hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01327
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HSPA1B | Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) | UniProt NCBI |
| DNAJB2 | DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1) | UniProt NCBI |
| RNF115 | E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rabring 7) (Zinc finger protein 364) | UniProt NCBI |
| RLIM | E3 ubiquitin-protein ligase RLIM (EC 2.3.2.27) (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (RING finger protein 12) (RING-type E3 ubiquitin transferase RLIM) (Renal carcinoma antigen NY-REN-43) | UniProt NCBI |
| CYHR1 | Cysteine and histidine-rich protein 1 | UniProt NCBI |
| CPZ | Carboxypeptidase Z (CPZ) (EC 3.4.17.-) | UniProt NCBI |
| DNAJB8 | DnaJ homolog subfamily B member 8 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0090084 | 0.000266683990267 | 0.428571428571 | DNAJB2 HSPA1B DNAJB8 | negative regulation of inclusion body assembly |
| GO:0090083 | 0.000698035893352 | 0.428571428571 | DNAJB2 HSPA1B DNAJB8 | regulation of inclusion body assembly |
| GO:0070841 | 0.00215539204286 | 0.428571428571 | DNAJB2 HSPA1B DNAJB8 | inclusion body assembly |
| MIRNA:hsa-miR-6788-3p | 0.00948680333386 | 0.285714285714 | DNAJB2 HSPA1B | hsa-miR-6788-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DNAJB8 | DNAJB2 | 0.999 | 0.948 | bioplex (DNAJB2,DNAJB8) bioplex_WMM |
| DNAJB2 | RNF115 | 0.057 | 0.322 | bioplex (DNAJB2,RNF115) bioplex_WMM |
| HSPA1B | DNAJB2 | 0.022 | 0.199 | bioplex (DNAJB2) bioplex_WMM boldt |
| HSPA1B | CPZ | 0.021 | 0.195 | bioplex (CPZ) bioplex_WMM |
| HSPA1B | DNAJB8 | 0.021 | 0.188 | bioplex (DNAJB8) bioplex_WMM |
| DNAJB2 | CYHR1 | 0.02 | 0.184 | bioplex (DNAJB2) bioplex_WMM |
| DNAJB2 | RLIM | 0.02 | 0.185 | bioplex (DNAJB2) bioplex_WMM |
| DNAJB8 | CYHR1 | 0.008 | 0.059 | bioplex_WMM WMM_only |
| DNAJB8 | RLIM | 0.007 | 0.006 | bioplex_WMM WMM_only |
| RLIM | CYHR1 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| DNAJB8 | RNF115 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| RNF115 | CYHR1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| HSPA1B | RLIM | 0.007 | 0.002 | bioplex (RLIM) bioplex_WMM |
| HSPA1B | CYHR1 | 0.006 | 0.0 | bioplex_WMM boldt |
| HSPA1B | RNF115 | 0.006 | 0.0 | bioplex (RNF115) bioplex_WMM |
| RNF115 | RLIM | 0.004 | 0.014 | bioplex (RNF115) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_01327 has an average edge precision of 0.145 which is ranked 6741 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HSPA1B | HuMAP2_00689 HuMAP2_01327 HuMAP2_01418 HuMAP2_04281 |
| DNAJB2 | HuMAP2_01075 HuMAP2_01327 HuMAP2_02499 HuMAP2_05539 |
| RNF115 | HuMAP2_01327 HuMAP2_02499 HuMAP2_03184 HuMAP2_03222 HuMAP2_05070 |
| RLIM | HuMAP2_01327 HuMAP2_02499 HuMAP2_05539 |
| CYHR1 | HuMAP2_01327 HuMAP2_02265 |
| CPZ | HuMAP2_00689 HuMAP2_01327 |
| DNAJB8 | HuMAP2_01075 HuMAP2_01327 HuMAP2_02499 HuMAP2_05539 HuMAP2_06339 HuMAP2_06377 |