hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_01290

Confidence: High

Genename	Protein Name	Links
UFM1	Ubiquitin-fold modifier 1	UniProt NCBI
UBA5	Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)	UniProt NCBI
FH	Fumarate hydratase, mitochondrial (Fumarase) (HsFH) (EC 4.2.1.2)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HP:0002059	0.0111473474447	1.0	UBA5 UFM1 FH	Cerebral atrophy
HP:0007369	0.0114971354871	1.0	UBA5 UFM1 FH	Atrophy/Degeneration affecting the cerebrum
GO:1990564	0.0135228859698	0.666666666667	UBA5 UFM1	protein polyufmylation
GO:1990592	0.0135228859698	0.666666666667	UBA5 UFM1	protein K69-linked ufmylation
HP:0012444	0.0151492745266	1.0	UBA5 UFM1 FH	Brain atrophy
GO:0071569	0.020283420769	0.666666666667	UBA5 UFM1	protein ufmylation
HP:0007367	0.0227883181872	1.0	UBA5 UFM1 FH	Atrophy/Degeneration affecting the central nervous system
HP:0002133	0.0409824890748	0.666666666667	UBA5 FH	Status epilepticus
WP:WP4236	0.0499785733994	0.333333333333	FH	Disorders of the Krebs cycle

Protein 1	Protein 2	Score	Precision	Evidence
UFM1	UBA5	0.795	0.761	hein_WMM bioplex (UBA5) bioplex_WMM hein (UBA5)
UFM1	FH	0.635	0.685	bioplex (UFM1) bioplex_WMM fraction
UBA5	FH	0.007	0.002	bioplex_WMM WMM_only treiber_WMM

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ComplexPrecisionDistribution

Complex HuMAP2_01290 has an average edge precision of 0.483 which is ranked 2610 out of all 6965 complexes.

Related Complexes

Genename	Complexes
UFM1	HuMAP2_01176 HuMAP2_01290 HuMAP2_01692 HuMAP2_04645
UBA5	HuMAP2_01290 HuMAP2_01692 HuMAP2_05219
FH	HuMAP2_01290 HuMAP2_02379 HuMAP2_02582 HuMAP2_03864