hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01363
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NCAPH | Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog) | UniProt NCBI |
| NCAPD2 | Condensin complex subunit 1 (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (Non-SMC condensin I complex subunit D2) (XCAP-D2 homolog) | UniProt NCBI |
| SMC2 | Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) | UniProt NCBI |
| SMC4 | Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) | UniProt NCBI |
| NCAPG | Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog) | UniProt NCBI |
| NCAPD3 | Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) | UniProt NCBI |
| EXPH5 | Exophilin-5 (Synaptotagmin-like protein homolog lacking C2 domains b) (SlaC2-b) (Slp homolog lacking C2 domains b) | UniProt NCBI |
| NCAPG2 | Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (CAP-G2) (hCAP-G2) (Leucine zipper protein 5) (Non-SMC condensin II complex subunit G2) | UniProt NCBI |
| NCAPH2 | Condensin-2 complex subunit H2 (Chromosome-associated protein H2) (hCAP-H2) (Kleisin-beta) (Non-SMC condensin II complex subunit H2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000796 | 5.58773785867e-20 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | condensin complex |
| GO:0007076 | 6.38561078748e-16 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | mitotic chromosome condensation |
| CORUM:167 | 8.53043734036e-16 | 0.555555555556 | NCAPD2 SMC2 NCAPH SMC4 NCAPG | Condensin I complex |
| CORUM:160 | 8.53043734036e-16 | 0.555555555556 | SMC2 NCAPH2 NCAPG2 NCAPD3 SMC4 | Condensin II |
| CORUM:157 | 8.53043734036e-16 | 0.555555555556 | NCAPD2 SMC2 NCAPH SMC4 NCAPG | Condensin I complex |
| CORUM:10 | 8.53043734036e-16 | 0.555555555556 | NCAPD2 SMC2 NCAPH SMC4 NCAPG | Condensin I complex |
| CORUM:159 | 1.79058980098e-14 | 0.555555555556 | NCAPD2 SMC2 NCAPH SMC4 NCAPG | Condensin I-PARP-1-XRCC1 complex |
| GO:0030261 | 2.37981802238e-13 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | chromosome condensation |
| REAC:R-HSA-2514853 | 1.89732358523e-12 | 0.555555555556 | NCAPD2 SMC2 NCAPH SMC4 NCAPG | Condensation of Prometaphase Chromosomes |
| GO:0044815 | 2.73028959778e-11 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | DNA packaging complex |
| REAC:R-HSA-68886 | 2.74693103939e-10 | 0.888888888889 | NCAPD2 NCAPG2 NCAPD3 NCAPH2 SMC4 NCAPH SMC2 NCAPG | M Phase |
| GO:0000793 | 2.13119548181e-09 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | condensed chromosome |
| REAC:R-HSA-69278 | 3.42296831398e-09 | 0.888888888889 | NCAPD2 NCAPG2 NCAPD3 NCAPH2 SMC4 NCAPH SMC2 NCAPG | Cell Cycle, Mitotic |
| GO:0000070 | 9.38607665938e-09 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | mitotic sister chromatid segregation |
| REAC:R-HSA-1640170 | 1.45311860956e-08 | 0.888888888889 | NCAPD2 NCAPG2 NCAPD3 NCAPH2 SMC4 NCAPH SMC2 NCAPG | Cell Cycle |
| GO:0000819 | 3.18474962995e-08 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | sister chromatid segregation |
| GO:0006323 | 3.93768979374e-08 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | DNA packaging |
| REAC:R-HSA-2299718 | 5.66790374605e-08 | 0.555555555556 | SMC2 NCAPH2 NCAPG2 NCAPD3 SMC4 | Condensation of Prophase Chromosomes |
| GO:0098813 | 1.59147664374e-07 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | nuclear chromosome segregation |
| GO:0140014 | 3.05574088316e-07 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | mitotic nuclear division |
| GO:0071103 | 3.78712319498e-07 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | DNA conformation change |
| GO:0007059 | 6.39006387226e-07 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | chromosome segregation |
| REAC:R-HSA-68875 | 1.2362334196e-06 | 0.555555555556 | SMC2 NCAPH2 NCAPG2 NCAPD3 SMC4 | Mitotic Prophase |
| GO:0000280 | 2.6262524884e-06 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | nuclear division |
| GO:0048285 | 5.82786084594e-06 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | organelle fission |
| GO:0010032 | 7.62876038594e-06 | 0.333333333333 | NCAPD2 NCAPH2 NCAPD3 | meiotic chromosome condensation |
| GO:0000799 | 7.62876038594e-06 | 0.333333333333 | NCAPD2 NCAPD3 NCAPH | nuclear condensin complex |
| REAC:R-HSA-68877 | 7.92459631338e-06 | 0.555555555556 | NCAPD2 SMC2 NCAPH SMC4 NCAPG | Mitotic Prometaphase |
| CORUM:5239 | 1.34129279418e-05 | 0.222222222222 | SMC4 SMC2 | CAP(C)-CAP(E) complex |
| CORUM:353 | 4.02261743042e-05 | 0.222222222222 | SMC4 SMC2 | DNA ligase IV-condensin complex |
| CORUM:49 | 0.0002812304202 | 0.222222222222 | SMC4 SMC2 | DNMT3B complex |
| GO:1903047 | 0.000935464171473 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | mitotic cell cycle process |
