hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01380
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ELP5 | Elongator complex protein 5 (Dermal papilla-derived protein 6) (S-phase 2 protein) | UniProt NCBI |
| ELP6 | Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103) | UniProt NCBI |
| ZBTB25 | Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP) | UniProt NCBI |
| PIPOX | Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase) | UniProt NCBI |
| ELP4 | Elongator complex protein 4 (hELP4) (PAX6 neighbor gene protein) | UniProt NCBI |
| ZBTB2 | Zinc finger and BTB domain-containing protein 2 | UniProt NCBI |
| ZNF639 | Zinc finger protein 639 (Zinc finger protein ANC_2H01) (Zinc finger protein ZASC1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6332 | 6.75899855318e-08 | 0.428571428571 | ELP4 ELP6 ELP5 | Elongator complex (ELP1, ELP2, ELP3, ELP4, ELP5, ELP6) |
| GO:0033588 | 0.000111163123615 | 0.428571428571 | ELP4 ELP6 ELP5 | Elongator holoenzyme complex |
| REAC:R-HSA-3214847 | 0.00482901899519 | 0.428571428571 | ELP4 ELP6 ELP5 | HATs acetylate histones |
| REAC:R-HSA-3247509 | 0.0323160255015 | 0.428571428571 | ELP4 ELP6 ELP5 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.0323160255015 | 0.428571428571 | ELP4 ELP6 ELP5 | Chromatin organization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ELP6 | ELP4 | 1.0 | 0.949 | bioplex (ELP6) bioplex_WMM youn_WMM gupta_WMM |
| ELP6 | ELP5 | 0.998 | 0.936 | bioplex (ELP6) bioplex_WMM youn_WMM gupta_WMM |
| ZNF639 | ELP6 | 0.895 | 0.821 | bioplex (ELP6) bioplex_WMM |
| PIPOX | ELP4 | 0.884 | 0.816 | bioplex (PIPOX) bioplex_WMM |
| ELP6 | ZBTB2 | 0.607 | 0.673 | bioplex (ELP6) bioplex_WMM |
| ZNF639 | ZBTB2 | 0.6 | 0.671 | hein_WMM bioplex_WMM hein (ZBTB2) |
| PIPOX | ELP5 | 0.112 | 0.381 | bioplex (PIPOX) bioplex_WMM |
| ELP6 | ZBTB25 | 0.049 | 0.293 | bioplex (ELP6) bioplex_WMM |
| ELP6 | PIPOX | 0.025 | 0.215 | bioplex (PIPOX) bioplex_WMM |
| ELP4 | ELP5 | 0.013 | 0.151 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZBTB25 | ZBTB2 | 0.01 | 0.109 | bioplex_WMM WMM_only |
| ZBTB25 | ELP4 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| ZBTB25 | ELP5 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| ZNF639 | ELP4 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| ZNF639 | ZBTB25 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| ZNF639 | ELP5 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ELP4 | ZBTB2 | 0.008 | 0.044 | bioplex_WMM WMM_only |
| ELP5 | ZBTB2 | 0.008 | 0.026 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01380 has an average edge precision of 0.364 which is ranked 3713 out of all 6965 complexes.
Related Complexes