hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01352
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DCUN1D1 | DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene) | UniProt NCBI |
| UBE2M | NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.-) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M) | UniProt NCBI |
| PITPNA | Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha) | UniProt NCBI |
| KCTD6 | BTB/POZ domain-containing protein KCTD6 (KCASH3 protein) (Potassium channel tetramerization domain-containing protein 6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8951664 | 0.00240260362929 | 0.75 | UBE2M KCTD6 DCUN1D1 | Neddylation |
| CORUM:7371 | 0.0499140284799 | 0.25 | KCTD6 | CUL3-KCTD6 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PITPNA | UBE2M | 0.602 | 0.671 | bioplex_WMM fraction treiber_WMM |
| DCUN1D1 | UBE2M | 0.438 | 0.583 | bioplex (UBE2M) bioplex_WMM |
| KCTD6 | UBE2M | 0.045 | 0.286 | bioplex (UBE2M) bioplex_WMM |
| KCTD6 | DCUN1D1 | 0.009 | 0.09 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01352 has an average edge precision of 0.407 which is ranked 3229 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DCUN1D1 | HuMAP2_01352 HuMAP2_02072 |
| UBE2M | HuMAP2_01352 HuMAP2_01949 HuMAP2_02492 HuMAP2_03398 HuMAP2_04965 HuMAP2_05192 HuMAP2_05548 |
| PITPNA | HuMAP2_00053 HuMAP2_01352 HuMAP2_04441 HuMAP2_05192 |
| KCTD6 | HuMAP2_01352 HuMAP2_03890 HuMAP2_05548 |