hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01464
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DRAM2 | DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77) | UniProt NCBI |
| ADGRE2 | Adhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312) | UniProt NCBI |
| CD97 | CD97 antigen (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: CD97 antigen subunit alpha; CD97 antigen subunit beta] | UniProt NCBI |
| TPST1 | Protein-tyrosine sulfotransferase 1 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 1) (TPST-1) | UniProt NCBI |
| NNT | NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP334 | 0.000183446885704 | 0.4 | ADGRE2 CD97 | GPCRs, Class B Secretin-like |
| REAC:R-HSA-373080 | 0.0253191001807 | 0.4 | ADGRE2 CD97 | Class B/2 (Secretin family receptors) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CD97 | ADGRE2 | 1.0 | 0.949 | bioplex (CD97) bioplex_WMM |
| CD97 | NNT | 0.39 | 0.552 | bioplex (CD97) bioplex_WMM gupta_WMM |
| CD97 | DRAM2 | 0.053 | 0.301 | bioplex (CD97) bioplex_WMM |
| CD97 | TPST1 | 0.044 | 0.281 | bioplex (CD97) bioplex_WMM |
| DRAM2 | ADGRE2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| DRAM2 | TPST1 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| TPST1 | ADGRE2 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| NNT | ADGRE2 | 0.008 | 0.022 | bioplex_WMM WMM_only |
| NNT | DRAM2 | 0.008 | 0.022 | bioplex_WMM WMM_only |
| NNT | TPST1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01464 has an average edge precision of 0.239 which is ranked 5535 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DRAM2 | HuMAP2_00718 HuMAP2_01464 |
| ADGRE2 | HuMAP2_00718 HuMAP2_01464 HuMAP2_02450 |
| CD97 | HuMAP2_00718 HuMAP2_01464 HuMAP2_02450 |
| TPST1 | HuMAP2_00718 HuMAP2_00908 HuMAP2_01137 HuMAP2_01464 |
| NNT | HuMAP2_00718 HuMAP2_01464 |