hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01280
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| STRADB | STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2) | UniProt NCBI |
| CAB39 | Calcium-binding protein 39 (MO25alpha) (Protein Mo25) | UniProt NCBI |
| CAB39L | Calcium-binding protein 39-like (Antigen MLAA-34) (MO25beta) (Mo25-like protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-380972 | 1.47287948045e-06 | 1.0 | CAB39L STRADB CAB39 | Energy dependent regulation of mTOR by LKB1-AMPK |
| REAC:R-HSA-165159 | 4.10886616968e-06 | 1.0 | CAB39L STRADB CAB39 | mTOR signalling |
| KEGG:04152 | 6.85409597589e-06 | 1.0 | CAB39L STRADB CAB39 | AMPK signaling pathway |
| KEGG:04150 | 1.46555920905e-05 | 1.0 | CAB39L STRADB CAB39 | mTOR signaling pathway |
| WP:WP1403 | 0.00192837749058 | 0.666666666667 | STRADB CAB39 | AMP-activated Protein Kinase (AMPK) Signaling |
| WP:WP3932 | 0.0309522486098 | 0.666666666667 | CAB39L CAB39 | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway |
| WP:WP3595 | 0.0428416541517 | 0.333333333333 | STRADB | mir-124 predicted interactions with cell cycle and differentiation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CAB39L | CAB39 | 0.992 | 0.912 | bioplex (CAB39L) bioplex_WMM |
| CAB39 | STRADB | 0.907 | 0.83 | bioplex (STRADB) bioplex_WMM |
Images
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Complex HuMAP2_01280 has an average edge precision of 0.871 which is ranked 687 out of all 6965 complexes.
Related Complexes