hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01295
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| THOC5 | THO complex subunit 5 homolog (Functional spliceosome-associated protein 79) (fSAP79) (NF2/meningioma region protein pK1.3) (Placental protein 39.2) (PP39.2) (hTREX90) | UniProt NCBI |
| THOC6 | THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58) | UniProt NCBI |
| THOC1 | THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) | UniProt NCBI |
| THOC2 | THO complex subunit 2 (Tho2) (hTREX120) | UniProt NCBI |
| THOC7 | THO complex subunit 7 homolog (Functional spliceosome-associated protein 24) (fSAP24) (Ngg1-interacting factor 3-like protein 1-binding protein 1) (NIF3L1-binding protein 1) (hTREX30) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:774 | 1.21903689317e-17 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | THO complex |
| CORUM:6160 | 7.31422135901e-17 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | hTREX84 complex |
| CORUM:770 | 2.55997747565e-16 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | TREX complex |
| GO:0000347 | 4.91515675326e-14 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | THO complex |
| GO:0000445 | 4.91515675326e-14 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | THO complex part of transcription export complex |
| GO:0051836 | 1.72030486364e-13 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | translocation of molecules into other organism involved in symbiotic interaction |
| GO:0046784 | 1.72030486364e-13 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | viral mRNA export from host cell nucleus |
| GO:0044417 | 1.72030486364e-13 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | translocation of molecules into host |
| GO:0000346 | 1.05430112357e-11 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | transcription export complex |
| REAC:R-HSA-72187 | 7.7566029859e-11 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 1.72394634729e-10 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 2.55669776128e-10 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 4.84594599934e-10 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | Transport of Mature Transcript to Cytoplasm |
| CORUM:351 | 5.08296361811e-09 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | Spliceosome |
| KEGG:03013 | 5.10275915838e-09 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA transport |
| GO:0044766 | 9.20650884475e-08 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | multi-organism transport |
| GO:1902579 | 9.20650884475e-08 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | multi-organism localization |
| REAC:R-HSA-72203 | 1.40345345848e-07 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0031124 | 4.25745004355e-07 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | mRNA 3'-end processing |
| GO:0071427 | 8.70872110173e-07 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | mRNA-containing ribonucleoprotein complex export from nucleus |
| GO:0006406 | 8.70872110173e-07 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | mRNA export from nucleus |
| GO:0051028 | 1.09897753919e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | mRNA transport |
| GO:0000784 | 1.4332878731e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | nuclear chromosome, telomeric region |
| GO:0051701 | 1.62849460149e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | interaction with host |
| GO:0071426 | 1.69808838788e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | ribonucleoprotein complex export from nucleus |
| GO:0071166 | 1.77004128567e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | ribonucleoprotein complex localization |
| GO:0006405 | 2.43793950738e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA export from nucleus |
| GO:0031123 | 2.7349531731e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA 3'-end processing |
| GO:0000781 | 3.29376042454e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | chromosome, telomeric region |
| GO:0050658 | 4.84634480447e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA transport |
| GO:0050657 | 4.84634480447e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | nucleic acid transport |
| GO:0051236 | 5.3578971163e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | establishment of RNA localization |
| GO:0006611 | 6.30577736298e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | protein export from nucleus |
| GO:0051168 | 9.13428048519e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | nuclear export |
| GO:0015931 | 9.97955469656e-06 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | nucleobase-containing compound transport |
| GO:0006403 | 1.43956026192e-05 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA localization |
| REAC:R-HSA-8953854 | 2.37148320446e-05 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | Metabolism of RNA |
| GO:0031503 | 4.11426271691e-05 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | protein-containing complex localization |
| GO:0006913 | 9.09038692953e-05 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | nucleocytoplasmic transport |
| GO:0051169 | 9.61471171118e-05 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | nuclear transport |
| GO:0098687 | 9.97750059848e-05 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | chromosomal region |
| REAC:R-HSA-73857 | 0.000412889072144 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA Polymerase II Transcription |
| GO:0006397 | 0.00066476318296 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | mRNA processing |
| REAC:R-HSA-74160 | 0.000713316403356 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | Gene expression (Transcription) |
| GO:0044403 | 0.00168572694146 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | symbiotic process |
| GO:0044419 | 0.00221997973486 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | interspecies interaction between organisms |
| GO:0016071 | 0.0124036237668 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | mRNA metabolic process |
| GO:0006396 | 0.0184779947673 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | RNA processing |
| GO:2000002 | 0.0270421395626 | 0.4 | THOC1 THOC5 | negative regulation of DNA damage checkpoint |
| KEGG:03040 | 0.0353865382697 | 0.4 | THOC1 THOC2 | Spliceosome |
| GO:0006886 | 0.0442638282809 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | intracellular protein transport |
| GO:1901977 | 0.0450641792523 | 0.4 | THOC1 THOC5 | negative regulation of cell cycle checkpoint |
| GO:0044454 | 0.046479053704 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | nuclear chromosome part |
| CORUM:0000000 | 0.0474603483533 | 1.0 | THOC7 THOC1 THOC6 THOC2 THOC5 | CORUM root |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| THOC5 | THOC1 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM youn_WMM hein (THOC1,THOC5) Malo fraction |
| THOC2 | THOC1 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM youn_WMM hein (THOC1,THOC2) Malo gupta_WMM fraction |
| THOC1 | THOC6 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM youn_WMM hein (THOC1) Malo fraction |
| THOC7 | THOC1 | 1.0 | 0.949 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM hein (THOC1,THOC7) Malo fraction |
| THOC7 | THOC5 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (THOC5,THOC7) Malo fraction |
| THOC2 | THOC7 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (THOC2,THOC7) Malo gupta_WMM fraction |
| THOC7 | THOC6 | 0.999 | 0.948 | hein_WMM bioplex_WMM youn_WMM hein (THOC7) Malo fraction |
| THOC5 | THOC6 | 0.998 | 0.939 | hein_WMM bioplex_WMM Guru youn_WMM hein (THOC5) Malo fraction |
| THOC2 | THOC6 | 0.993 | 0.918 | hein_WMM bioplex_WMM youn_WMM hein (THOC2) Malo fraction |
| THOC2 | THOC5 | 0.988 | 0.902 | hein_WMM bioplex_WMM youn_WMM hein (THOC2,THOC5) Malo fraction |
Images
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Complex HuMAP2_01295 has an average edge precision of 0.94 which is ranked 396 out of all 6965 complexes.
Related Complexes