hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01418
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HSPA1B | Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) | UniProt NCBI |
| PDXP | Pyridoxal phosphate phosphatase (PLP phosphatase) (EC 3.1.3.3) (EC 3.1.3.74) (Chronophin) | UniProt NCBI |
| METTL21A | Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A) | UniProt NCBI |
| ISYNA1 | Inositol-3-phosphate synthase 1 (IPS 1) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (MI-1-P synthase) (MIP synthase) (hIPS) (Myo-inositol 1-phosphate synthase A1) (hINO1) | UniProt NCBI |
| ALDOA | Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) | UniProt NCBI |
| ALDOC | Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) | UniProt NCBI |
| NIT1 | Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.128) (Nitrilase homolog 1) | UniProt NCBI |
| GSTO2 | Glutathione S-transferase omega-2 (GSTO-2) (EC 2.5.1.18) (Glutathione S-transferase omega 2-2) (GSTO 2-2) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00030 | 0.00489222565408 | 0.25 | ALDOC ALDOA | Pentose phosphate pathway |
| KEGG:00051 | 0.00635546714027 | 0.25 | ALDOC ALDOA | Fructose and mannose metabolism |
| KEGG:01100 | 0.0101915709661 | 0.625 | PDXP ALDOC GSTO2 ALDOA ISYNA1 | Metabolic pathways |
| WP:WP534 | 0.0119507998541 | 0.25 | ALDOC ALDOA | Glycolysis and Gluconeogenesis |
| REAC:R-HSA-70263 | 0.0193257881708 | 0.25 | ALDOC ALDOA | Gluconeogenesis |
| KEGG:00010 | 0.0233191717198 | 0.25 | ALDOC ALDOA | Glycolysis / Gluconeogenesis |
| KEGG:01230 | 0.029607581241 | 0.25 | ALDOC ALDOA | Biosynthesis of amino acids |
| GO:0004332 | 0.0378589948753 | 0.25 | ALDOC ALDOA | fructose-bisphosphate aldolase activity |
| WP:WP4018 | 0.0395356363713 | 0.25 | ALDOC ALDOA | Pathways in clear cell renal cell carcinoma |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ALDOA | ALDOC | 0.937 | 0.85 | hein_WMM bioplex (ALDOA,ALDOC) bioplex_WMM hein (ALDOA) fraction treiber_WMM |
| GSTO2 | ALDOA | 0.539 | 0.642 | bioplex (GSTO2) Guru fraction |
| GSTO2 | ALDOC | 0.29 | 0.492 | bioplex (GSTO2) Guru fraction |
| NIT1 | ALDOC | 0.227 | 0.468 | fraction |
| PDXP | ALDOA | 0.084 | 0.349 | bioplex_WMM fraction |
| PDXP | ALDOC | 0.068 | 0.35 | fraction |
| ISYNA1 | ALDOC | 0.066 | 0.348 | bioplex_WMM Guru fraction |
| HSPA1B | ALDOC | 0.064 | 0.348 | bioplex (ALDOC) fraction |
| NIT1 | ALDOA | 0.063 | 0.347 | bioplex (NIT1) fraction treiber_WMM |
| HSPA1B | ALDOA | 0.059 | 0.331 | bioplex (ALDOA) bioplex_WMM boldt fraction boldt_WMM |
| ISYNA1 | ALDOA | 0.05 | 0.296 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| METTL21A | HSPA1B | 0.046 | 0.292 | bioplex (METTL21A) bioplex_WMM boldt |
| ISYNA1 | PDXP | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| HSPA1B | GSTO2 | 0.007 | 0.006 | bioplex (GSTO2) |
| METTL21A | ALDOA | 0.006 | 0.007 | bioplex (METTL21A) boldt boldt_WMM |
| NIT1 | HSPA1B | 0.006 | 0.006 | bioplex (NIT1) |
| NIT1 | ISYNA1 | 0.005 | 0.013 | bioplex (NIT1) |
| HSPA1B | ISYNA1 | 0.004 | 0.01 | bioplex_WMM WMM_only |
| NIT1 | PDXP | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_01418 has an average edge precision of 0.271 which is ranked 4999 out of all 6965 complexes.
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