hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01412
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HLTF | Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) | UniProt NCBI |
| PMPCA | Mitochondrial-processing peptidase subunit alpha (Alpha-MPP) (P-55) | UniProt NCBI |
| ODAPH | Odontogenesis associated phosphoprotein | UniProt NCBI |
| PMPCB | Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (P-52) | UniProt NCBI |
| NUDT8 | Nucleoside diphosphate-linked moiety X motif 8 (Nudix motif 8) (EC 3.6.1.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8949664 | 0.00161668141155 | 0.4 | PMPCA PMPCB | Processing of SMDT1 |
| REAC:R-HSA-8949215 | 0.00340529843133 | 0.4 | PMPCA PMPCB | Mitochondrial calcium ion transport |
| GO:0017087 | 0.0135228859698 | 0.4 | PMPCA PMPCB | mitochondrial processing peptidase complex |
| REAC:R-HSA-1268020 | 0.0237053784759 | 0.4 | PMPCA PMPCB | Mitochondrial protein import |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PMPCA | PMPCB | 1.0 | 0.949 | bioplex (PMPCA) bioplex_WMM Guru youn_WMM fraction |
| PMPCA | NUDT8 | 0.144 | 0.407 | bioplex (PMPCA) bioplex_WMM |
| NUDT8 | ODAPH | 0.098 | 0.358 | bioplex (ODAPH) |
| PMPCA | HLTF | 0.081 | 0.35 | bioplex (PMPCA) bioplex_WMM |
| ODAPH | PMPCB | 0.06 | 0.336 | bioplex (ODAPH) |
| PMPCA | ODAPH | 0.03 | 0.231 | bioplex (ODAPH) |
| NUDT8 | PMPCB | 0.011 | 0.145 | bioplex_WMM WMM_only |
| NUDT8 | HLTF | 0.007 | 0.002 | bioplex_WMM WMM_only |
| HLTF | PMPCB | 0.006 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01412 has an average edge precision of 0.309 which is ranked 4468 out of all 6965 complexes.
Related Complexes