hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01411
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I) | UniProt NCBI |
| IMPDH2 | Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) (IMPDH-II) | UniProt NCBI |
| ANKRD9 | Ankyrin repeat domain-containing protein 9 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-73817 | 0.000441698392473 | 0.666666666667 | IMPDH1 IMPDH2 | Purine ribonucleoside monophosphate biosynthesis |
| REAC:R-HSA-8956320 | 0.000702607572674 | 0.666666666667 | IMPDH1 IMPDH2 | Nucleobase biosynthesis |
| KEGG:00983 | 0.0011410864499 | 0.666666666667 | IMPDH1 IMPDH2 | Drug metabolism - other enzymes |
| GO:0003938 | 0.00135247023414 | 0.666666666667 | IMPDH1 IMPDH2 | IMP dehydrogenase activity |
| GO:0006183 | 0.00135247023414 | 0.666666666667 | IMPDH1 IMPDH2 | GTP biosynthetic process |
| KEGG:00230 | 0.00272070891872 | 0.666666666667 | IMPDH1 IMPDH2 | Purine metabolism |
| GO:1901070 | 0.00811409485621 | 0.666666666667 | IMPDH1 IMPDH2 | guanosine-containing compound biosynthetic process |
| REAC:R-HSA-15869 | 0.0243796532655 | 0.666666666667 | IMPDH1 IMPDH2 | Metabolism of nucleotides |
| GO:0042451 | 0.0283955176165 | 0.666666666667 | IMPDH1 IMPDH2 | purine nucleoside biosynthetic process |
| GO:0042455 | 0.0283955176165 | 0.666666666667 | IMPDH1 IMPDH2 | ribonucleoside biosynthetic process |
| GO:0046129 | 0.0283955176165 | 0.666666666667 | IMPDH1 IMPDH2 | purine ribonucleoside biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IMPDH1 | IMPDH2 | 0.999 | 0.949 | hein_WMM bioplex (IMPDH1,IMPDH2) bioplex_WMM Malo fraction boldt_WMM |
| ANKRD9 | IMPDH2 | 0.829 | 0.775 | bioplex (IMPDH2) bioplex_WMM |
| IMPDH1 | ANKRD9 | 0.566 | 0.653 | bioplex (IMPDH1) bioplex_WMM |
Images
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Complex HuMAP2_01411 has an average edge precision of 0.792 which is ranked 949 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IMPDH1 | HuMAP2_01411 HuMAP2_02658 |
| IMPDH2 | HuMAP2_01411 HuMAP2_03814 |
| ANKRD9 | HuMAP2_01411 HuMAP2_02658 HuMAP2_03814 |