hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01531
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RSL24D1 | Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1) (Ribosomal protein L24-like) | UniProt NCBI |
| HIST1H1T | Histone H1t (Testicular H1 histone) | UniProt NCBI |
| MRTO4 | mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4) | UniProt NCBI |
| BOP1 | Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein) | UniProt NCBI |
| PES1 | Pescadillo homolog | UniProt NCBI |
| WDR12 | Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6856 | 2.25356268047e-09 | 0.5 | PES1 BOP1 WDR12 | PeBoW complex |
| CORUM:6306 | 9.01288868683e-09 | 0.5 | PES1 BOP1 WDR12 | DDX27-PeBoW complex |
| GO:0042273 | 3.4435733921e-07 | 0.833333333333 | WDR12 RSL24D1 MRTO4 BOP1 PES1 | ribosomal large subunit biogenesis |
| GO:0030687 | 3.23372816466e-06 | 0.666666666667 | PES1 MRTO4 BOP1 WDR12 | preribosome, large subunit precursor |
| GO:0070545 | 1.81582264982e-05 | 0.5 | PES1 BOP1 WDR12 | PeBoW complex |
| GO:0042254 | 0.000277631504382 | 0.833333333333 | WDR12 RSL24D1 MRTO4 BOP1 PES1 | ribosome biogenesis |
| GO:0030684 | 0.000395345440439 | 0.666666666667 | PES1 MRTO4 BOP1 WDR12 | preribosome |
| GO:0000463 | 0.000518697707158 | 0.5 | PES1 BOP1 WDR12 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0000470 | 0.00206534926206 | 0.5 | PES1 BOP1 WDR12 | maturation of LSU-rRNA |
| GO:0022613 | 0.00270779091032 | 0.833333333333 | WDR12 RSL24D1 MRTO4 BOP1 PES1 | ribonucleoprotein complex biogenesis |
| REAC:R-HSA-6791226 | 0.00563418329838 | 0.5 | PES1 BOP1 WDR12 | Major pathway of rRNA processing in the nucleolus and cytosol |
| GO:0030686 | 0.00661098268806 | 0.5 | PES1 BOP1 WDR12 | 90S preribosome |
| REAC:R-HSA-8868773 | 0.00661628360681 | 0.5 | PES1 BOP1 WDR12 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00770517770968 | 0.5 | PES1 BOP1 WDR12 | rRNA processing |
| GO:0006364 | 0.0129505725968 | 0.666666666667 | PES1 MRTO4 BOP1 WDR12 | rRNA processing |
| GO:0016072 | 0.015875268856 | 0.666666666667 | PES1 MRTO4 BOP1 WDR12 | rRNA metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PES1 | BOP1 | 0.905 | 0.828 | bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| PES1 | WDR12 | 0.849 | 0.79 | bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| MRTO4 | PES1 | 0.451 | 0.595 | hein_WMM bioplex (MRTO4,PES1) bioplex_WMM youn_WMM gupta_WMM fraction |
| HIST1H1T | PES1 | 0.128 | 0.398 | bioplex (HIST1H1T) bioplex_WMM fraction |
| MRTO4 | RSL24D1 | 0.073 | 0.357 | bioplex (MRTO4) bioplex_WMM treiber_WMM |
| MRTO4 | WDR12 | 0.054 | 0.3 | bioplex (MRTO4) bioplex_WMM youn_WMM fraction treiber_WMM |
| WDR12 | BOP1 | 0.019 | 0.186 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| WDR12 | RSL24D1 | 0.011 | 0.145 | bioplex_WMM WMM_only |
| MRTO4 | BOP1 | 0.008 | 0.082 | bioplex (MRTO4) bioplex_WMM youn_WMM gupta_WMM |
| PES1 | RSL24D1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| BOP1 | RSL24D1 | 0.006 | 0.004 | bioplex_WMM WMM_only |
| MRTO4 | HIST1H1T | 0.006 | 0.004 | bioplex (HIST1H1T) bioplex_WMM treiber_WMM |
| HIST1H1T | WDR12 | 0.004 | 0.014 | bioplex (HIST1H1T) bioplex_WMM |
| HIST1H1T | BOP1 | 0.004 | 0.005 | bioplex (HIST1H1T) bioplex_WMM |
| HIST1H1T | RSL24D1 | 0.003 | 0.012 | bioplex (HIST1H1T) bioplex_WMM |
Images
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Complex HuMAP2_01531 has an average edge precision of 0.252 which is ranked 5349 out of all 6965 complexes.
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