hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01421
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RIT1 | GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) | UniProt NCBI |
| CALD1 | Caldesmon (CDM) | UniProt NCBI |
| EID2 | EP300-interacting inhibitor of differentiation 2 (EID-2) (CREBBP/EP300 inhibitor 2) (EID-1-like inhibitor of differentiation 2) | UniProt NCBI |
| NCOA5 | Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA) | UniProt NCBI |
| KERA | Keratocan (KTN) (Keratan sulfate proteoglycan keratocan) | UniProt NCBI |
| LZTR1 | Leucine-zipper-like transcriptional regulator 1 (LZTR-1) | UniProt NCBI |
| NUDT12 | Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12) | UniProt NCBI |
| ZNF517 | Zinc finger protein 517 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0011381 | 0.0150657984869 | 0.25 | RIT1 LZTR1 | Aplasia of the semicircular canal |
| HP:0011380 | 0.0253031982095 | 0.25 | RIT1 LZTR1 | Morphological abnormality of the semicircular canal |
| HP:0002212 | 0.0347018940535 | 0.25 | RIT1 LZTR1 | Curly hair |
| HP:0011376 | 0.0347018940535 | 0.25 | RIT1 LZTR1 | Morphological abnormality of the vestibule of the inner ear |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NUDT12 | LZTR1 | 0.977 | 0.893 | bioplex (NUDT12) bioplex_WMM |
| NUDT12 | KERA | 0.469 | 0.605 | bioplex (KERA) bioplex_WMM |
| NUDT12 | NCOA5 | 0.31 | 0.502 | bioplex (NUDT12) bioplex_WMM |
| RIT1 | LZTR1 | 0.048 | 0.296 | bioplex (RIT1) bioplex_WMM |
| EID2 | KERA | 0.032 | 0.245 | bioplex (KERA) bioplex_WMM |
| CALD1 | NCOA5 | 0.028 | 0.231 | gupta_WMM fraction |
| NUDT12 | ZNF517 | 0.02 | 0.184 | bioplex (ZNF517) bioplex_WMM |
| NUDT12 | EID2 | 0.008 | 0.034 | bioplex_WMM WMM_only |
| NCOA5 | LZTR1 | 0.008 | 0.033 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01421 has an average edge precision of 0.336 which is ranked 4167 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RIT1 | HuMAP2_01421 HuMAP2_05989 |
| CALD1 | HuMAP2_01421 HuMAP2_02457 HuMAP2_06145 HuMAP2_06759 HuMAP2_06919 |
| EID2 | HuMAP2_01421 HuMAP2_03826 HuMAP2_04790 HuMAP2_05587 HuMAP2_05970 HuMAP2_06275 |
| NCOA5 | HuMAP2_01421 HuMAP2_05563 HuMAP2_06145 |
| KERA | HuMAP2_01421 HuMAP2_04790 HuMAP2_05563 HuMAP2_05587 HuMAP2_05601 HuMAP2_05970 |
| LZTR1 | HuMAP2_01421 HuMAP2_01650 HuMAP2_05563 HuMAP2_05989 |
| NUDT12 | HuMAP2_00098 HuMAP2_01421 HuMAP2_01650 HuMAP2_05563 |
| ZNF517 | HuMAP2_01421 |