655257 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | monovalent inorganic cation transmembrane transporter activity |
| GO:0098852 | 0.000628457929619 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | lytic vacuole membrane |
| GO:0005765 | 0.000628457929619 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | lysosomal membrane |
| GO:0007169 | 0.000797459259432 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | transmembrane receptor protein tyrosine kinase signaling pathway |
| GO:0030001 | 0.000923745180313 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | metal ion transport |
| GO:0010243 | 0.00108056036329 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | response to organonitrogen compound |
| HP:0012345 | 0.00118787652565 | 0.272727272727 | TMEM199 CCDC115 ATP6V0A2 | Abnormal glycosylation |
| GO:0044425 | 0.00126696941495 | 1.0 | ATP6V0A1 VMA21 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 CCDC115 | membrane part |
| GO:0016241 | 0.00173715197332 | 0.454545454545 | ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6V0A1 | regulation of macroautophagy |
| GO:0101003 | 0.00197654057291 | 0.363636363636 | TCIRG1 ATP6V0C ATP6AP2 ATP6V0A1 | ficolin-1-rich granule membrane |
| GO:0012505 | 0.00200940239603 | 1.0 | ATP6V0A1 VMA21 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 CCDC115 | endomembrane system |
| GO:0071453 | 0.00227870762203 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | cellular response to oxygen levels |
| GO:1901698 | 0.00241114215782 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | response to nitrogen compound |
| GO:0005768 | 0.00264105961936 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | endosome |
| CORUM:6888 | 0.00303854694462 | 0.181818181818 | ATP6V0D1 ATP6V0C | v-ATPase-Ragulator-AXIN/LKB1-AMPK complex |
| GO:0007039 | 0.00328477723547 | 0.272727272727 | TMEM199 CCDC115 TCIRG1 | protein catabolic process in the vacuole |
| HP:0003155 | 0.00450119944103 | 0.272727272727 | TMEM199 CCDC115 TCIRG1 | Elevated alkaline phosphatase |
| GO:1901701 | 0.00454473091437 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to oxygen-containing compound |
| GO:0034220 | 0.00473767298743 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | ion transmembrane transport |
| HP:0010837 | 0.00546073932307 | 0.181818181818 | TMEM199 CCDC115 | Decreased serum ceruloplasmin |
| GO:0006812 | 0.00558069547565 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cation transport |
| HP:0004379 | 0.00566139280495 | 0.272727272727 | TMEM199 CCDC115 TCIRG1 | Abnormality of alkaline phosphatase activity |
| GO:1902600 | 0.00640008701607 | 0.363636363636 | TCIRG1 ATP6AP1 ATP6V0C ATP6V0D1 | proton transmembrane transport |
| GO:0061919 | 0.00691594933774 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | process utilizing autophagic mechanism |
| GO:0006914 | 0.00691594933774 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | autophagy |
| GO:0007167 | 0.00758065267518 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | enzyme linked receptor protein signaling pathway |
| GO:0070482 | 0.00944214638415 | 0.454545454545 | TMEM199 ATP6AP1 CCDC115 ATP6V0A2 ATP6V0D1 | response to oxygen levels |
| GO:0022890 | 0.00980485486812 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | inorganic cation transmembrane transporter activity |
| GO:0065008 | 0.0141448886145 | 0.909090909091 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 | regulation of biological quality |
| REAC:R-HSA-168256 | 0.0147110658917 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0D2 ATP6V0C ATP6AP2 ATP6V0A2 TCIRG1 | Immune System |
