hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01467
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CLEC4M | C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299) | UniProt NCBI |
| HTR1B | 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B) | UniProt NCBI |
| CD209 | CD209 antigen (C-type lectin domain family 4 member L) (Dendritic cell-specific ICAM-3-grabbing non-integrin 1) (DC-SIGN) (DC-SIGN1) (CD antigen CD209) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04625 | 0.0017077231529 | 0.666666666667 | CLEC4M CD209 | C-type lectin receptor signaling pathway |
| KEGG:05162 | 0.00361949387372 | 0.666666666667 | CLEC4M CD209 | Measles |
| KEGG:04145 | 0.00402657539006 | 0.666666666667 | CLEC4M CD209 | Phagosome |
| GO:0046968 | 0.00405722906526 | 0.666666666667 | CLEC4M CD209 | peptide antigen transport |
| KEGG:05152 | 0.00497142990217 | 0.666666666667 | CLEC4M CD209 | Tuberculosis |
| WP:WP4217 | 0.00658696465544 | 0.666666666667 | CLEC4M CD209 | Ebola Virus Pathway on Host |
| CORUM:5415 | 0.0249904952816 | 0.333333333333 | HTR1B | HTR1B homodimer complex |
| CORUM:5417 | 0.0249904952816 | 0.333333333333 | HTR1B | HTR1D-HTR1B complex |
| GO:0046790 | 0.0486736709081 | 0.666666666667 | CLEC4M CD209 | virion binding |
| GO:0019062 | 0.0486736709081 | 0.666666666667 | CLEC4M CD209 | virion attachment to host cell |
| CORUM:5416 | 0.0499776345577 | 0.333333333333 | HTR1B | HTR1A-HTR1B complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CLEC4M | CD209 | 1.0 | 0.949 | bioplex (CD209,CLEC4M) bioplex_WMM |
| HTR1B | CD209 | 0.97 | 0.881 | bioplex (CD209) bioplex_WMM |
| CLEC4M | HTR1B | 0.009 | 0.108 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01467 has an average edge precision of 0.646 which is ranked 1665 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CLEC4M | HuMAP2_01467 HuMAP2_04676 |
| HTR1B | HuMAP2_01467 HuMAP2_04676 |
| CD209 | HuMAP2_01467 HuMAP2_04420 HuMAP2_04676 |