hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01414
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IL17RB | Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor) | UniProt NCBI |
| RGS19 | Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) | UniProt NCBI |
| RGS20 | Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1) | UniProt NCBI |
| TTC7B | Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1) | UniProt NCBI |
| FAM126A | Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A) | UniProt NCBI |
| SELENOO | Protein adenylyltransferase SelO, mitochondrial (EC 2.7.7.-) (EC 2.7.7.n1) (Selenoprotein O) (SelO) | UniProt NCBI |
| NARF | Nuclear prelamin A recognition factor (Iron-only hydrogenase-like protein 2) (IOP2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6890 | 6.04024714829e-05 | 0.285714285714 | TTC7B FAM126A | Phosphatidylinositol 4-kinase complex |
| REAC:R-HSA-418597 | 0.0296729390946 | 0.285714285714 | RGS19 RGS20 | G alpha (z) signalling events |
| CORUM:6209 | 0.0499886427319 | 0.142857142857 | RGS20 | MT1-G(i)-RGS20 complex |
| CORUM:6211 | 0.0499886427319 | 0.142857142857 | RGS20 | RSG20-MT1-MT2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TTC7B | RGS20 | 0.187 | 0.439 | bioplex (RGS20) bioplex_WMM |
| RGS20 | NARF | 0.108 | 0.373 | bioplex (RGS20) bioplex_WMM |
| RGS20 | SELENOO | 0.079 | 0.351 | bioplex (RGS20) bioplex_WMM |
| RGS20 | FAM126A | 0.07 | 0.348 | bioplex (RGS20) bioplex_WMM |
| RGS19 | RGS20 | 0.069 | 0.348 | bioplex (RGS20) bioplex_WMM |
| SELENOO | IL17RB | 0.036 | 0.264 | bioplex (IL17RB) bioplex_WMM |
| RGS19 | TTC7B | 0.008 | 0.091 | bioplex_WMM WMM_only |
| TTC7B | NARF | 0.008 | 0.087 | bioplex_WMM WMM_only |
| RGS19 | NARF | 0.008 | 0.067 | bioplex_WMM WMM_only |
| TTC7B | FAM126A | 0.008 | 0.067 | bioplex_WMM WMM_only |
| RGS19 | FAM126A | 0.008 | 0.04 | bioplex_WMM WMM_only |
| TTC7B | SELENOO | 0.008 | 0.033 | bioplex_WMM WMM_only |
| FAM126A | NARF | 0.008 | 0.025 | bioplex_WMM WMM_only |
| RGS19 | SELENOO | 0.008 | 0.01 | bioplex_WMM WMM_only |
| SELENOO | NARF | 0.007 | 0.003 | bioplex_WMM WMM_only |
| FAM126A | SELENOO | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01414 has an average edge precision of 0.159 which is ranked 6633 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IL17RB | HuMAP2_01414 HuMAP2_03547 |
| RGS19 | HuMAP2_01414 |
| RGS20 | HuMAP2_01414 |
| TTC7B | HuMAP2_01414 |
| FAM126A | HuMAP2_01414 HuMAP2_04279 HuMAP2_04770 HuMAP2_06460 |
| SELENOO | HuMAP2_01414 HuMAP2_03547 |
| NARF | HuMAP2_01414 |