| CORUM:0000000 | 0.00227951320903 | 0.888888888889 | NCAPD2 NCAPG2 NCAPD3 NCAPH2 SMC4 NCAPH SMC2 NCAPG | CORUM root |
| GO:0000278 | 0.00270098013707 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | mitotic cell cycle |
| GO:0051276 | 0.00574740693261 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | chromosome organization |
| GO:0070192 | 0.0153428859848 | 0.333333333333 | NCAPD2 NCAPH2 NCAPD3 | chromosome organization involved in meiotic cell cycle |
| GO:0022402 | 0.0179882470993 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | cell cycle process |
| GO:0044427 | 0.0384546907947 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | chromosomal part |
| HP:0000340 | 0.0426515825731 | 0.333333333333 | NCAPD2 NCAPD3 NCAPH | Sloping forehead |
| GO:0005694 | 0.049270844601 | 0.777777777778 | NCAPD2 NCAPG NCAPD3 NCAPH2 SMC4 NCAPH SMC2 | chromosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SMC4 | SMC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC4) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NCAPG2 | NCAPD3 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (NCAPD3,NCAPG2) Malo fraction |
| NCAPG2 | NCAPH2 | 1.0 | 0.949 | hein_WMM bioplex (NCAPH2) bioplex_WMM boldt hein (NCAPG2) Malo fraction boldt_WMM |
| NCAPG | NCAPH | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH) Malo gupta_WMM fraction |
| NCAPD2 | NCAPH | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH) Malo fraction boldt_WMM |
| NCAPH2 | NCAPD3 | 1.0 | 0.949 | hein_WMM bioplex (NCAPH2) bioplex_WMM hein (NCAPD3) Malo fraction |
| SMC4 | NCAPH2 | 0.999 | 0.949 | hein_WMM bioplex (NCAPH2) bioplex_WMM boldt hein (SMC4) fraction boldt_WMM |
| NCAPH | SMC2 | 0.998 | 0.936 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH) gupta_WMM fraction boldt_WMM |
| NCAPG2 | SMC4 | 0.989 | 0.902 | hein_WMM bioplex_WMM boldt youn_WMM hein (NCAPG2,SMC4) fraction boldt_WMM |
| NCAPD2 | NCAPG | 0.988 | 0.901 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| SMC4 | NCAPH | 0.988 | 0.901 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH,SMC4) gupta_WMM fraction boldt_WMM |
| NCAPD2 | SMC4 | 0.988 | 0.901 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC4) fraction boldt_WMM treiber_WMM |
| SMC4 | NCAPG | 0.988 | 0.901 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC4) gupta_WMM fraction boldt_WMM treiber_WMM |
| SMC2 | NCAPD3 | 0.968 | 0.88 | hein_WMM bioplex_WMM youn_WMM hein (NCAPD3) fraction |
| NCAPH2 | SMC2 | 0.93 | 0.846 | hein_WMM bioplex (NCAPH2) bioplex_WMM boldt fraction boldt_WMM |
| NCAPG2 | SMC2 | 0.82 | 0.773 | hein_WMM bioplex_WMM boldt youn_WMM hein (NCAPG2) fraction boldt_WMM |
| SMC4 | NCAPD3 | 0.774 | 0.752 | hein_WMM bioplex_WMM youn_WMM hein (NCAPD3,SMC4) fraction treiber_WMM |
| NCAPD2 | SMC2 | 0.252 | 0.476 | hein_WMM bioplex_WMM boldt youn_WMM fraction boldt_WMM treiber_WMM |
| NCAPG | SMC2 | 0.114 | 0.384 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| NCAPH2 | EXPH5 | 0.028 | 0.231 | bioplex (NCAPH2) bioplex_WMM |
| SMC4 | EXPH5 | 0.008 | 0.057 | bioplex_WMM youn_WMM WMM_only |
| NCAPD3 | EXPH5 | 0.008 | 0.029 | bioplex_WMM WMM_only |
| SMC2 | EXPH5 | 0.007 | 0.007 | bioplex_WMM youn_WMM WMM_only |
| NCAPG2 | EXPH5 | 0.007 | 0.011 | bioplex_WMM WMM_only |
| NCAPD2 | NCAPH2 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| NCAPH | EXPH5 | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| NCAPG | EXPH5 | 0.007 | 0.004 | bioplex_WMM youn_WMM WMM_only |
| NCAPG2 | NCAPG | 0.007 | 0.001 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| NCAPD2 | NCAPD3 | 0.007 | 0.006 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| NCAPG | NCAPD3 | 0.006 | 0.004 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| NCAPG2 | NCAPD2 | 0.006 | 0.003 | hein_WMM bioplex_WMM WMM_only |
| NCAPH | NCAPD3 | 0.006 | 0.012 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| NCAPG2 | NCAPH | 0.006 | 0.003 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| NCAPG | NCAPH2 | 0.005 | 0.011 | hein_WMM bioplex (NCAPH2) bioplex_WMM |
| NCAPH | NCAPH2 | 0.005 | 0.009 | hein_WMM bioplex (NCAPH2) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_01363 has an average edge precision of 0.474 which is ranked 2669 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NCAPH | HuMAP2_01363 HuMAP2_02781 |
| NCAPD2 | HuMAP2_01363 HuMAP2_02781 |
| SMC2 | HuMAP2_01363 HuMAP2_02781 HuMAP2_05812 |
| SMC4 | HuMAP2_01363 HuMAP2_02781 HuMAP2_05812 |
| NCAPG | HuMAP2_01363 HuMAP2_02781 |
| NCAPD3 | HuMAP2_01363 HuMAP2_02768 HuMAP2_02781 |
| EXPH5 | HuMAP2_01363 HuMAP2_03172 |
| NCAPG2 | HuMAP2_01363 HuMAP2_02768 HuMAP2_02781 |
| NCAPH2 | HuMAP2_01363 HuMAP2_02781 HuMAP2_03172 |