hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01407
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KDM4A | Lysine-specific demethylase 4A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) | UniProt NCBI |
| CCL22 | C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)] | UniProt NCBI |
| KDM4B | Lysine-specific demethylase 4B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B) | UniProt NCBI |
| ZNF414 | Zinc finger protein 414 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3214842 | 0.0117756117682 | 0.5 | KDM4B KDM4A | HDMs demethylate histones |
| REAC:R-HSA-5693565 | 0.0284687652941 | 0.5 | KDM4B KDM4A | Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| REAC:R-HSA-5693606 | 0.0292253078855 | 0.5 | KDM4B KDM4A | DNA Double Strand Break Response |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZNF414 | KDM4B | 1.0 | 0.949 | bioplex (ZNF414) bioplex_WMM |
| KDM4A | CCL22 | 0.397 | 0.558 | bioplex (CCL22) bioplex_WMM |
| KDM4A | KDM4B | 0.34 | 0.528 | bioplex (KDM4B) bioplex_WMM |
| ZNF414 | KDM4A | 0.218 | 0.465 | bioplex (ZNF414) bioplex_WMM |
Images
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Complex HuMAP2_01407 has an average edge precision of 0.625 which is ranked 1803 out of all 6965 complexes.
Related Complexes