hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01484
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ACKR3 | Atypical chemokine receptor 3 (C-X-C chemokine receptor type 7) (CXC-R7) (CXCR-7) (Chemokine orphan receptor 1) (G-protein coupled receptor 159) (G-protein coupled receptor RDC1 homolog) (RDC-1) | UniProt NCBI |
| GJB2 | Gap junction beta-2 protein (Connexin-26) (Cx26) | UniProt NCBI |
| TFRC | Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001581 | 0.0218987389569 | 0.666666666667 | GJB2 TFRC | Recurrent skin infections |
| HP:0000509 | 0.0264552280074 | 0.666666666667 | GJB2 TFRC | Conjunctivitis |
| HP:0025337 | 0.0271411575623 | 0.666666666667 | GJB2 TFRC | Red eye |
| CORUM:1104 | 0.0499776345577 | 0.333333333333 | TFRC | SNX complex (SNX1, SNX1a, TFRC) |
| CORUM:7359 | 0.0499776345577 | 0.333333333333 | TFRC | TF-TFRC complex |
| CORUM:7416 | 0.0499776345577 | 0.333333333333 | GJB2 | GJB2-PTK2-NANOG complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACKR3 | GJB2 | 0.024 | 0.211 | hein_WMM hein (GJB2) |
| TFRC | GJB2 | 0.021 | 0.187 | hein_WMM hein (GJB2) |
| TFRC | ACKR3 | 0.007 | 0.004 | hein_WMM WMM_only |
Images
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Complex HuMAP2_01484 has an average edge precision of 0.134 which is ranked 6810 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ACKR3 | HuMAP2_01484 HuMAP2_02163 |
| GJB2 | HuMAP2_01484 HuMAP2_02163 |
| TFRC | HuMAP2_00382 HuMAP2_01484 HuMAP2_05879 |