hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01433
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EXOC4 | Exocyst complex component 4 (Exocyst complex component Sec8) | UniProt NCBI |
| EXOC6 | Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1) | UniProt NCBI |
| EXOC7 | Exocyst complex component 7 (Exocyst complex component Exo70) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:89 | 1.26199510107e-08 | 1.0 | EXOC4 EXOC7 EXOC6 | Exocyst Sec6/8 complex |
| CORUM:6167 | 1.26199510107e-08 | 1.0 | EXOC4 EXOC7 EXOC6 | Exocyst complex |
| REAC:R-HSA-5620916 | 4.35659406764e-07 | 1.0 | EXOC4 EXOC7 EXOC6 | VxPx cargo-targeting to cilium |
| REAC:R-HSA-264876 | 9.09984147875e-07 | 1.0 | EXOC4 EXOC7 EXOC6 | Insulin processing |
| REAC:R-HSA-5620920 | 7.29021391195e-06 | 1.0 | EXOC4 EXOC7 EXOC6 | Cargo trafficking to the periciliary membrane |
| CORUM:6169 | 1.00675659188e-05 | 0.666666666667 | EXOC7 EXOC6 | Exocyst EXOC5-EXOC6-EXOC7 subcomplex |
| REAC:R-HSA-1445148 | 2.2531998792e-05 | 1.0 | EXOC4 EXOC7 EXOC6 | Translocation of SLC2A4 (GLUT4) to the plasma membrane |
| REAC:R-HSA-2980736 | 2.35561805552e-05 | 1.0 | EXOC4 EXOC7 EXOC6 | Peptide hormone metabolism |
| WP:WP4352 | 0.000100842112761 | 1.0 | EXOC4 EXOC7 EXOC6 | Ciliary landscape |
| REAC:R-HSA-5617833 | 0.000513949964862 | 1.0 | EXOC4 EXOC7 EXOC6 | Cilium Assembly |
| REAC:R-HSA-1852241 | 0.00160990717739 | 1.0 | EXOC4 EXOC7 EXOC6 | Organelle biogenesis and maintenance |
| REAC:R-HSA-199991 | 0.0146202486223 | 1.0 | EXOC4 EXOC7 EXOC6 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.0171761243356 | 1.0 | EXOC4 EXOC7 EXOC6 | Vesicle-mediated transport |
| CORUM:6168 | 0.0499776345577 | 0.333333333333 | EXOC6 | Exocyst EXOC5-EXOC6 subcomplex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EXOC7 | EXOC6 | 1.0 | 0.949 | bioplex (EXOC6) bioplex_WMM boldt (EXOC6,EXOC7) Malo fraction boldt_WMM |
| EXOC4 | EXOC7 | 0.959 | 0.865 | bioplex_WMM boldt (EXOC4,EXOC7) fraction boldt_WMM |
| EXOC4 | EXOC6 | 0.939 | 0.851 | bioplex (EXOC6) bioplex_WMM boldt (EXOC4,EXOC6) youn_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_01433 has an average edge precision of 0.888 which is ranked 623 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EXOC4 | HuMAP2_00862 HuMAP2_01433 HuMAP2_01602 HuMAP2_03022 HuMAP2_03186 HuMAP2_06749 |
| EXOC6 | HuMAP2_00862 HuMAP2_01433 HuMAP2_01602 HuMAP2_03022 HuMAP2_03488 |
| EXOC7 | HuMAP2_00862 HuMAP2_01433 HuMAP2_01602 HuMAP2_03022 HuMAP2_03488 |