| GO:0008324 | 0.0161616111849 | 0.545454545455 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 TCIRG1 | cation transmembrane transporter activity |
| GO:0005215 | 0.0204743972809 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | transporter activity |
| GO:1901700 | 0.0208171394913 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | response to oxygen-containing compound |
| HP:0005425 | 0.0239692279081 | 0.181818181818 | TCIRG1 ATP6V0A2 | Recurrent sinopulmonary infections |
| HP:0032245 | 0.025837606984 | 0.272727272727 | TMEM199 CCDC115 ATP6V0A2 | Abnormal metabolism |
| GO:0071495 | 0.0289971506624 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | cellular response to endogenous stimulus |
| REAC:R-HSA-162582 | 0.0306388368258 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | Signal Transduction |
| GO:0010506 | 0.0350066109779 | 0.454545454545 | ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6V0A1 | regulation of autophagy |
| GO:0055085 | 0.0379955428856 | 0.636363636364 | ATP6V0A1 ATP6V0D1 ATP6V0C ATP6V0D2 ATP6V0A2 ATP6AP1 TCIRG1 | transmembrane transport |
| GO:0070887 | 0.0420755492267 | 0.818181818182 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6V0A2 ATP6V0D1 ATP6AP1 | cellular response to chemical stimulus |
| REAC:R-HSA-6798695 | 0.0425763699123 | 0.363636363636 | TCIRG1 ATP6V0C ATP6AP2 ATP6V0A1 | Neutrophil degranulation |
| GO:0031982 | 0.0464899471098 | 0.909090909091 | ATP6V0A1 CCDC115 TMEM199 ATP6V0D2 ATP6V0C TCIRG1 ATP6AP2 ATP6V0A2 ATP6V0D1 ATP6AP1 | vesicle |
| WP:WP623 | 0.0487725579756 | 0.181818181818 | ATP6AP1 ATP6AP2 | Oxidative phosphorylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP6AP2 | ATP6AP1 | 1.0 | 0.949 | hein_WMM bioplex (ATP6AP2) bioplex_WMM youn_WMM hein (ATP6AP2) gupta_WMM |
| ATP6V0D1 | ATP6V0A1 | 1.0 | 0.949 | hein_WMM bioplex (ATP6V0D1) bioplex_WMM Guru fraction |
| ATP6AP2 | CCDC115 | 1.0 | 0.949 | hein_WMM bioplex (ATP6AP2) bioplex_WMM youn_WMM hein (ATP6AP2) gupta_WMM |
| ATP6AP2 | VMA21 | 0.998 | 0.941 | bioplex (ATP6AP2) bioplex_WMM youn_WMM gupta_WMM |
| ATP6AP2 | ATP6V0A1 | 0.964 | 0.873 | hein_WMM bioplex (ATP6AP2) bioplex_WMM hein (ATP6AP2) gupta_WMM |
| TMEM199 | ATP6AP2 | 0.752 | 0.745 | bioplex (ATP6AP2,TMEM199) bioplex_WMM youn_WMM gupta_WMM |
| ATP6V0D1 | ATP6V0A2 | 0.533 | 0.637 | bioplex (ATP6V0A2,ATP6V0D1) bioplex_WMM |
| TMEM199 | CCDC115 | 0.325 | 0.514 | hein_WMM bioplex (TMEM199) bioplex_WMM youn_WMM gupta_WMM |
| ATP6V0A1 | ATP6V0A2 | 0.324 | 0.512 | bioplex (ATP6V0A2) bioplex_WMM gupta_WMM |
| TMEM199 | VMA21 | 0.301 | 0.496 | bioplex (TMEM199) bioplex_WMM youn_WMM gupta_WMM |
| ATP6AP2 | ATP6V0D1 | 0.19 | 0.442 | hein_WMM bioplex (ATP6AP2,ATP6V0D1) bioplex_WMM hein (ATP6AP2) |
| CCDC115 | ATP6V0A2 | 0.165 | 0.421 | bioplex (ATP6V0A2) bioplex_WMM gupta_WMM |
| ATP6AP2 | ATP6V0A2 | 0.151 | 0.411 | bioplex (ATP6AP2,ATP6V0A2) bioplex_WMM gupta_WMM |
| TMEM199 | ATP6V0A2 | 0.11 | 0.38 | bioplex (ATP6V0A2,TMEM199) bioplex_WMM gupta_WMM |
| ATP6V0D1 | ATP6V0D2 | 0.103 | 0.366 | bioplex (ATP6V0D1,ATP6V0D2) bioplex_WMM |
| TMEM199 | ATP6AP1 | 0.094 | 0.356 | hein_WMM bioplex (TMEM199) bioplex_WMM youn_WMM gupta_WMM |
| ATP6V0D2 | TCIRG1 | 0.094 | 0.356 | bioplex (ATP6V0D2) bioplex_WMM |
| ATP6V0D1 | CCDC115 | 0.087 | 0.353 | hein_WMM bioplex (ATP6V0D1) bioplex_WMM |
| ATP6AP1 | ATP6V0A2 | 0.061 | 0.336 | bioplex (ATP6V0A2) bioplex_WMM gupta_WMM |
| ATP6V0D2 | VMA21 | 0.054 | 0.305 | bioplex (ATP6V0D2) bioplex_WMM |
| ATP6V0D2 | ATP6V0C | 0.051 | 0.296 | bioplex (ATP6V0D2) bioplex_WMM |
