hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01455
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPIF | Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Mitochondrial cyclophilin) (CyP-M) (Rotamase F) | UniProt NCBI |
| PGM5 | Phosphoglucomutase-like protein 5 (Aciculin) (Phosphoglucomutase-related protein) (PGM-RP) | UniProt NCBI |
| LDHAL6A | L-lactate dehydrogenase A-like 6A (EC 1.1.1.27) | UniProt NCBI |
| ALDH7A1 | Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase) | UniProt NCBI |
| ESD | S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D) (Methylumbelliferyl-acetate deacetylase) (EC 3.1.1.56) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00620 | 0.00316574451287 | 0.4 | LDHAL6A ALDH7A1 | Pyruvate metabolism |
| KEGG:00010 | 0.00831682765542 | 0.4 | LDHAL6A ALDH7A1 | Glycolysis / Gluconeogenesis |
| WP:WP4228 | 0.0497141369515 | 0.2 | ALDH7A1 | Vitamin B6-dependent and responsive disorders |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPIF | ESD | 0.964 | 0.872 | bioplex_WMM fraction |
| PPIF | PGM5 | 0.86 | 0.796 | fraction |
| PPIF | LDHAL6A | 0.783 | 0.756 | fraction |
| ALDH7A1 | PPIF | 0.739 | 0.738 | bioplex_WMM Guru fraction |
| ESD | LDHAL6A | 0.007 | 0.012 | fraction |
| ALDH7A1 | PGM5 | 0.0 | 0.009 | fraction |
| ALDH7A1 | LDHAL6A | 0.0 | 0.006 | fraction |
| PGM5 | LDHAL6A | 0.0 | 0.0 | fraction |
| ALDH7A1 | ESD | 0.0 | 0.001 | bioplex_WMM fraction |
Images
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Complex HuMAP2_01455 has an average edge precision of 0.354 which is ranked 3863 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPIF | HuMAP2_01455 |
| PGM5 | HuMAP2_01455 HuMAP2_06325 HuMAP2_06977 |
| LDHAL6A | HuMAP2_01455 HuMAP2_03979 HuMAP2_05300 |
| ALDH7A1 | HuMAP2_00890 HuMAP2_01455 HuMAP2_03443 |
| ESD | HuMAP2_01455 HuMAP2_01504 HuMAP2_05913 |