hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01371
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CCDC6 | Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4) | UniProt NCBI |
| LZTS3 | Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1) | UniProt NCBI |
| PPP4R1 | Serine/threonine-protein phosphatase 4 regulatory subunit 1 | UniProt NCBI |
| CHEK1 | Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1) | UniProt NCBI |
| EHD2 | EH domain-containing protein 2 (PAST homolog 2) | UniProt NCBI |
| NAT9 | N-acetyltransferase 9 (EC 2.3.1.-) (Embryo brain-specific protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2446 | 0.0205911896387 | 0.333333333333 | CHEK1 CCDC6 | Retinoblastoma Gene in Cancer |
| CORUM:2171 | 0.0499726005494 | 0.166666666667 | CHEK1 | Ubiquitin E3 ligase (CHEK1, CUL4A) |
| CORUM:2714 | 0.0499726005494 | 0.166666666667 | CHEK1 | Ubiquitin E3 ligase (CHEK1, CUL1) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CCDC6 | PPP4R1 | 1.0 | 0.949 | hein_WMM bioplex (CCDC6) bioplex_WMM hein (CCDC6,PPP4R1) boldt_WMM |
| CCDC6 | LZTS3 | 0.174 | 0.433 | bioplex (CCDC6) bioplex_WMM youn_WMM |
| CCDC6 | CHEK1 | 0.036 | 0.264 | boldt fraction boldt_WMM |
| CHEK1 | EHD2 | 0.027 | 0.231 | fraction |
| CHEK1 | NAT9 | 0.02 | 0.184 | bioplex (NAT9) bioplex_WMM |
| PPP4R1 | LZTS3 | 0.008 | 0.081 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01371 has an average edge precision of 0.357 which is ranked 3805 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CCDC6 | HuMAP2_00469 HuMAP2_01371 HuMAP2_01644 HuMAP2_03906 HuMAP2_04313 |
| LZTS3 | HuMAP2_01371 HuMAP2_01644 HuMAP2_03906 HuMAP2_04313 |
| PPP4R1 | HuMAP2_00469 HuMAP2_01371 HuMAP2_02007 HuMAP2_04313 |
| CHEK1 | HuMAP2_01371 HuMAP2_05132 HuMAP2_05849 HuMAP2_06351 HuMAP2_06418 |
| EHD2 | HuMAP2_01371 HuMAP2_05132 HuMAP2_06418 |
| NAT9 | HuMAP2_01371 HuMAP2_05132 HuMAP2_05849 HuMAP2_06418 |