hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01304
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SNX2 | Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9) | UniProt NCBI |
| SNX5 | Sorting nexin-5 | UniProt NCBI |
| SNX6 | Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030905 | 3.63274304092e-07 | 1.0 | SNX6 SNX2 SNX5 | retromer, tubulation complex |
| KEGG:04144 | 6.09806140287e-05 | 1.0 | SNX6 SNX2 SNX5 | Endocytosis |
| GO:0030904 | 7.41079580349e-05 | 1.0 | SNX6 SNX2 SNX5 | retromer complex |
| GO:0042147 | 0.00774864090629 | 1.0 | SNX6 SNX2 SNX5 | retrograde transport, endosome to Golgi |
| REAC:R-HSA-432722 | 0.00955880978777 | 0.666666666667 | SNX2 SNX5 | Golgi Associated Vesicle Biogenesis |
| GO:0097422 | 0.0135228859698 | 0.666666666667 | SNX6 SNX5 | tubular endosome |
| REAC:R-HSA-199992 | 0.0170598073203 | 0.666666666667 | SNX2 SNX5 | trans-Golgi Network Vesicle Budding |
| CORUM:1072 | 0.0249904952816 | 0.333333333333 | SNX2 | SNX complex (SNX2), oligomeric |
| MIRNA:hsa-miR-497-3p | 0.0384874919534 | 0.666666666667 | SNX2 SNX5 | hsa-miR-497-3p |
| GO:0016482 | 0.043337807111 | 1.0 | SNX6 SNX2 SNX5 | cytosolic transport |
| CORUM:1058 | 0.0499776345577 | 0.333333333333 | SNX6 | SNX complex (SNX1, SNX6) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SNX2 | SNX6 | 0.993 | 0.918 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| SNX2 | SNX5 | 0.99 | 0.909 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| SNX6 | SNX5 | 0.007 | 0.004 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_01304 has an average edge precision of 0.61 which is ranked 1887 out of all 6965 complexes.
Related Complexes