hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01459
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LSM14B | Protein LSM14 homolog B (Protein FAM61B) (RNA-associated protein 55B) (hRAP55B) | UniProt NCBI |
| SEMG1 | Semenogelin-1 (Cancer/testis antigen 103) (Semenogelin I) (SGI) [Cleaved into: Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein] | UniProt NCBI |
| NUPR1 | Nuclear protein 1 (Candidate of metastasis 1) (Protein p8) | UniProt NCBI |
| SIRT3 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) | UniProt NCBI |
| SEMG2 | Semenogelin-2 (Semenogelin II) (SGII) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1900005 | 0.00450823411379 | 0.4 | SEMG2 SEMG1 | positive regulation of serine-type endopeptidase activity |
| GO:1902573 | 0.00450823411379 | 0.4 | SEMG2 SEMG1 | positive regulation of serine-type peptidase activity |
| GO:1900003 | 0.0270421395626 | 0.4 | SEMG2 SEMG1 | regulation of serine-type endopeptidase activity |
| GO:1902571 | 0.0450641792523 | 0.4 | SEMG2 SEMG1 | regulation of serine-type peptidase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LSM14B | SEMG2 | 0.94 | 0.853 | bioplex (LSM14B) bioplex_WMM |
| LSM14B | SEMG1 | 0.177 | 0.436 | bioplex (LSM14B) bioplex_WMM youn_WMM |
| LSM14B | SIRT3 | 0.115 | 0.385 | bioplex (LSM14B) bioplex_WMM |
| NUPR1 | SEMG2 | 0.084 | 0.349 | bioplex (NUPR1) bioplex_WMM |
| SEMG1 | NUPR1 | 0.064 | 0.349 | bioplex (NUPR1) bioplex_WMM |
| SEMG1 | SEMG2 | 0.036 | 0.265 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| SEMG2 | SIRT3 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| SEMG1 | SIRT3 | 0.007 | 0.003 | bioplex_WMM WMM_only boldt_WMM |
Images
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Complex HuMAP2_01459 has an average edge precision of 0.331 which is ranked 4221 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LSM14B | HuMAP2_01459 HuMAP2_02055 HuMAP2_03909 HuMAP2_04355 HuMAP2_05474 |
| SEMG1 | HuMAP2_01459 HuMAP2_05474 HuMAP2_05891 |
| NUPR1 | HuMAP2_01459 HuMAP2_05474 HuMAP2_05891 |
| SIRT3 | HuMAP2_01459 HuMAP2_02055 HuMAP2_04355 |
| SEMG2 | HuMAP2_01459 HuMAP2_03909 HuMAP2_05474 HuMAP2_05891 |