hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01486
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDZK1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (CFTR-associated protein of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3) | UniProt NCBI |
| SLC22A5 | Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2) | UniProt NCBI |
| SH2D5 | SH2 domain-containing protein 5 | UniProt NCBI |
| SLC6A6 | Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) | UniProt NCBI |
| SLC19A3 | Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-425366 | 0.0221443716613 | 0.4 | SLC22A5 SLC6A6 | Transport of bile salts and organic acids, metal ions and amine compounds |
| MIRNA:hsa-miR-9-5p | 0.0237018945296 | 0.6 | PDZK1 SLC19A3 SLC22A5 | hsa-miR-9-5p |
| GO:0015838 | 0.0270421395626 | 0.4 | PDZK1 SLC22A5 | amino-acid betaine transport |
| GO:0015879 | 0.0270421395626 | 0.4 | PDZK1 SLC22A5 | carnitine transport |
| CORUM:7042 | 0.0499494897235 | 0.2 | PDZK1 | PDZK1-PLCB3- SSTR2 complex |
| CORUM:7043 | 0.0499494897235 | 0.2 | PDZK1 | PDZK1-PLCB3- SSTR3 complex |
| CORUM:7044 | 0.0499494897235 | 0.2 | PDZK1 | PDZK1-PLCB3- SSTR4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDZK1 | SH2D5 | 0.877 | 0.811 | bioplex (PDZK1) bioplex_WMM |
| PDZK1 | SLC19A3 | 0.298 | 0.498 | bioplex (PDZK1) bioplex_WMM |
| PDZK1 | SLC6A6 | 0.163 | 0.42 | bioplex (PDZK1) bioplex_WMM |
| PDZK1 | SLC22A5 | 0.082 | 0.351 | bioplex (PDZK1) bioplex_WMM |
| SH2D5 | SLC19A3 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| SH2D5 | SLC22A5 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| SH2D5 | SLC6A6 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| SLC19A3 | SLC22A5 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| SLC6A6 | SLC19A3 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| SLC6A6 | SLC22A5 | 0.008 | 0.044 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_01486 has an average edge precision of 0.249 which is ranked 5397 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDZK1 | HuMAP2_01486 HuMAP2_03516 HuMAP2_05538 HuMAP2_06269 |
| SLC22A5 | HuMAP2_01486 HuMAP2_05430 HuMAP2_06269 |
| SH2D5 | HuMAP2_01486 HuMAP2_03516 HuMAP2_05538 HuMAP2_06269 |
| SLC6A6 | HuMAP2_01486 HuMAP2_05193 HuMAP2_06269 |
| SLC19A3 | HuMAP2_01486 HuMAP2_06269 |