hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01478
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DST | Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) | UniProt NCBI |
| CLASP2 | CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2) | UniProt NCBI |
| MAPRE2 | Microtubule-associated protein RP/EB family member 2 (APC-binding protein EB2) (End-binding protein 2) (EB2) | UniProt NCBI |
| MAPRE1 | Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1) | UniProt NCBI |
| KIF18B | Kinesin-like protein KIF18B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0051010 | 1.66401304789e-07 | 0.8 | MAPRE2 DST MAPRE1 CLASP2 | microtubule plus-end binding |
| GO:0035371 | 4.7240495605e-07 | 0.8 | KIF18B DST MAPRE1 MAPRE2 | microtubule plus-end |
| GO:1990752 | 2.49427518271e-06 | 0.8 | KIF18B DST MAPRE1 MAPRE2 | microtubule end |
| GO:0008017 | 2.07718623633e-05 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | microtubule binding |
| GO:0005881 | 3.84719751497e-05 | 0.8 | KIF18B CLASP2 MAPRE1 MAPRE2 | cytoplasmic microtubule |
| GO:0005874 | 4.39342287116e-05 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | microtubule |
| GO:0015631 | 9.09038692953e-05 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | tubulin binding |
| GO:0031109 | 0.000403202499238 | 0.8 | KIF18B CLASP2 MAPRE1 MAPRE2 | microtubule polymerization or depolymerization |
| GO:0099513 | 0.000555273323991 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | polymeric cytoskeletal fiber |
| GO:0000226 | 0.00136074102749 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | microtubule cytoskeleton organization |
| GO:0099512 | 0.00257059467769 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | supramolecular fiber |
| GO:0099081 | 0.0027226606524 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | supramolecular polymer |
| GO:0099080 | 0.00274868991294 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | supramolecular complex |
| GO:0051233 | 0.00407078924856 | 0.6 | KIF18B MAPRE2 MAPRE1 | spindle midzone |
| GO:0007017 | 0.00645835997489 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | microtubule-based process |
| GO:0008092 | 0.0125790618987 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | cytoskeletal protein binding |
| GO:0005819 | 0.0129837343661 | 0.8 | KIF18B CLASP2 MAPRE1 MAPRE2 | spindle |
| GO:0005876 | 0.0199719657189 | 0.6 | KIF18B CLASP2 MAPRE1 | spindle microtubule |
| GO:1904825 | 0.0270421395626 | 0.4 | MAPRE2 MAPRE1 | protein localization to microtubule plus-end |
| GO:1905725 | 0.0270421395626 | 0.4 | MAPRE2 MAPRE1 | protein localization to microtubule end |
| GO:0031110 | 0.0412952841175 | 0.6 | CLASP2 MAPRE1 MAPRE2 | regulation of microtubule polymerization or depolymerization |
| MIRNA:hsa-miR-4764-5p | 0.0435496282017 | 0.4 | KIF18B MAPRE2 | hsa-miR-4764-5p |
| GO:0015630 | 0.0477475152415 | 1.0 | MAPRE2 KIF18B DST MAPRE1 CLASP2 | microtubule cytoskeleton |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DST | MAPRE1 | 1.0 | 0.949 | hein_WMM bioplex (MAPRE1) bioplex_WMM youn_WMM hein (MAPRE1) gupta_WMM boldt_WMM |
| CLASP2 | MAPRE1 | 0.994 | 0.923 | hein_WMM bioplex (MAPRE1) bioplex_WMM boldt (MAPRE1) youn_WMM hein (MAPRE1) gupta_WMM boldt_WMM |
| MAPRE2 | MAPRE1 | 0.955 | 0.862 | bioplex (MAPRE1) bioplex_WMM boldt (MAPRE2) youn_WMM gupta_WMM fraction boldt_WMM |
| MAPRE1 | KIF18B | 0.826 | 0.774 | hein_WMM bioplex (MAPRE1) bioplex_WMM boldt (MAPRE1) youn_WMM hein (MAPRE1) boldt_WMM |
| MAPRE2 | DST | 0.008 | 0.088 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| DST | CLASP2 | 0.008 | 0.027 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| MAPRE2 | CLASP2 | 0.008 | 0.028 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DST | KIF18B | 0.008 | 0.016 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| MAPRE2 | KIF18B | 0.008 | 0.012 | bioplex_WMM youn_WMM WMM_only |
| CLASP2 | KIF18B | 0.007 | 0.009 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
Images
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Complex HuMAP2_01478 has an average edge precision of 0.369 which is ranked 3654 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DST | HuMAP2_01478 HuMAP2_01703 HuMAP2_02770 HuMAP2_03129 |
| CLASP2 | HuMAP2_01478 HuMAP2_02854 |
| MAPRE2 | HuMAP2_00486 HuMAP2_01478 HuMAP2_03288 HuMAP2_05017 |
| MAPRE1 | HuMAP2_01478 HuMAP2_01703 HuMAP2_03129 |
| KIF18B | HuMAP2_01478 HuMAP2_01703 HuMAP2_02602 HuMAP2_04670 |