hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01369
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDIA6 | Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) | UniProt NCBI |
| CDCP1 | CUB domain-containing protein 1 (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (Transmembrane and associated with src kinases) (CD antigen CD318) | UniProt NCBI |
| MINPP1 | Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) | UniProt NCBI |
| VWA1 | von Willebrand factor A domain-containing protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8957275 | 0.0390714342086 | 0.5 | VWA1 PDIA6 | Post-translational protein phosphorylation |
| REAC:R-HSA-1855231 | 0.0499190562503 | 0.25 | MINPP1 | Synthesis of IPs in the ER lumen |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VWA1 | CDCP1 | 0.121 | 0.393 | bioplex (CDCP1) bioplex_WMM |
| VWA1 | PDIA6 | 0.059 | 0.328 | bioplex (PDIA6) bioplex_WMM |
| VWA1 | MINPP1 | 0.022 | 0.208 | bioplex (MINPP1) |
| CDCP1 | PDIA6 | 0.007 | 0.002 | bioplex (CDCP1) |
| PDIA6 | MINPP1 | 0.006 | 0.004 | bioplex (MINPP1) bioplex_WMM gupta_WMM |
Images
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Complex HuMAP2_01369 has an average edge precision of 0.187 which is ranked 6344 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDIA6 | HuMAP2_01369 HuMAP2_01492 HuMAP2_03134 |
| CDCP1 | HuMAP2_01369 HuMAP2_02092 HuMAP2_06226 |
| MINPP1 | HuMAP2_01369 HuMAP2_02092 HuMAP2_06621 |
| VWA1 | HuMAP2_01369 HuMAP2_02092 HuMAP2_06226 |