hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01539
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDK13 | Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller) | UniProt NCBI |
| CDK12 | Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6796648 | 0.00316917126735 | 1.0 | CDK13 CDK12 | TP53 Regulates Transcription of DNA Repair Genes |
| GO:0070816 | 0.0247952876258 | 1.0 | CDK13 CDK12 | phosphorylation of RNA polymerase II C-terminal domain |
| GO:0019908 | 0.029754345151 | 1.0 | CDK13 CDK12 | nuclear cyclin-dependent protein kinase holoenzyme complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CDK12 | CDK13 | 0.997 | 0.934 | bioplex (CDK13) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_01539 has an average edge precision of 0.934 which is ranked 420 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CDK13 | HuMAP2_01243 HuMAP2_01539 HuMAP2_02631 HuMAP2_03159 HuMAP2_03315 HuMAP2_05800 |
| CDK12 | HuMAP2_00587 HuMAP2_01243 HuMAP2_01539 HuMAP2_02631 HuMAP2_03315 HuMAP2_03637 HuMAP2_05800 |