| VMA21 | ATP6V0A2 | 0.05 | 0.297 | bioplex (ATP6V0A2) bioplex_WMM gupta_WMM |
| ATP6V0D2 | CCDC115 | 0.042 | 0.27 | bioplex (ATP6V0D2) bioplex_WMM |
| ATP6V0D2 | ATP6V0A2 | 0.042 | 0.27 | bioplex (ATP6V0A2,ATP6V0D2) bioplex_WMM |
| ATP6AP2 | TCIRG1 | 0.041 | 0.271 | bioplex (ATP6AP2) bioplex_WMM |
| TMEM199 | ATP6V0D1 | 0.037 | 0.267 | hein_WMM bioplex (ATP6V0D1,TMEM199) bioplex_WMM |
| ATP6V0D1 | VMA21 | 0.036 | 0.264 | bioplex (ATP6V0D1) bioplex_WMM |
| ATP6AP2 | ATP6V0C | 0.035 | 0.265 | bioplex (ATP6AP2,ATP6V0C) bioplex_WMM gupta_WMM |
| TMEM199 | ATP6V0D2 | 0.034 | 0.264 | bioplex (ATP6V0D2) bioplex_WMM |
| ATP6V0D2 | ATP6V0A1 | 0.033 | 0.253 | bioplex (ATP6V0D2) bioplex_WMM |
| TMEM199 | ATP6V0C | 0.032 | 0.244 | bioplex (TMEM199) bioplex_WMM gupta_WMM |
| VMA21 | ATP6V0C | 0.03 | 0.233 | bioplex (ATP6V0C) bioplex_WMM gupta_WMM |
| ATP6AP1 | CCDC115 | 0.029 | 0.232 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ATP6V0D1 | TCIRG1 | 0.027 | 0.228 | hein_WMM bioplex (ATP6V0D1) bioplex_WMM |
| ATP6V0D1 | ATP6V0C | 0.027 | 0.228 | bioplex (ATP6V0C,ATP6V0D1) bioplex_WMM |
| TMEM199 | ATP6V0A1 | 0.027 | 0.231 | hein_WMM bioplex (TMEM199) bioplex_WMM gupta_WMM |
| ATP6V0D1 | ATP6AP1 | 0.026 | 0.216 | hein_WMM bioplex (ATP6V0D1) bioplex_WMM |
| ATP6V0A2 | ATP6V0C | 0.025 | 0.211 | bioplex (ATP6V0A2,ATP6V0C) bioplex_WMM gupta_WMM |
| VMA21 | CCDC115 | 0.02 | 0.185 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ATP6AP1 | VMA21 | 0.019 | 0.185 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ATP6V0A1 | CCDC115 | 0.019 | 0.183 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| CCDC115 | ATP6V0C | 0.014 | 0.137 | bioplex_WMM gupta_WMM WMM_only |
| ATP6AP1 | ATP6V0D2 | 0.013 | 0.141 | bioplex (ATP6V0D2) bioplex_WMM |
| TMEM199 | TCIRG1 | 0.012 | 0.149 | hein_WMM bioplex_WMM WMM_only |
| TCIRG1 | ATP6V0C | 0.011 | 0.141 | bioplex_WMM WMM_only |
| VMA21 | TCIRG1 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| ATP6AP1 | ATP6V0C | 0.01 | 0.141 | bioplex (ATP6V0C) bioplex_WMM gupta_WMM |
| CCDC115 | TCIRG1 | 0.01 | 0.14 | hein_WMM bioplex_WMM WMM_only |
| ATP6V0A1 | VMA21 | 0.01 | 0.1 | bioplex_WMM gupta_WMM WMM_only |
| ATP6V0A2 | TCIRG1 | 0.009 | 0.109 | bioplex_WMM WMM_only |
| ATP6AP1 | TCIRG1 | 0.008 | 0.085 | hein_WMM bioplex_WMM WMM_only |
| ATP6V0A1 | TCIRG1 | 0.008 | 0.082 | hein_WMM bioplex_WMM WMM_only |
| ATP6AP1 | ATP6V0A1 | 0.008 | 0.081 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| ATP6V0A1 | ATP6V0C | 0.008 | 0.061 | bioplex (ATP6V0C) bioplex_WMM gupta_WMM |
| ATP6AP2 | ATP6V0D2 | 0.0 | 0.012 | bioplex (ATP6AP2,ATP6V0D2) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_01270 has an average edge precision of 0.326 which is ranked 4269 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP6AP2 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_04327 HuMAP2_05361 HuMAP2_05879 HuMAP2_06410 |
| ATP6AP1 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_04327 HuMAP2_05361 |
| ATP6V0A1 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_02034 HuMAP2_02651 HuMAP2_04677 |
| ATP6V0C | HuMAP2_01018 HuMAP2_01270 |
| VMA21 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_04327 |
| TCIRG1 | HuMAP2_01018 HuMAP2_01270 HuMAP2_05879 |
| ATP6V0D1 | HuMAP2_00515 HuMAP2_00772 HuMAP2_01018 HuMAP2_01065 HuMAP2_01270 HuMAP2_02034 HuMAP2_02651 HuMAP2_04677 HuMAP2_06925 |
| TMEM199 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_04327 |
| ATP6V0D2 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 |
| CCDC115 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_04327 |
| ATP6V0A2 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_02034 HuMAP2_04677 |